CN105852806A - Electronic skin for wound real-time monitoring - Google Patents
Electronic skin for wound real-time monitoring Download PDFInfo
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- CN105852806A CN105852806A CN201610172862.1A CN201610172862A CN105852806A CN 105852806 A CN105852806 A CN 105852806A CN 201610172862 A CN201610172862 A CN 201610172862A CN 105852806 A CN105852806 A CN 105852806A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
- A61B5/0531—Measuring skin impedance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
- A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
- A61B5/445—Evaluating skin irritation or skin trauma, e.g. rash, eczema, wound, bed sore
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0001—Body part
- A61F2007/0052—Body part for treatment of skin or hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
Abstract
The invention discloses electronic skin for wound real-time monitoring. On a bio-compatible flexible material (polydimethylsiloxane, flexible polyimide, collagen-chitosan/silicone rubber), various sensors, in different types, are distributed on the electronic skin for acquiring abundant physicochemical information of a wound, and the real-time transmission of data to a software service system is achieved by virtue of a Bluetooth low power consumption technology. According to the electronic skin disclosed by the invention, the physicochemical information of the wound is acquired in real time by virtue of the software system and the information is analyzed in real time, so that a current state of the wound is acquired; instructions are issued to the electronic skin as require, and by virtue of a wound temperature regulator, the wound is conditioned in accordance with a preset scheme, so that wound healing is promoted. According to the electronic skin disclosed by the invention, through cooperative work of software and hardware systems, the wound is monitored in real time and is conditioned as required.
Description
Technical field
The invention belongs to software-hardware synergism field of medical technology, be specifically related to a kind of monitor in real time for wound
Electronic skin.
Background technology
In recent years, the development of soft electronic industry is swift and violent, produces at flexible screen, flexible battery, flexible sensor etc.
Industry is played a greater and greater role.But soft electronics is the most inadequate in medical field infiltration.Medical field is due to it
Particularity, the bio-compatibility for flexible material, material has tightened up demand.On the other hand, tool
Body is to wound monitoring aspect, and traditional wound monitoring method mainly relies on unaided eye discrimination wound situation, more multiple
More miscellaneous, it is to extract wound surface body fluid to carry out further Physico-chemical tests.The former needs to rely on medical experience,
Poor accuracy, easily by subjective impact, the latter's then flow process is complicated, somewhat expensive, it is also possible to bring pain to patient
Bitter.Owing to poor accuracy or the flow process of such scheme are complicated, cause wound being carried out real-time prison
Survey, it is impossible on optimal opportunity wound carried out optimal process, therefore wound monitored system in real time
The demand of system is objective reality and urgent.
Traditional wound monitoring method takes away bandage the most exactly to observe wound, according to the physics and chemistry of wound tissue
Form judges its healing situation.On the one hand, if wound does not also heal, so it is likely to make wound be subject to
To infecting, leave the most delible scar, increase patient suffering；On the other hand, observe by the naked eye and draw
Conclusion need rely on medical experience, poor accuracy, easily by subjective impact, and qualitative conclusions can only be drawn.
More complicated monitoring method is then to extract wound surface body fluid to carry out further Physico-chemical tests.Such as,
One of Melissa L Fernande etc. finds in detection wound exudate for the research of Venous Ulcers in the recent period
Uric acid content contribute to differentiate wound the order of severity.Uric acid can deposit sodium urate crystals in wound
(Monosodium urate crystal) causes inflammatory reaction, thus suppresses wound healing.By detection wound
The composition of sepage, researcher finds when uric acid level is higher, and wound is more serious, and healing time is the most relatively
Long.Researcher is thought and can be differentiated by the uric acid in monitoring wound exudate or multiple uric acid precursor level
With the order of severity of predicted wound, there is certain diagnostic value.The rising of uric acid level is often tight with wound
Principal characteristic is proportionate, and the rising of uric acid precursor such as purine level shows that the wound order of severity is relatively low.Therefore supervise
Survey the change of the purine metabolism in wound exudate and it will be seen that the healing of chronic wounds such as Venous Ulcers etc.
Journey.It addition, Harvard Medical School professor Kang Na L Ai Wensi have developed a kind of bandage.This bandage adds
Fluorescent material, it can absorb light, be discharged simultaneously again.When wound lacks oxygen, this stretches tight
Fluorescent material in band will redden, if oxygen is sufficient, then can show green light.Thus can be by glimmering
Light color judges the oxygen supply situation of wound.But the side of the above monitoring wound surface body fluid physicochemical property
Method flow process is complicated, somewhat expensive, and wound can not be carried out real-time monitoring, it is impossible to when optimal
Machine carries out optimal process to wound.
As can be seen here, prior art is primarily present following defect:
(1) poor accuracy, a large amount of subjectivities relying on people and experience.
(2) according to Physico-chemical tests method, somewhat expensive, flow process is complicated, poor in timeliness.
(3) cannot monitor in real time, thus adjust wound physicochemical environment in real time, miss optimal conditioning opportunity.
Summary of the invention
For the above-mentioned technical problem existing for prior art, the invention provides one and supervise in real time for wound
The electronic skin surveyed, it is possible to realize monitoring on-demand conditioning in real time to wound.
A kind of electronic skin monitored in real time for wound, including hardware system and software systems；
Described hardware system includes main control unit, sensing unit and performance element；Sensing unit and perform list
Unit is fitted in wound site by PDMS (dimethyl silicone polymer), and it is (poly-that main control unit is then made in flexible PI
Acid imide) it is connected with sensing unit and performance element in substrate and by extending wire；Wherein:
Described sensing unit be used for gathering wound about temperature, humidity, swelling tension, Skin Resistance,
ECG (electrocardiogram) and the sensing data of blood oxygen change；
Described performance element for carrying out electro photoluminescence to accelerate angiogenic growth to wound, or passes through heating and melting
The medicine of fat parcel carries out anti-inflammatory to wound, or stimulates antibacterials to carry out wound by ultraviolet excitation
Release, or wound is cooled down；
Described main control unit is for collecting the sensing data of sensing unit offer and by bluetooth by sensing data
Send software systems to, receive the control instruction that software systems send simultaneously, and then control performance element to wound
Choma border is adjusted, and promotes wound healing；
Described software systems load on intelligent terminal, it include bluetooth communication module, data calibration module,
Data visualization module, data analysis module and warning module；Wherein:
Described bluetooth communication module for collecting the sensing obtained by Bluetooth protocol wireless receiving main control unit
Data；
Described data calibration module is calibrated for the sensing data receiving bluetooth communication module；
Described data visualization module takes various forms and the sensing data after calibration carries out visualization behaviour
Make；
Described data analysis module based on calibration after sensing data, it is judged that wound be in the initial stage, mid-term or
In the concrete stage of healing stage, analyze wound climate the most normal；When abnormal conditions occurs in wound climate, logical
Cross bluetooth communication module and send the control instruction adjusting wound climate to main control unit；
Described warning module is analyzed, when judging to deposit near wound surface based on the sensing data after calibration
In the case of weight or boiling the hottest object, send alarm to the wounded.
Further, described main control unit includes central processing unit, memory, I2C interface and bluetooth sky
Line etc..
Further, described flexible PI substrate is combined with skin regeneration material, and skin regeneration material directly connects
Touch wound surface, there is good biocompatibility, skin corium can be induced to regenerate.
Described skin regeneration material uses by collagen-chitin dermis scaffold and has certain thickness silicon rubber
Film is formed by the adhesive bonds that biocompatibility is good.
Further, described sensing unit includes interdigital electrode, tension meter, temperature sensor, humidity
Sensor, photodiode etc..Described performance element include heater, cooler, ultraviolet leds and
Electric radiant Heating Film etc..Wherein, interdigital electrode realizes Skin Resistance and ECG measures, it is judged that skin growth situation, with
Time may be used for apply electro photoluminescence stimulate angiogenic growth；Heater can heat wound, it is also possible to inflammation position
Put hot melt fat inclusion enclave release antiphlogistic (different temperatures)；Blood oxygen uses photodiode to receive and measures.
Further, the visualized operation of described data visualization module includes showing each sensor of sensing unit
Monitoring Data, show the curve map of each sensor historic data, show the semantic information of each sensing data.
Further, described data analysis module collects the wound all biographies in each stage of different patient
Sensor historical data, is formed and organizes training sample more；Then use training sample that SVM classifier is trained,
Form wound disaggregated model；And then utilize this model that the stage residing for wound is classified, form diagnosis knot
Really.
Further, described warning module uses vibrating alert, sound prompting, pictograph prompting etc. many
The mode of kind sends alarm to the wounded.
Described software systems have analysis, operational capability, are responsible for the acquisition of data, analyze and control refers to
The generation of order；Described hardware system is responsible for the collection of data and the execution to control instruction, and both are jointly
Wound monitoring service.
Described intelligent terminal can be smart mobile phone, panel computer or PC etc..
The hardware components of electronic skin of the present invention utilizes the physics and chemistry letter that various kinds of sensors Real-time Collection wound is abundant
Breath, utilizes Bluetooth Low Energy technology to realize the data real-time transmission to software systems, utilizes polydimethylsiloxanes
Alkane material realizes bio-compatibility, utilizes wound thermoregulator to nurse one's health wound by presupposed solution；Soft
Part part obtains wound physics and chemistry information in real time, and analyzes information in real time, obtains the shape that wound is current
State, sends instruction as required, is adjusted the environment of wound, promotes wound healing；Software and hardware system
Collaborative work, monitors in real time to wound and on-demand conditioning.
Accompanying drawing explanation
Fig. 1 is the structural representation of electronic skin of the present invention.
Fig. 2 is the collaborative work flow process schematic diagram of electronic skin software and hardware system of the present invention.
Detailed description of the invention
In order to more specifically describe the present invention, below in conjunction with the accompanying drawings and the detailed description of the invention skill to the present invention
Art scheme is described in detail.
The electronic skin that the present invention monitors in real time for wound includes hardware system and software systems two parts, two
The mutually coordinated control of person, target is the change of monitoring wound, nurses one's health wound by presupposed solution, promotes
Wound healing；As shown in Figure 1:
Hardware system based on TI company CC2541 Sensor Tag 1.4 platform, including main control chip, sensor,
The parts such as actuator, pro-skin encapsulating material, skin regeneration material.
Pro-skin encapsulating material is the flexible material of MULTILAYER COMPOSITE, including PDMS, flexible PI substrate；Skin is again
Green material uses by collagen-chitin dermis scaffold and has certain thickness silicone rubber membrane and pass through biocompatibility
Good adhesive bonds forms.Flexible PI substrate is combined with collagen-chitin/silicon rubber skin regeneration material,
Regrown material directly contacts the surface of a wound, has good biocompatibility, and skin corium can be induced to regenerate.
Main control chip is TI company CC2541, it include central processing unit, memory, I2C interface and
Bluetooth 4.0 module；Main control chip is made in (diameter 1 cm) in pro-skin encapsulating material flexibility PI substrate,
There is flexible foldable properties, and be embedded in gauze, by the extending wire of PDMS and sensor/execution
Device connects, and sensor/actuator is made on ductile PDMS, can be fitted in wound site completely also
Keep at the volley being in close contact with wound site, and there is the bio-compatibilities such as water-permeable and air permeable.
In electronic skin be distributed multiple sensors, the temperature of wound site, humidity, pressure (swelling tension),
Skin Resistance, ECG electrocardio and blood oxygen 6 sensing amounts of change；Be distributed simultaneously ultraviolet leds, Electric radiant Heating Film,
The actuators such as fat packaging medicine.The device of transducing part uses multiplexing integrated technology: interdigital electrode realizes skin
Impedance and ECG measure, it is judged that skin growth situation, may be used for applying electro photoluminescence simultaneously and stimulate angiogenic growth,
Heater can heat wound, it is also possible to inflammatory sites hot melt fat inclusion enclave is discharged antiphlogistic (not equality of temperature
Degree).Blood oxygen uses the infrarede emitting diode of TI platform and photodiode to receive and measure.Major calculations is examined
It is to give mobile phone and cloud platform operation thereof that disconnected and doctor obtains data in real time, and main control MCU uses TI company
Sensor TAG platform, is merely that sensing data collects scheduling, wireless receiving and dispatching coding and output actuator work
The effect made.Sensor side uses flexible electronic technology to realize extending flexible folding design, can be real
Flexibly connecting of existing elongation 200%.
Software system deployment, on outside smart mobile phone, is led to hardware system by Bluetooth Low Energy agreement
Letter, on the one hand receives the sensing data monitored, and on the other hand according to the scheme preset, sends out hardware system
Go out to adjust the instruction of wound climate, and according to the data such as pressure, temperature, simulated skin sense of touch, carry out early warning.
Software systems be divided into bluetooth communication module, data calibration module, data visualization module, data analysis module,
Warning module；Wherein:
Bluetooth communication module, it utilizes Bluetooth Low Energy agreement to dock with hardware system and the multiple biography of real-time reception
The data of sensor.This module can need collection frequency and the data acquisition of single of setting data according to user
Amount, equilibrium establishment between power consumption and collection packing density, and use database purchase historical data.
Data calibration module, the initial data collected is calibrated by it, improves the data precision.Typically
For, Systematic Errors can be there is because of its individual difference, initial data in sensor.Therefore hardware system is disposed
Before wound, first the sensor such as temperature, pressure is done data pre-sampling, use special instrument to obtain simultaneously
Obtain the correction data of a group of temperature, pressure etc..Then use least square method by sensing data and contrast number
According to doing linear fit, obtain one group of fitting coefficient, using this coefficient as calibration parameter, wound prison later
During survey, the initial data of sensor is carried out calibration process, can reduce and be made by sensor individuals difference
The Systematic Errors become.
Data visualization module, data are visualized by it by various ways, facilitate patient to check wound reality
Time state.Three levels of visualization point:
(1) Monitoring Data of each sensor is shown.To the sensing data after calibration, directly display it real-time
Numerical value.
(2) curve map of historical data is shown.To the sensing data in nearest a period of time, show in real time
It changes curve；Owing to historical data has stored in intelligent mobile phone terminal, therefore can also show that deployment is hard
Data movement curve in any a period of time after part system, in order to the evolution of wound status is examined
Disconnected.
(3) semantic information of data is shown.The implication of the concrete numerical value of each sensor is not often known due to patient,
It is thus desirable to according to medical practice, transfer the numerical value such as temperature, pressure to semantic information.Here five it are classified as
Shelves: too high, high, normal, low, too low, the threshold value of each grade sets according to medical practice.For each
Shelves, show different patterns and word on intelligent mobile phone terminal, so can tell patient its wound in real time
Whether situation is in normal range (NR).
Data analysis module, the wound data received are analyzed by real time, according to existing medical science warp
Test, it is judged that wound is in the different phases such as initial stage, mid-term, healing stage；Analyze wound climate the most normal,
And feed back to hardware system to adjust wound climate.First the wound biography in each stage of different patient is collected
Sensor historical data, forms training sample；Then use training sample that SVM classifier is trained, shape
Become wound disaggregated model；SVM classifier is applied to newly deployed hardware system, to the stage residing for wound
Classify, form diagnostic result.In each stage, according to environment such as the temperature of wound, humidity, pressure
Data judge that it is the most normal.When abnormal conditions occurs in wound climate, send feedback command to hardware system,
Heat it or refrigeration etc. processes, wherein, and the wound that blood oxygen partially slow for healing is on the low side, is stung by electricity
Swash and accelerate angiogenic growth；The medicine wrapped up by heating and melting fat for light inflammation carries out anti-inflammatory；For
Infective wound surface, by ultraviolet excitation, stimulates antibacterials release.
Warning module, after it is analyzed (setting threshold value) to the perception numerical values recited such as pressure, temperature and scope,
May determine that near wound surface, whether there is the contact of weight, sharp thing, cross and scald object etc., if above-mentioned danger occurs
Situation (exceedes threshold value), and software systems can send alarm to the wounded；Alert methods have vibrating alert, sound prompting,
The various ways such as pictograph prompting.
Present embodiment electronic skin software-hardware synergism flow process, as shown in Figure 2:
1. pair hardware system is energized, and is deployed on wound.
2. hardware system wireless communication module sends wait communication signal.
3. software systems are opened, and hardware system sets up regularly wireless connection.
4. software systems obtain all kinds of sensing data in real time from hardware system.
5. the data obtained comprehensively are analyzed by software systems:
5.1 under dangerous situation software systems issue the user with early warning alarm.
5.2 in the case of needs affect wound software systems send control instruction to hardware system, as hindered
Mouth heating etc..
The above-mentioned description to embodiment is to be understood that for ease of those skilled in the art and apply
The present invention.Above-described embodiment obviously easily can be made various amendment by person skilled in the art,
And General Principle described herein is applied in other embodiments without through performing creative labour.Therefore,
The invention is not restricted to above-described embodiment, those skilled in the art, according to the announcement of the present invention, do for the present invention
The improvement and the amendment that go out all should be within protection scope of the present invention.
Claims (10)
1. the electronic skin monitored in real time for wound, including hardware system and software systems；Its feature
It is:
Described hardware system includes main control unit, sensing unit and performance element；Sensing unit and perform list
Unit is fitted in wound site by PDMS, and main control unit is then made in flexible PI substrate and by extending
Wire is connected with sensing unit and performance element；Wherein:
Described sensing unit be used for gathering wound about temperature, humidity, swelling tension, Skin Resistance,
ECG and the sensing data of blood oxygen change；
Described performance element for carrying out electro photoluminescence to accelerate angiogenic growth to wound, or passes through heating and melting
The medicine of fat parcel carries out anti-inflammatory to wound, or stimulates antibacterials to carry out wound by ultraviolet excitation
Release, or wound is cooled down；
Described main control unit is for collecting the sensing data of sensing unit offer and by bluetooth by sensing data
Send software systems to, receive the control instruction that software systems send simultaneously, and then control performance element to wound
Choma border is adjusted, and promotes wound healing；
Described software systems load on intelligent terminal, it include bluetooth communication module, data calibration module,
Data visualization module, data analysis module and warning module；Wherein:
Described bluetooth communication module for collecting the sensing obtained by Bluetooth protocol wireless receiving main control unit
Data；
Described data calibration module is calibrated for the sensing data receiving bluetooth communication module；
Described data visualization module takes various forms and the sensing data after calibration carries out visualization behaviour
Make；
Described data analysis module based on calibration after sensing data, it is judged that wound be in the initial stage, mid-term or
In the concrete stage of healing stage, analyze wound climate the most normal；When abnormal conditions occurs in wound climate, logical
Cross bluetooth communication module and send the control instruction adjusting wound climate to main control unit；
Described warning module is analyzed, when judging to deposit near wound surface based on the sensing data after calibration
In the case of weight or boiling the hottest object, send alarm to the wounded.
Electronic skin the most according to claim 1, it is characterised in that: during described main control unit includes
Central processor, memory, I2C interface and Bluetooth antenna.
Electronic skin the most according to claim 1, it is characterised in that: described flexible PI substrate and skin
Skin regrown material combines, and skin regeneration material directly contacts wound surface.
Electronic skin the most according to claim 3, it is characterised in that: described skin regeneration material is adopted
Pass through, with having certain thickness silicone rubber membrane, the glue that biocompatibility is good with by collagen-chitin dermis scaffold
Stick bonding forms.
Electronic skin the most according to claim 1, it is characterised in that: described sensing unit includes fork
Refer to electrode, tension meter, temperature sensor, humidity sensor and photodiode.
Electronic skin the most according to claim 1, it is characterised in that: described performance element includes adding
Hot device, cooler, ultraviolet leds and Electric radiant Heating Film.
Electronic skin the most according to claim 1, it is characterised in that: described data visualization module
Visualized operation includes showing the Monitoring Data of each sensor of sensing unit, showing each sensor historic data
Curve map, show the semantic information of each sensing data.
Electronic skin the most according to claim 1, it is characterised in that: described data analysis module is received
The wound of the different patient of collection, in all the sensors historical data in each stage, is formed and organizes training sample more；So
SVM classifier is trained by rear use training sample, forms wound disaggregated model；And then utilize this model
Stage residing for wound is classified, forms diagnostic result.
Electronic skin the most according to claim 1, it is characterised in that: described warning module uses and shakes
Dynamic prompting, sound prompting or pictograph are reminded and are sent alarm to the wounded.
Electronic skin the most according to claim 1, it is characterised in that: described intelligent terminal is intelligence
Mobile phone, panel computer or PC.
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| CN201610172862.1A CN105852806B (en) | 2016-03-24 | 2016-03-24 | A kind of electronic skin monitored in real time for wound |
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| CN201610172862.1A CN105852806B (en) | 2016-03-24 | 2016-03-24 | A kind of electronic skin monitored in real time for wound |
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| CN106880348A (en) * | 2017-03-17 | 2017-06-23 | 昆山维信诺科技有限公司 | Class transdermal medical device and mobile terminal |
| CN107412949A (en) * | 2017-06-22 | 2017-12-01 | 浙江大学 | Wound healing promoting electronic plaster and its application method |
| CN107684433A (en) * | 2017-07-24 | 2018-02-13 | 浙江大学 | Device and method that is a kind of while detecting a variety of physiological parameter indexs of the surface of a wound |
| CN107811616A (en) * | 2016-09-14 | 2018-03-20 | 中国科学院宁波材料技术与工程研究所 | A kind of flexible many reference amounts human body physical sign detector and its application method |
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| CN109793516A (en) * | 2019-01-21 | 2019-05-24 | 浙江大学 | A kind of skin pricktest impedance flexible detection device and skin pricktest impedance detection method |
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| CN110358297A (en) * | 2018-12-29 | 2019-10-22 | 钛深科技(深圳)有限公司 | Ionic rubber elastomer and preparation method thereof, from electronic type electronic skin |
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| CN112704488B (en) * | 2020-12-11 | 2022-06-07 | 西安交通大学 | Wound damage state monitoring devices based on flexible ventilative hydrogel membrane |
| CN112704488A (en) * | 2020-12-11 | 2021-04-27 | 西安交通大学 | Wound damage state monitoring devices based on flexible ventilative hydrogel membrane |
| CN113827401A (en) * | 2021-09-10 | 2021-12-24 | 重庆大学 | Integrated electronic gauze system |
| CN114041799A (en) * | 2021-10-29 | 2022-02-15 | 南京大学 | Stretchable patterned metal wire for electrical interconnection in flexible sensor and processing technology |
| CN114041799B (en) * | 2021-10-29 | 2023-07-25 | 南京大学 | Stretchable patterned metal wire for electrical interconnection in flexible sensor and processing technology |
| CN113842270A (en) * | 2021-11-09 | 2021-12-28 | 清华大学 | Contraction hemostatic plaster based on liquid crystal elastomer reticular lattice structure and preparation method thereof |
| CN114469519A (en) * | 2022-01-27 | 2022-05-13 | 长沙海润生物技术有限公司 | Negative-pressure coupling electric field signal feedback treatment system |
| CN115645149A (en) * | 2022-12-14 | 2023-01-31 | 宁夏医科大学总医院 | Intelligent dressing system for chronic wounds |
| CN115645149B (en) * | 2022-12-14 | 2024-01-23 | 宁夏医科大学总医院 | Intelligent dressing system for chronic wounds |
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