CN105250074A - Wound infection degree monitoring system and method - Google Patents

Wound infection degree monitoring system and method Download PDF

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Publication number
CN105250074A
CN105250074A CN201510581304.6A CN201510581304A CN105250074A CN 105250074 A CN105250074 A CN 105250074A CN 201510581304 A CN201510581304 A CN 201510581304A CN 105250074 A CN105250074 A CN 105250074A
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CN
China
Prior art keywords
wave length
wound
light
adhesive layer
layer
Prior art date
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Pending
Application number
CN201510581304.6A
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Chinese (zh)
Inventor
张贯京
陈兴明
邓立
吴君华
张舒林
克里斯基捏·普拉纽克
李荣秀
高伟明
周亮
吴伟钊
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Qian Haiyilao Science And Technology Ltd Of Shenzhen
Shenzhen Qianhai AnyCheck Information Technology Co Ltd
Shenzhen Beiwo Deke Biotechnology Research Institute Co Ltd
Original Assignee
Qian Haiyilao Science And Technology Ltd Of Shenzhen
Shenzhen Qianhai AnyCheck Information Technology Co Ltd
Shenzhen Beiwo Deke Biotechnology Research Institute Co Ltd
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Application filed by Qian Haiyilao Science And Technology Ltd Of Shenzhen, Shenzhen Qianhai AnyCheck Information Technology Co Ltd, Shenzhen Beiwo Deke Biotechnology Research Institute Co Ltd filed Critical Qian Haiyilao Science And Technology Ltd Of Shenzhen
Priority to CN201510581304.6A priority Critical patent/CN105250074A/en
Priority to PCT/CN2015/098615 priority patent/WO2017041386A1/en
Publication of CN105250074A publication Critical patent/CN105250074A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0077Devices for viewing the surface of the body, e.g. camera, magnifying lens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive plasters or dressings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F2013/00361Plasters
    • A61F2013/00902Plasters containing means
    • A61F2013/00906Plasters containing means for transcutaneous or transdermal drugs application
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F2013/00361Plasters
    • A61F2013/00902Plasters containing means
    • A61F2013/0094Plasters containing means for sensing physical parameters

Abstract

The invention discloses a wound infection degree monitoring system and method; the method comprises the following steps: generating light of a first wavelength; calculating the first wavelength light absorptivity by a PH sensitive membrane according to photoelectric current generated by irradiation of the first wavelength light on a photoelectric diode, and determining PH value of the present wound according to a preset corresponding relation between the PH value and the absorptivity; determining the infection degree of the present wound according to a preset corresponding relation between the PH value and the infection degree of the wound. The system and method can monitor the infection degree of the wound, can remind a patient to change fresh dressing according to the infection degree, thus better treating the wound.

Description

Wound infection degree monitoring system and method
Technical field
The present invention relates to wound first-aid equipment, particularly relate to a kind of wound infection degree monitoring system and method.
Background technology
Binder is in order to material that is fixing and protection wound.Common binder has polytype, and the simplest one is single canopy band, is made up of gauze or cotton, is applicable to extremity, afterbody, head and thorax abdomen.Another kind is multiple binder, can make various shape according to body part and shape, and material is double-layer cloth, the Cotton Gossypii of different-thickness can be pressed from both sides between double-layer cloth, periphery has cloth, so that knotting is fixing, as eye bandage, back of the body waist binder, shirtfront binder, abdomen binder etc.
But above-mentioned binder is only only applicable to wrap up anastalsis, cannot monitor wound, doctor or patient cannot understand the gradient of infection of wound by binder.Further, described binder cannot remind patient to change dressings in time according to the gradient of infection of wound.
Summary of the invention
Main purpose of the present invention is to provide a kind of wound infection degree monitoring system, is intended to solve common binder and cannot monitors the gradient of infection of wound and remind the defect of changing dressing for patient according to gradient of infection.
For achieving the above object, the invention provides a kind of wound infection degree monitoring system, this system comprises: monitoring equipment, binder body and the intelligence sensor be arranged on binder body, wherein, described monitoring equipment comprises photodiode, the first light source, fiber coupler and processor, described photodiode is connected with described processor, and described first light source is connected with described fiber coupler;
Described intelligence sensor comprises the first multimode fibre, the second multimode fibre and single-mode fiber, described single-mode fiber between described first multimode fibre and described second multimode fibre and formed straight line connect, described single-mode fiber surface-coated has one deck PH sensitive membrane, when described binder body is pasted on wound, described intelligence sensor is positioned on wound;
Described fiber coupler is connected with described first multimode fibre, and described second multimode fibre is connected with described photodiode;
Described first light source, for generation of the light of first wave length, and sends to described fiber coupler by the light of described first wave length;
Described fiber coupler, for giving described first multimode fibre by the optical transport of described first wave length, the light of described first wave length is through described single-mode fiber extremely described second multimode fibre;
Described photoelectric diode, for receiving the light of first wave length from the second multimode fibre, and photoelectric current when described photoelectric diode is penetrated in the illumination producing first wave length;
Described processor, the photoelectric current produced for penetrating photoelectric diode according to the illumination of first wave length calculates described PH sensitive membrane to the absorbance of the light of first wave length, and according to the corresponding relation preset between pH value and absorbance, determines the pH value of current wound; And
Described processor, also for according to the corresponding relation preset between pH value and the gradient of infection of wound, determines the gradient of infection of current wound.
Preferably, described PH sensitive membrane is mapped to the rate of change of the photoelectric current that photoelectric diode produces to the illumination that the absorbance of the light of first wave length is first wave length.
Preferably, described monitoring equipment also comprises secondary light source, this secondary light source is connected with described fiber coupler, this secondary light source is for generation of the light of second wave length, this fiber coupler is also for accumulating a branch of combined light by the light of first wave length and the light of second wave length, and being transmitted into the first multimode fibre, described combined light is through described single-mode fiber extremely described second multimode fibre.
Preferably, described photoelectric diode, also for receiving the light of second wave length in described combined light from the second multimode fibre, and the photoelectric current of the illumination producing second wave length when penetrating photoelectric diode, if when photoelectric current when photoelectric diode is penetrated in the illumination of this second wave length is not in preset range, the transmission path of the light of first wave length and the light of second wave length is corrected, until photoelectric current when photoelectric diode is penetrated in the illumination of second wave length is in preset range by described fiber coupler.
Preferably, described PH sensitive membrane comprises three kinds of pH value indicators, and these three kinds of pH value indicators are bromophenol blue, phenol red and bromocresol purple.
Preferably, described binder body comprises cover layer, medicine layer and adhesive layer, and described cover layer and medicine layer are pasted, and described medicine layer and adhesive layer are pasted, wherein:
Described medicine layer is provided with for pasting bonding strip on described adhesive layer and multiple salient point comprising lysozyme, described salient point is arranged at the surface that described medicine layer and adhesive layer are pasted, the bonding strip of described medicine layer is arranged at the edge on the surface that described medicine layer and adhesive layer are pasted, and described medicine layer is a kind of adhesive structure that can tear from adhesive layer; And
Described adhesive layer is provided with multiple mesh and the bonding strip for pasting edge of wound, the bonding strip of described adhesive layer is arranged at the edge on described adhesive layer surface, when described adhesive layer and medicine layer are pasted, described salient point is embedded in described mesh, and described salient point and Wound contact are to sterilize to wound by lysozyme.
Preferably, this system also comprises display device, and this display device is used for the gradient of infection according to wound, medicine layer described in reminding user to replace.
On the other hand, present invention also offers a kind of wound infection degree monitoring method adopting above-mentioned wound infection degree monitoring system, the method comprises the steps:
First light source generates the light of first wave length;
By fiber coupler, the light of first wave length is sent to the first multimode fibre of intelligence sensor, the light of described first wave length passes second multimode fibre of single-mode fiber to intelligence sensor;
When photodiode receives the light of described first wave length from the second multimode fibre of intelligence sensor, produce photoelectric current when described photoelectric diode is penetrated in the illumination of first wave length;
Processor is penetrated according to the illumination of first wave length the photoelectric current that photoelectric diode produces and is calculated described PH sensitive membrane to the absorbance of the light of first wave length, and according to the corresponding relation preset between pH value and absorbance, determines the pH value of current wound; And
Processor, according to the corresponding relation preset between pH value and the gradient of infection of wound, determines the gradient of infection of current wound.
Preferably, described binder body comprises cover layer, medicine layer and adhesive layer, and described cover layer and medicine layer are pasted, and described medicine layer and adhesive layer are pasted, wherein:
Described medicine layer is provided with for pasting bonding strip on described adhesive layer and multiple salient point comprising lysozyme, described salient point is arranged at the surface that described medicine layer and adhesive layer are pasted, the bonding strip of described medicine layer is arranged at the edge on the surface that described medicine layer and adhesive layer are pasted, and described medicine layer is a kind of adhesive structure that can tear from adhesive layer; And
Described adhesive layer is provided with multiple mesh and the bonding strip for pasting edge of wound, the bonding strip of described adhesive layer is arranged at the edge on described adhesive layer surface, when described adhesive layer and medicine layer are pasted, described salient point is embedded in described mesh, and described salient point and Wound contact are to sterilize to wound by lysozyme.
Preferably, the method also comprises step: according to the gradient of infection of current wound, by medicine layer described in display device reminding user to replace.
Compared to prior art, wound infection degree monitoring system of the present invention have employed technique scheme, reaches following technique effect: the gradient of infection of monitoring wound, and reminds changing dressing for patient according to gradient of infection, is conducive to processing wound in time.
Accompanying drawing explanation
Fig. 1 is the functional frame composition of wound infection degree monitoring system of the present invention preferred embodiment;
Fig. 2 is the structural representation of intelligence sensor in wound infection degree monitoring system of the present invention;
Fig. 3 is schematic diagram when intelligence sensor is pasted on wound in wound infection degree monitoring system of the present invention;
Fig. 4 is the flow chart of the preferred embodiment of wound infection degree detecting method of the present invention;
Fig. 5 is the schematic diagram of the preferred embodiment of the corresponding relation preset between absorbance of the present invention and pH value;
Fig. 6 is the cross-sectional view of binder body preferred embodiment in wound infection degree monitoring system of the present invention;
Fig. 7 is the planar structure schematic diagram of the preferred embodiment of binder body drug layer of the present invention;
Fig. 8 is the planar structure schematic diagram of the preferred embodiment of adhered layer in binder body of the present invention;
Fig. 9 is the cross-sectional view that binder body bumps of the present invention is combined with mesh.
The realization of the object of the invention, functional characteristics and advantage will in conjunction with the embodiments, are described further with reference to accompanying drawing.
Detailed description of the invention
For further setting forth the present invention for the technological means reaching above-mentioned purpose and take and effect, below in conjunction with accompanying drawing and preferred embodiment, describe in detail bright to the specific embodiment of the present invention, structure, feature and effect thereof.Should be appreciated that specific embodiment described in the invention only in order to explain the present invention, be not intended to limit the present invention.
For realizing the object of the invention, the invention provides a kind of wound infection degree monitoring system, detecting the gradient of infection of wound, thus facilitating doctor or patient to understand the situation of wound, be conducive to the healing of wound.
As shown in Figure 1, Fig. 1 is the functional frame composition of wound infection degree monitoring system of the present invention preferred embodiment.In the present embodiment, described wound infection degree monitoring system 100 comprises monitoring equipment 1, binder body 2 and intelligence sensor 20.
Described monitoring equipment 1 comprises photodiode 10, first light source 121, secondary light source 122, fiber coupler 14, processor 16 and display device 18.Wherein, described first light source 121 and secondary light source 122 are connected with described fiber coupler 14, and described photodiode 10 is connected with described processor 16, and described processor 16 is connected with described display device 18.
The light of first wave length for generation of the light of first wave length, and is sent to described fiber coupler 14 by described first light source 121.In the present embodiment, the light of described first wave length is the light of 590 nanometers.
The light of second wave length for generation of the light of second wave length, and is sent to described fiber coupler 14 by described secondary light source 122.In the present embodiment, the light of described second wave length is the light of 860 nano wave lengths.
The light of first wave length and the light of second wave length are accumulated a branch of combined light by described fiber coupler 14, and correct the propagation path of combined light.Specifically, the light (i.e. the light of a branch of first wave length and the light of a branch of second wave length) of two bundle different wave lengths is become a branch of combined light by refraction and transmission by described fiber coupler 14, that is, the propagation path of light of two bundle different wave lengths is made to reach consistent.
Described photoelectric diode 10 for receiving combined light, and the signal of telecommunication (namely the light of first wave length and the illumination of second wave length are mapped to the photoelectric current that photoelectric diode 10 produces) corresponding to the light (i.e. optical signal) of the light of first wave length in combined light and second wave length converts to.In other embodiments, described photoelectric diode 10 also can accept separately the light (or light of second wave length) of first wave length, the light (or light of second wave length) of first wave length is converted to the corresponding signal of telecommunication.
Described processor 16 is for the signal of telecommunication of the signal of telecommunication of light corresponding conversion and the light corresponding conversion of second wave length that obtain first wave length from described photodiode 10, and analyzing and processing is carried out, to monitor the gradient of infection of wound to the signal of telecommunication of the signal of telecommunication of the light corresponding conversion of described first wave length and the light corresponding conversion of second wave length.
Described display device 18 is for the signal of telecommunication of the light corresponding conversion of the signal of telecommunication and second wave length that show the light corresponding conversion of described first wave length, and further, described display device 18 is also for the gradient of infection of the pH value and wound that show wound.
Described intelligence sensor 20 is arranged on the sticking veneer of binder body 2.This sticking veneer is provided with medical viscose glue, makes binder body 2 can be pasted on the skin of human body and not come off.Described intelligence sensor 20 can be positioned at the optional position (as long as described binder body 2 can cover described intelligence sensor 20 completely) of the sticking veneer of binder body 2.Described binder body 2 may be, but not limited to, medical proof fabric.
Shown in figure 2, Fig. 2 is the structural representation of intelligence sensor in wound infection degree monitoring system of the present invention, described intelligence sensor 20 comprises the first multimode fibre 201, second multimode fibre 203 and single-mode fiber 202, described single-mode fiber 202 between the first multimode fibre 201 and the second multimode fibre 203 and formed straight line connect.Described first multimode fibre 201, second multimode fibre 203 and single-mode fiber 202 are cylindrical.Described single-mode fiber 202 surface coverage has one deck PH sensitive membrane 2020, and this PH sensitive membrane 2020 adopts colloidal sol and gel method preparation.This PH sensitive membrane 2020 comprises multiple pH value indicator, and specifically, described PH sensitive membrane 2020 comprises three kinds of pH value indicators (e.g., bromophenol blue, phenol red and bromocresol purple).By the pH value indicator in described PH sensitive membrane 2020, shown in composition graphs 3, Fig. 3 is schematic diagram when intelligence sensor is pasted on wound in wound infection degree monitoring system of the present invention, and described intelligence sensor 20 can monitor the pH value (can monitor from pH value 2.0 ~ 9.0) of wound 3.By monitoring the pH value of wound 3, the gradient of infection of wound 3 can be judged.Such as, pH value is normal between 4.0 to 4.5, and represent not infecting of wound 3, pH value is abnormal between 7.5 to 9.0, represents wound 3 inflammation.Specifically, when the pH value change of wound 3, the color of the pH value indicator in PH sensitive membrane 2020 changes, thus also changes to the absorbance of the light of first wave length.
The shape of described binder body 2 may be, but not limited to, rectangle, square, circle etc.In the present embodiment, for the ease of monitoring the gradient of infection of wound, described intelligence sensor 20 is arranged at the centre position of described binder body 2, when making binder body 2 just in time be pasted on wound, described intelligence sensor 20 is positioned at the position (region that in other words, wound is the most serious) of wound.As shown in Figure 3, when binder body 2 is pasted on wound 3, described intelligence sensor 20 is positioned on wound 3.
As shown in Figure 1, described fiber coupler 14 is connected with the first multimode fibre 201, described second multimode fibre 203 is connected with photoelectric diode 10, combined light (be namely a branch of combined light that the light of 590 nanometers and the light of 860 nano wave lengths combine by wavelength) is transmitted into the first multimode fibre 201 by described fiber coupler 14, makes combined light pass the first multimode fibre 201, single-mode fiber 202 and the second multimode fibre 203.
When described combined light is propagated in described single-mode fiber 202, the absorption that described PH sensitive membrane 2020 can be carried out in various degree to the light of first wave length, and described PH sensitive membrane 2020 affected the change of the absorbance of the light of first wave length by the pH value of wound 3.Have default corresponding relation between the absorbance of the light of described PH sensitive membrane 2020 pairs of first wave length and the pH value of wound 3, specifically, the pH value of wound 3 is larger, and the absorbance of the light of described PH sensitive membrane 2020 pairs of first wave length is higher.There is default corresponding relation between the absorbance of the light of described PH sensitive membrane 2020 pairs of first wave length and the pH value of wound 3, obtain according to great many of experiments test, and be stored in monitoring equipment 1.As shown in Figure 5, Fig. 5 is the schematic diagram of the preferred embodiment of the corresponding relation preset between absorbance of the present invention and pH value, when pH value is 2, the absorbance of the light of described PH sensitive membrane 2020 pairs of first wave length is 0, if when pH value is 4, the absorbance of the light of described PH sensitive membrane 2020 pairs of first wave length is 10%.
In the present embodiment, it should be noted that, described photoelectric diode 10 obtains the light of first wave length from described second multimode fibre 203, and converting the light of described first wave length to the signal of telecommunication, the signal of telecommunication converted to according to the light of described first wave length calculates the absorbance of the light of described PH sensitive membrane 2020 pairs of first wave length.The described signal of telecommunication refers on photodiode 10 because produced photoelectric current is penetrated in the illumination of first wave length.Wherein, the intensity of the light of first wave length is directly proportional to described photoelectric current.The light of described PH sensitive membrane 2020 pairs of first wave length carries out absorption in various degree, can weaken the intensity of the light of first wave length.
In the present embodiment, the illumination that the absorbance of the light of described PH sensitive membrane 2020 pairs of first wave length is first wave length is mapped to the rate of change of the photoelectric current that photoelectric diode 10 produces.Specifically, a=c/b, wherein, b is the light of described first wave length photoelectric current of obtaining of described photoelectric diode 10 when being absorbed, c is the light of the described first wave length photoelectric current that described photoelectric diode 10 obtains when being absorbed by PH sensitive membrane 2020, a is the rate of change of photoelectric current, namely the absorbance of the light of described PH sensitive membrane 2020 pairs of first wave length.
When described combined light is propagated in described single-mode fiber 202, due to the pH value indicator object properties in described PH sensitive membrane 2020, described PH sensitive membrane 2020 can not absorb the light of described second wave length (i.e. the light of 860 nano wave lengths), therefore, whether correctly the light path of combined light can be corrected by the light of second wave length.Specifically, described photoelectric diode 10 obtains the light of second wave length from described second multimode fibre 203, and converts the light of described second wave length to the signal of telecommunication.The described signal of telecommunication refers on photodiode 10 because produced photoelectric current is penetrated in the illumination of second wave length.If the illumination of described second wave length penetrates produced photoelectric current in preset range (such as, between 30 microamperes to 40 microamperes), then show that the propagation path of combined light is correct, if the illumination of described second wave length penetrate produced photoelectric current not in preset range (such as, between 30 microamperes to 40 microamperes), show that the propagation path of combined light is incorrect, then adjust fiber coupler 14, make the illumination of described second wave length penetrate produced photoelectric current in preset range.
Further, as shown in Figure 6, Fig. 6 is the cross-sectional view of binder body preferred embodiment in wound infection degree monitoring system of the present invention, in the present embodiment, described binder body 2 is made up of trilaminate material, is respectively cover layer 22, medicine layer 24 and adhesive layer 26.Described cover layer 22 is pasted with medicine layer 24, and described medicine layer 24 is pasted with adhesive layer 26.
Wherein, described cover layer 22 is water proof non-woven gauze layer, this water proof non-woven gauze layer can effectively prevent external environment condition from polluting binder body 2, and described water proof non-woven gauze layer specifically can adopt waterproof cotton water thorn five to spin the water proof non-woven gauze layer of layer of cloth or other any appropriate.The surface that described cover layer 22 and medicine layer 24 are pasted scribbles medical cream, and cover layer 22 and medicine layer 24 are pasted.
As shown in Figure 7, Fig. 7 is the planar structure schematic diagram of the preferred embodiment of binder body drug layer.In the present embodiment, described medicine layer 24 comprises bonding strip 241, and this bonding strip 241 is positioned at the marginal position of medicine layer 24, and described bonding strip 241 is pasted with described adhesive layer 26, and described medicine layer 24 is pasted together with adhesive layer 26.In addition, the surface (namely described medicine layer 24 comprises the surface of bonding strip 241) that described medicine layer 24 and adhesive layer 26 are pasted has evenly or the salient point 240 of uneven distribution.Described salient point 240 may be, but not limited to, the salient point of circular salient point, rhombus salient point, square salient point, rectangle salient point or other shape.Described salient point 240 is the granule comprising lysozyme (Lysozyme), and this lysozyme can sterilize to wound.Due to described salient point 240 One's name is legion, in other embodiments, part salient point 240 is made up of the composite bed of moisture High hydrophilous resin, and the composite bed of this moisture High hydrophilous resin, for absorbing the sepage of the wound of skin, is conducive to the healing of the wound of skin.That is, in the salient point that medicine layer 24 is all, part is the salient point (also can be described as the first salient point) comprising lysozyme, and part is the salient point (also can be described as the second salient point) comprising moisture High hydrophilous resin.Described medicine layer 24 can be gauze or medical plastic.It should be noted that, the described medicine layer 2 being pasted on described adhesive layer 3 surface can tear.That is, described medicine layer 2 is a kind of adhesive structures that can tear from adhesive layer 3, conveniently changes dressings, is conducive to the healing of the wound of skin, reduces the secondary injury to the wound of skin when changing dressings.
As shown in Figure 8, Fig. 8 is the planar structure schematic diagram of the preferred embodiment of adhered layer in binder body.In the present embodiment, the surface that described adhesive layer 26 and medicine layer 24 are pasted comprises multiple being evenly distributed or uneven mesh 260, and described mesh 260 may be, but not limited to, the mesh 260 of circle, rhombus, square, rectangle or other shape.Described adhesive layer 26 another side comprises bonding strip 260, and this bonding strip 260 is positioned at the edge of adhesive layer 26, and this bonding strip 260 is for pasting the edge of the wound of skin.This binder body 2 also includes intelligence sensor 20, and this intelligence sensor 20 is positioned at adhesive layer 26.
As shown in Figure 9, Fig. 9 is the cross-sectional view that binder body bumps is combined with mesh.Composition graphs 7 and Fig. 8, when described adhesive layer 26 is pasted with medicine layer 24, described salient point 240 to be embedded in described mesh 260 (as shown in Figure 9, salient point 240 is embedded into mesh 260), make described salient point 240 and the Wound contact of skin, the wound of skin is sterilized and/or absorbs wound exudate.Described adhesive layer 26 is gauze or medical plastic, this medical plastic frivolous (between 0.01 to 0.1 millimeter) and soft.
Present invention also offers a kind of wound infection degree monitoring method adopting above-mentioned wound infection degree monitoring system.As shown in Figure 4, Fig. 4 is the flow chart of the preferred embodiment of wound infection degree detecting method of the present invention.Composition graphs 1, in the present embodiment, described wound infection degree detecting method comprises the following steps:
Step S10: generate the light of first wave length and the light of second wave length.Particularly, generated the light of first wave length by the first light source 121, secondary light source 122 generates the light of second wave length.Specifically, the light of described first wave length is the light of 590 nanometers, and the light of described second wave length is the light of 860 nanometers.
Step S11: the light of first wave length and the light of second wave length are accumulated a branch of combined light by fiber coupler 14, and send to the first multimode fibre 201 with intelligence sensor 20.
Step S12: judge that whether the illumination of second wave length penetrates photoelectric current that photodiode produces in preset range.Particularly, photodiode 10 receives the light of first wave length combined light from the second multimode fibre 203 of intelligence sensor 20, and judge that whether the illumination of second wave length penetrates photoelectric current that photodiode 10 produces preset range (such as, between 30 microamperes to 40 microamperes).When the illumination of second wave length penetrates photoelectric current that photodiode 10 produces not in preset range, flow process enters step S13.When the illumination of second wave length penetrates photoelectric current that photodiode 10 produces in preset range, flow process enters step S14.
Step S13: the propagation path being adjusted combined light by described fiber coupler 14, until the illumination of second wave length penetrates photoelectric current that photodiode produces in preset range.
Step S14: described photodiode 10 receives the light of first wave length combined light from the second multimode fibre 203, when the light of calculating first wave length passes the single-mode fiber 202 of intelligence sensor 20, the PH sensitive membrane on single-mode fiber 202 surface is to the absorbance of the light of first wave length.Specifically, the illumination that the absorbance of the light of described PH sensitive membrane 2020 pairs of first wave length is first wave length is mapped to the rate of change of the photoelectric current that photoelectric diode 10 produces.Specifically, a=c/b, wherein, b is the light of described first wave length photoelectric current of obtaining of described photoelectric diode 10 when being absorbed, c is the light of the described first wave length photoelectric current that described photoelectric diode 10 obtains when being absorbed by described PH sensitive membrane 2020, a is the rate of change of photoelectric current, namely the absorbance of the light of described PH sensitive membrane 2020 pairs of first wave length.
Step S15: processor 16, according to the corresponding relation preset between the absorbance of the light of described PH sensitive membrane 2020 pairs of first wave length and the pH value of wound, determines the pH value of current wound 3.Specifically, as shown in Figure 5, if when described absorbance is 10%, the pH value of described wound 3 is 4.
Step S16: described processor 16, according to the corresponding relation preset between pH value and the gradient of infection of wound, determines the gradient of infection of current wound 3, and pass through the gradient of infection of the current wound of the current display of display device 18.Specifically, if determined pH value is 4.0 to 4.5, represents that wound 3 does not infect, display device 18 shows character " normally ", if determined pH value is between 7.5 to 9.0, represent wound 3 inflammation, upper display character " inflammation ".In other embodiments, when described processor 16 is inflammation according to the gradient of infection of wound 3, reminding user is changed dressings, i.e. medicine layer 24 described in reminding user to replace.
It should be noted that, in above-mentioned flow chart, secondary light source 122 can not generate the light of second wave length, thus, just the light of first wave length is sent to the first multimode fibre 201 with intelligence sensor 20, and step S12 and S13 can omit in step S11.
These are only preferred embodiment of the present invention; not thereby the scope of the claims of the present invention is limited; every utilize description of the present invention and accompanying drawing content to do equivalent structure or equivalent function conversion; or be directly or indirectly used in other relevant technical fields, be all in like manner included in scope of patent protection of the present invention.

Claims (10)

1. a wound infection degree monitoring system, it is characterized in that, this system comprises: monitoring equipment, binder body and the intelligence sensor be arranged on binder body, wherein, described monitoring equipment comprises photodiode, the first light source, fiber coupler and processor, described photodiode is connected with described processor, and described first light source is connected with described fiber coupler;
Described intelligence sensor comprises the first multimode fibre, the second multimode fibre and single-mode fiber, described single-mode fiber between described first multimode fibre and described second multimode fibre and formed straight line connect, described single-mode fiber surface-coated has one deck PH sensitive membrane, when described binder body is pasted on wound, described intelligence sensor is positioned on wound;
Described fiber coupler is connected with described first multimode fibre, and described second multimode fibre is connected with described photodiode;
Described first light source, for generation of the light of first wave length, and sends to described fiber coupler by the light of described first wave length;
Described fiber coupler, for giving described first multimode fibre by the optical transport of described first wave length, the light of described first wave length is through described single-mode fiber extremely described second multimode fibre;
Described photoelectric diode, for receiving the light of first wave length from the second multimode fibre, and photoelectric current when described photoelectric diode is penetrated in the illumination producing first wave length;
Described processor, the photoelectric current produced for penetrating photoelectric diode according to the illumination of first wave length calculates described PH sensitive membrane to the absorbance of the light of first wave length, and according to the corresponding relation preset between pH value and absorbance, determines the pH value of current wound; And
Described processor, also for according to the corresponding relation preset between pH value and the gradient of infection of wound, determines the gradient of infection of current wound.
2. wound infection degree monitoring system as claimed in claim 1, it is characterized in that, described PH sensitive membrane is mapped to the rate of change of the photoelectric current that photoelectric diode produces to the illumination that the absorbance of the light of first wave length is first wave length.
3. wound infection degree monitoring system as claimed in claim 1, it is characterized in that, described monitoring equipment also comprises secondary light source, this secondary light source is connected with described fiber coupler, this secondary light source is for generation of the light of second wave length, this fiber coupler also for the light of first wave length and the light of second wave length are accumulated a branch of combined light, and is transmitted into the first multimode fibre, and described combined light is through described single-mode fiber extremely described second multimode fibre.
4. wound infection degree monitoring system as claimed in claim 3, it is characterized in that, described photoelectric diode, also for receiving the light of second wave length in described combined light from the second multimode fibre, and the photoelectric current of the illumination producing second wave length when penetrating photoelectric diode, if when photoelectric current when photoelectric diode is penetrated in the illumination of this second wave length is not in preset range, the transmission path of the light of first wave length and the light of second wave length is corrected, until photoelectric current when photoelectric diode is penetrated in the illumination of second wave length is in preset range by described fiber coupler.
5. wound infection degree monitoring system as claimed in claim 1, it is characterized in that, described PH sensitive membrane comprises three kinds of pH value indicators, and these three kinds of pH value indicators are bromophenol blue, phenol red and bromocresol purple.
6. the wound infection degree monitoring system according to any one of claim 1 to 5, is characterized in that, described binder body comprises cover layer, medicine layer and adhesive layer, and described cover layer and medicine layer are pasted, and described medicine layer and adhesive layer are pasted, wherein:
Described medicine layer is provided with for pasting bonding strip on described adhesive layer and multiple salient point comprising lysozyme, described salient point is arranged at the surface that described medicine layer and adhesive layer are pasted, the bonding strip of described medicine layer is arranged at the edge on the surface that described medicine layer and adhesive layer are pasted, and described medicine layer is a kind of adhesive structure that can tear from adhesive layer; And
Described adhesive layer is provided with multiple mesh and the bonding strip for pasting edge of wound, the bonding strip of described adhesive layer is arranged at the edge on described adhesive layer surface, when described adhesive layer and medicine layer are pasted, described salient point is embedded in described mesh, and described salient point and Wound contact are to sterilize to wound by lysozyme.
7. wound infection degree monitoring system as claimed in claim 6, it is characterized in that, this system also comprises display device, and this display device is used for the gradient of infection according to wound, medicine layer described in reminding user to replace.
8. adopt a wound infection degree monitoring method for the wound infection degree monitoring system according to any one of claim 1 to 7, it is characterized in that, the method comprises the steps:
First light source generates the light of first wave length;
By fiber coupler, the light of first wave length is sent to the first multimode fibre of intelligence sensor, the light of described first wave length passes second multimode fibre of single-mode fiber to intelligence sensor;
When photodiode receives the light of described first wave length from the second multimode fibre of intelligence sensor, produce photoelectric current when described photoelectric diode is penetrated in the illumination of first wave length;
Processor is penetrated according to the illumination of first wave length the photoelectric current that photoelectric diode produces and is calculated described PH sensitive membrane to the absorbance of the light of first wave length, and according to the corresponding relation preset between pH value and absorbance, determines the pH value of current wound; And
Processor, according to the corresponding relation preset between pH value and the gradient of infection of wound, determines the gradient of infection of current wound.
9. wound infection degree monitoring method as claimed in claim 8, it is characterized in that, described binder body comprises cover layer, medicine layer and adhesive layer, and described cover layer and medicine layer are pasted, and described medicine layer and adhesive layer are pasted, wherein:
Described medicine layer is provided with for pasting bonding strip on described adhesive layer and multiple salient point comprising lysozyme, described salient point is arranged at the surface that described medicine layer and adhesive layer are pasted, the bonding strip of described medicine layer is arranged at the edge on the surface that described medicine layer and adhesive layer are pasted, and described medicine layer is a kind of adhesive structure that can tear from adhesive layer; And
Described adhesive layer is provided with multiple mesh and the bonding strip for pasting edge of wound, the bonding strip of described adhesive layer is arranged at the edge on described adhesive layer surface, when described adhesive layer and medicine layer are pasted, described salient point is embedded in described mesh, and described salient point and Wound contact are to sterilize to wound by lysozyme.
10. wound infection degree monitoring method as claimed in claim 9, it is characterized in that, the method also comprises step: according to the gradient of infection of current wound, by medicine layer described in display device reminding user to replace.
CN201510581304.6A 2015-09-12 2015-09-12 Wound infection degree monitoring system and method Pending CN105250074A (en)

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