CN103550864B - Hybrid-driven pacemaker and hybrid driving method of pacemaker electrode - Google Patents
Hybrid-driven pacemaker and hybrid driving method of pacemaker electrode Download PDFInfo
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- CN103550864B CN103550864B CN201310520450.9A CN201310520450A CN103550864B CN 103550864 B CN103550864 B CN 103550864B CN 201310520450 A CN201310520450 A CN 201310520450A CN 103550864 B CN103550864 B CN 103550864B
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Abstract
The invention discloses a hybrid-driven pacemaker and a hybrid driving method of a pacemaker electrode. According to the hybrid-driven pacemaker, mechanical energy generated by the contraction and release of an organ is converted into electric energy through a nanogenerator, the hybrid-driven pacemaker is attached to the organ, the electric energy is stored in a super capacitor, and when the pacemaker electrode needs to work, the pacemaker electrode is driven to work under the control of a control module. A battery module only supplies a power supply to the pacemaker electrode when power in the super capacitor is insufficient. Correspondingly, the hybrid driving method of the pacemaker electrode is further provided. According to the pacemaker, the service life of the battery module is greatly prolonged, and reoperation risks and economic loads caused by battery replacement to a patient are lowered.
Description
Technical field
The present invention relates to medical instruments field, be specifically related to a kind of based on nano generator combining super capacitor device and the pacemaker of rechargeable battery combination drive and the method for combination drive pacemaker electrode.
Background technology
Pacemaker, also claims pulse generator.The pacemaker that people are usually said, refers to whole pacing system.Pacing system is made up of pacemaker, pacing electrode wire and program control instrument, wherein pacemaker and pacing electrode wire implant into body.Pacemaker is made up of the circuit be arranged in can and battery.Current pacemaker mainly can be divided into cardiac pacemaker, brain pacemaker, larynx pacemaker etc.
Existing cardiac pacemaker, brain pacemaker, larynx pacemaker etc. all need to implant, and need battery to power.At present, the battery in pacemaker is generally the lithium-iodine battery be enclosed in titanium alloy casing, and when dead battery capability, needs of patients again carries out operation and could continue to use pacemaker to change battery, causes great burden to patient's body and mind and economy.
Summary of the invention
The invention provides a kind of with the pacemaker of the combination drive of nano generator combining super capacitor and rechargeable battery, in order to solve limited problem in current pacemaker battery cruising time.
To achieve these goals, the invention provides a kind of pacemaker of combination drive, comprising: nano generator, rectification circuit, super capacitor, control module, battery module and pacemaker electrode, wherein,
The mechanical force that described nano generator produces for collecting organ, and produce the alternating-current pulse signal of telecommunication;
Described rectification circuit is used for changing the signal of telecommunication that described nano generator produces into DC signal, the DC pulse signal of telecommunication that super capacitor produces for storing described rectification circuit;
Described control module is used for when the electrical potential information of pacemaker therapentic part occurs abnormal, and super capacitor described in instruction drives described pacemaker electrode to discharge to pacemaker therapentic part; When the electricity in super capacitor is not enough to drive pacemaker electrode electric discharge, described control module is used for instruction battery module and drives pacemaker electrode electric discharge.
Preferably, when described pacemaker electrode does not discharge, described control module is used for instruction super capacitor to described charging battery module.
Preferably, described control module comprises the first decision circuitry, filter circuit and mu balanced circuit, wherein,
Described first decision circuitry, for accepting the pacemaker therapentic part electrical potential information of pacemaker electrode feedback and judging whether exception, when electrical potential information occurs abnormal, instruction super capacitor exports electric energy to described filter circuit; Described first decision circuitry is also for judging whether the electricity in described super capacitor can drive pacemaker electrode to discharge, when the electricity in super capacitor is not enough to drive pacemaker electrode 6 to discharge, described first decision circuitry is used for battery module described in instruction and drives pacemaker electrode; Described first decision circuitry is also for receiving the electric quantity signal that battery module sends, and when the electricity in battery module is lower than setting limit value, described first decision circuitry is used for instruction super capacitor to described charging battery module;
The Rectified alternating current that described filter circuit is used for described super capacitor to export carries out filtering;
Described mu balanced circuit is supplied to pacemaker electrode after being used for the further voltage stabilizing of unidirectional current exported by described filter circuit and discharges to pacemaker therapentic part.
Preferably, described first decision circuitry comprises: central processor CPU, memory RAM and A/D converter, wherein,
Be transferred to after central processor CPU and memory RAM carry out storing and judge after the signal input port of described first decision circuitry receives signal after A/D converter process, according to judged result, instruction exported by signal outlet.
Preferably, described battery module comprises the second decision circuitry and rechargeable battery, and wherein, the effect of the second decision circuitry is to judge that whether electricity in rechargeable battery is lower than described setting limit value; The effect of the second decision circuitry is also the instruction that reception first decision circuitry provides, and discharges or charge to rechargeable battery.
Preferably, described second decision circuitry comprises: central processor CPU, memory RAM and A/D converter, wherein,
Be transferred to after central processor CPU and memory RAM carry out storing and judge after the signal input port of described second decision circuitry receives signal after A/D converter process, according to judged result, instruction exported by signal outlet.
Preferably, described nano generator is franklinic electricity nano generator.
Preferably, described franklinic electricity nano generator comprises: the first electrode, polymeric dielectric layer, metal nanoparticle and the second electrode, wherein, first electrode contact is arranged at the upper surface of polymeric dielectric layer, metal nanoparticle is attached to the upper surface of the second electrode, and the lower surface of polymeric dielectric layer and the second electrodes have the surface of metal nanoparticle to be oppositely arranged; When the generation deformation of franklinic electricity nano generator, described polymeric dielectric layer lower surface and described metal nanoparticle rub.
Preferably, described polymeric dielectric layer is selected from politef, polydimethylsiloxane, Kapton, aniline-formaldehyde resin thin film, polyformaldehyde thin film, ethyl cellulose film, polyamide film, melamino-formaldehyde thin film, Polyethylene Glycol succinate thin film, cellulose membrane, cellulose acetate film, 10PE27 thin film, polydiallyl phthalate thin film, regenerated fiber sponge films, elastic polyurethane body thin film, styrene-acrylonitrile copolymer copolymer film, styrene-butadiene-copolymer thin film, staple fibre thin film, poly-methyl thin film, methacrylic acid ester film, polyvinyl alcohol film, mylar, polyisobutylene thin film, polyurethane flexible sponge films, pet film, polyvinyl butyral film, phenolic resins thin film, neoprene thin film, butadiene-propylene copolymer thin film, natural rubber films, polyacrylonitrile thin film, poly-(vinylidene chloride-co-acrylonitrile) thin film or polyethylene third diphenol carbonate thin film, polystyrene, polymethyl methacrylate, Merlon or polymeric liquid crystal copolymer, polychlorobutadiene, polyacrylonitrile, poly-biphenol carbonic ester, CPPG, polyvinylidene chloride, polyethylene, polypropylene and polrvinyl chloride.
Preferably, described first electrode and/or the second electrode are metallic film.
Preferably, described metal nanoparticle is gold nano grain.
Preferably, described nano generator is piezoelectric type nano generator, and described piezoelectric type nano generator comprises the top electrode of stacked close contact from top to bottom, dielectric layer, piezoelectric layer and hearth electrode.
Preferably, described piezoelectric type nano generator is flexible structure.
Preferably, described piezoelectric layer is piezoelectric membrane or piezoelectric nano structural material.
Preferably, described super capacitor is carbon nano-tube super electric capacity.
Accordingly, the present invention also provides the method for a kind combination drive pacemaker electrode to comprise step:
Nano generator is provided;
Described nano generator is subject to the effect generation deformation of power, produces ac signal; The effect of described power is from the motion of the attached organ of described nano generator note;
Described ac signal is be stored in super capacitor after DC signal through rectifier circuit rectifies;
The electrical potential information of pacemaker electrode perception pacemaker therapentic part, and described electrical potential information is fed back to control module;
Described control module judges that whether described electrical potential information is normal, if normally, pacemaker electrode does not discharge; If abnormal, whether the electricity of control module test super capacitor can drive pacemaker electrode to discharge, if so, and the electrical energy drive pacemaker electrode electric discharge in control module instruction super capacitor; If not, the electrical energy drive pacemaker electrode electric discharge in control module directing battery module.
Preferably, described control module comprises the first decision circuitry, filter circuit and mu balanced circuit, and described control module judges that whether described electrical potential information is normal, and be specially, described first decision circuitry judges that whether described electrical potential information is normal;
Whether the electricity of control module test super capacitor can drive pacemaker electrode to discharge, and is specially, and whether the electricity of the first decision circuitry test super capacitor can drive pacemaker electrode to discharge;
Control module instruction super capacitor or battery module drive pacemaker electrode electric discharge, are specially, and the electric energy in the first decision circuitry instruction super capacitor or battery module is supplied to pacemaker electrode electric discharge after circuit and mu balanced circuit after filtering.
Preferably, also comprise step: when the electric energy in battery module is lower than setting limit value, the electric energy transmitting stored in super capacitor described in control module instruction is to battery module.
Preferably, described battery module comprises the second decision circuitry and rechargeable battery, and wherein, under the instruction of described first decision circuitry, the second decision circuitry controls described rechargeable battery and discharges to pacemaker electrode.
Preferably, the span of described setting limit value is the 50%-95% of described battery module Full Charge Capacity.
The pacemaker of combination drive provided by the invention, compared with prior art has following advantages:
In the present invention, the mechanical energy produced when transforming the attached organ of its note (as heart or diaphram) folding and unfolding by nano generator is electric energy and is stored in super capacitor, and pacemaker electrode needs under the control of control module, to drive pacemaker electrode work during work; For pacemaker electrode provides power supply when the electricity of battery module only in super capacitor is not enough.The pacemaker that relatively traditional lithium-iodine battery is powered, adopt pacemaker and the pacemaker electrode driving method of combination drive of the present invention, greatly extend the service life of battery module, reduce and change the risk of again performing the operation and financial burden that battery brings to patient.
In addition, by the control of control module, super capacitor can also be charging battery module, can extend the service life of battery module further.
Accompanying drawing explanation
Accompanying drawing is used to provide a further understanding of the present invention, and forms a part for description, is used from explanation the present invention, but is not construed as limiting the invention with detailed description of the invention one below.In the accompanying drawings:
Fig. 1 is the structural representation of combination drive pacemaker of the present invention;
Fig. 2 is the structural representation of control module in combination drive pacemaker of the present invention;
Fig. 3 is the structural representation of battery module in combination drive pacemaker of the present invention;
Fig. 4-6 is the structural representation of franklinic electricity nano generator in combination drive pacemaker of the present invention;
Fig. 7 is the structural representation of piezoelectric type nano generator in combination drive pacemaker of the present invention;
Fig. 8 is the schematic diagram of the first decision circuitry in control module;
Fig. 9 is the schematic diagram of combination drive pacemaker electrode method of the present invention.
Detailed description of the invention
For making the object, technical solutions and advantages of the present invention clearly understand, below in conjunction with specific embodiment, and with reference to accompanying drawing, the present invention is described in further detail.
The invention provides a kind of pacemaker of combination drive, can solve in prior art, pacemaker can only rely on battery powered, causes service life limited and needs to change the problems such as battery.
Fig. 1 shows the structural representation of combination drive pacemaker provided by the invention, and this pacemaker comprises: nano generator 1, rectification circuit 2, super capacitor 3, control module 4, battery module 5 and pacemaker electrode 6.
Wherein, the mechanical force that nano generator 1 produces for collecting organ, and produce the alternating-current pulse signal of telecommunication.
Rectification circuit 2 changes DC signal into for the signal of telecommunication produced by nano generator 1, the DC pulse signal of telecommunication that super capacitor 3 produces for storing rectification circuit 2.
Control module 4 is for when the electrical potential information of pacemaker therapentic part occurs abnormal, and instruction super capacitor drives pacemaker electrode 6 to discharge to pacemaker therapentic part; When the electricity in super capacitor is not enough to drive pacemaker electrode 6 to discharge, drive pacemaker electrode 6 for instruction battery module 5.
When pacemaker electrode 6 does not discharge, instruction super capacitor 3 can charge to battery module 5.
Pacemaker therapentic part described in the present invention, is specially the position needing pacemaker to carry out electric pulse stimulation, the organs such as such as heart, brain, nerve.
As an embodiment, see Fig. 2, control module 4 can comprise the first decision circuitry 7, filter circuit 8 and mu balanced circuit 9.Wherein, the first decision circuitry 7 is for accepting the pacemaker therapentic part electrical potential information of pacemaker electrode 6 feedback and judging whether exception, and when electrical potential information occurs abnormal, instruction super capacitor 3 exports electric energy to filter circuit 8; First decision circuitry 7 is also for judging whether the electricity in super capacitor 3 can drive pacemaker electrode 6 to discharge, when the electricity in super capacitor 3 is not enough to drive pacemaker electrode 6 to discharge, the first decision circuitry 7 drives pacemaker electrode 6 for instruction battery module; First decision circuitry 7 is also for receiving the electric quantity signal that battery module sends, and when the electricity in battery module is lower than setting limit value, the first decision circuitry 7 is charged for instruction super capacitor 3 pairs of battery modules 5.Filter circuit 8 carries out filtering for the Rectified alternating current exported by super capacitor 3; Mu balanced circuit 9 discharges to pacemaker therapentic part for being supplied to pacemaker electrode 6 after the further voltage stabilizing of unidirectional current that exported by filter circuit 8.
Pacemaker of the present invention, when the electricity in battery module is lower than setting limit value, control module can instruction super capacitor be charging battery module.Described setting limit value be in advance to battery module 5 set charge capacity limit value, the electricity in battery module lower than during this limit value to charging battery module, higher than during this limit value not to charging battery module.The span of described setting limit value can be the 50%-95% of battery module 5 Full Charge Capacity.
As an embodiment, see Fig. 3, battery module 5 can comprise the second decision circuitry 10 and rechargeable battery 11.Wherein, the effect of the second decision circuitry 10 is to judge that whether electricity in rechargeable battery 11 is lower than described setting limit value; The effect of the second decision circuitry 10 is also the instruction that reception first decision circuitry 7 provides, and discharges or charge to rechargeable battery 11.When pacemaker electrode 6 needs electric discharge, the electric energy of storage in super capacitor 3 is not enough, the instruction that the second decision circuitry 10 accepts the first decision circuitry 7 in control module makes rechargeable battery 11 provide driving electric energy to pacemaker electrode 6; When pacemaker electrode 6 does not need electric discharge, and when in rechargeable battery 11, electricity is lower than setting limit value, then the instruction that the second decision circuitry 10 accepts the first decision circuitry 7 in control module makes super capacitor 3 charge for rechargeable battery 11.
Introduce the structure of each several part in combination drive pacemaker of the present invention below.
Nano generator 1 can be designed to laminated structure, be attached to heart, diaphram etc. with the coated rear note of biocompatible materials can produce on the organ of motion, when the normal operation of the organ such as heart, diaphram there is deformation and impel between two of nano generator electrodes to produce the output of the alternating-current pulse signal of telecommunication in drive nano generator 1.
Nano generator 1 can be franklinic electricity nano generator, and the structure of franklinic electricity nano generator, see Fig. 4, comprising: the first electrode 13, polymeric dielectric layer 14, metal nanoparticle 15 and the second electrode 16.Concrete, the first electrode 13 contact is arranged at the upper surface 14a of polymeric dielectric layer 14.First electrode 13 and the second electrode 16 are the metallic film of conduction, and preferably, be gold thin film, the first electrode 13 is plated on the lower surface 14a of described polymeric dielectric layer 14 by vacuum sputtering and vapour deposition method.Metal nanoparticle 15 is attached to the upper surface of the second electrode 16, and the surface that the lower surface 14b of polymeric dielectric layer 14 and the second electrode 16 are attached with metal nanoparticle is oppositely arranged, and wherein, metal nanoparticle, is preferably gold nano grain.
Polymeric dielectric layer 14 can be politef, polydimethylsiloxane, Kapton, aniline-formaldehyde resin thin film, polyformaldehyde thin film, ethyl cellulose film, polyamide film, melamino-formaldehyde thin film, Polyethylene Glycol succinate thin film, cellulose membrane, cellulose acetate film, 10PE27 thin film, polydiallyl phthalate thin film, regenerated fiber sponge films, elastic polyurethane body thin film, styrene-acrylonitrile copolymer copolymer film, styrene-butadiene-copolymer thin film, staple fibre thin film, poly-methyl thin film, methacrylic acid ester film, polyvinyl alcohol film, mylar, polyisobutylene thin film, polyurethane flexible sponge films, pet film, polyvinyl butyral film, phenolic resins thin film, neoprene thin film, butadiene-propylene copolymer thin film, natural rubber films, polyacrylonitrile thin film, poly-(vinylidene chloride-co-acrylonitrile) thin film or polyethylene third diphenol carbonate thin film, polystyrene, polymethyl methacrylate, Merlon or polymeric liquid crystal copolymer, polychlorobutadiene, polyacrylonitrile, poly-biphenol carbonic ester, CPPG, polyvinylidene chloride, polyethylene, polypropylene and polrvinyl chloride etc.
Franklinic electricity nano generator is carried out encapsulate rear note and be attached to the organ surface such as heart, diaphram, when organ diastole, drive the deformation such as franklinic electricity nano generator bends, Fig. 5 shows schematic cross-section when franklinic electricity nano generator bends, when franklinic electricity nano generator bends, gold nano grain 15 can occur to rub with the surface of polymeric dielectric layer 14 and produce electrostatic charge, the generation of electrostatic charge can make the electric capacity between the first electrode 13 and the second electrode 16 change, thus makes to occur electric potential difference between the first electrode 13 and the second electrode 16.
Fig. 6 shows the schematic diagram that in the preferred embodiment of the present invention, franklinic electricity nano generator is connected with external circuit, connects an ammeter 17, to represent the external circuit that nano generator connects between two electrodes of franklinic electricity nano generator.
When the electric potential difference shown in Fig. 5 occurs, free electron flows to the high electrode of electromotive force i.e. the first electrode 13 by by external circuit by a lateral electrode i.e. the second electrode 16 that electromotive force is low, thus forms electric current at external circuit, namely in ammeter 17, has electric current to flow through.When nano generator is returned to the state as Fig. 4 from case of bending, at this moment the built-in potential between the first electrode 13 and the second electrode 16 disappears, due to the insulation characterisitic of whole franklinic electricity generator polymeric dielectric layer 14, can prevent free electron in franklinic electricity nano generator inside and, now again will produce reverse potential difference between Balanced first electrode 13 and the second electrode 16, then free electron gets back to an original lateral electrode i.e. the second electrode 16 by external circuit from the first electrode 13, thus forms reverse current in external circuit.The operation principle of Here it is franklinic electricity nano generator.
Nano generator also can adopt piezoelectric type nano generator, and the typical structure of piezoelectric type nano generator, see Fig. 7, comprises the top electrode 23 of stacked close contact from top to bottom, dielectric layer 24, piezoelectric layer 25 and hearth electrode 26.Top electrode 23 and hearth electrode 24 are preferably thin-film material, can select conventional electrode material, such as, can be selected from metal, conductive oxide and conducting polymer.Metal can be selected from gold, silver, platinum, aluminum, nickel, copper, titanium, chromium or selenium, and the alloy formed by above-mentioned metal.The material of piezoelectric layer 25 can be polymer, as PMMA (polymethyl methacrylate), PI (pi), PET (polyethylene terephthalate), PS (polystyrene) etc.The material of piezoelectric layer 25 can be any piezoelectric membrane or piezoelectric nano structural material, such as: ZnO, Pb (Zr, Ti) O
3, BaTiO
3, GaN etc. thin film, nano wire or nanometer rods etc., be preferably the nano wire of the wurtzite structure piezoelectrics such as ZnO, GaN, piezoelectric layer 25 is more preferably ZnO nanowire array, and the two ends of described nano wire are connected with piezoelectric layer 25 and hearth electrode 26 respectively.
Piezoelectric type nano generator is preferably flexible structure, piezoelectric type nano generator carries out encapsulating rear note and is attached to heart, the organ surfaces such as diaphram, when organ diastole, drive franklinic electricity nano generator to bend and to piezoelectric layer 25 apply pressure make it that deformation occur time, piezoelectric layer 25 inside can by strain generation corresponding piezoelectric field, this piezoelectric field can make the surface of top electrode and hearth electrode produce electric potential difference, and then drive the electronics of external circuit from one end electrode stream to other end electrode, thus formation electric current, until the electronics that electrode is accumulated and piezoelectric field reach balance, and when applied stress unloads time, the electric potential difference formed by piezoelectric field disappears, the electrons that one of them electrode accumulates is flowed back to by rightabout, material is thus formed a current signal exchanged.
In the present invention, rectification circuit 2 changes direct current signal into for the alternating-current pulse signal of telecommunication produced by nano generator, can be bridge rectifier.Super capacitor 3, for storing the DC signal exported from rectification circuit 2, is preferably carbon nano-tube super electric capacity.Pacemaker electrode is a pulse generator, control module control under by the electric energy transmitting in super capacitor or battery module to pulse generator, to pacemaker therapentic part apply electric pulse.Pacemaker electrode 6 can also have detection pacemaker therapentic part electrical potential information and feed back to the function of control module 4.
See Fig. 8, in control module 4, first decision circuitry 7 can comprise central processor CPU, memory RAM and A/D converter, be transferred to after central processor CPU and memory RAM carry out storing and judge after the signal input port In of the first decision circuitry receives signal after A/D converter process, according to judged result, instruction exported by signal outlet Out.The signal that signal input port In receives comprises: pacemaker therapentic part electrical potential information, the information about power of super capacitor and the information about power of battery module that pacemaker electrode returns.The signal that signal outlet Out exports comprises: whether to pacemaker electrode electric discharge, select super capacitor or battery module to pacemaker electrode electric discharge and super capacitor to charging battery module.The realization of the concrete function of the first decision circuitry 7 can be realized by write-in program in central processor CPU, memory RAM and A/D converter.
Particularly, filter circuit 8 and mu balanced circuit 9 are common circuit, and physical circuit and parameter can reasonably design as required.
In battery module 5, the second decision circuitry 10 is connected between the first decision circuitry and rechargeable battery, discharges electric energy for controlling rechargeable battery 11 to pacemaker electrode 6; Can also be used for judging whether the electricity in rechargeable battery 11 is less than setting limit value, if be less than setting limit value, the second decision circuitry 10 controls super capacitor 3 pairs of rechargeable batteries 11 and charges.In battery module 5, second decision circuitry 10 can be identical with the first decision circuitry 7 structure, second decision circuitry 10 can comprise central processor CPU, memory RAM and A/D converter, see Fig. 8, be transferred to after central processor CPU and memory RAM carry out storing and judge after the signal input port In of the second decision circuitry receives signal after A/D converter process, according to judged result, instruction exported by signal outlet Out.The signal that signal input port In receives comprises: the charging instruction of control module 4 or electric discharge instruction.The signal that signal outlet Out exports comprises: electric quantity of rechargeable battery signal; Whether rechargeable battery discharges or charging signals.The realization of the concrete function of the second decision circuitry 10 can be realized by write-in program in central processor CPU, memory RAM and A/D converter.Rechargeable battery 11 is preferably lithium ion battery.
Conventional pacemaker can be divided into cardiac pacemaker, brain pacemaker, larynx pacemaker etc.Cardiac pacemaker is that a kind of Pacing lead by contacting with heart transmits electricity irritation, finally cause whole atrium (or) device of ventricular systole, can be used for treatment acute and chronic arrhythmia, neural mediation fainted, the disease such as obstructive heart disease and obstinate type heart failure.Brain pacemaker, also known as lesions located in deep brain device, specific nerve nucleus implant electrode in brain, release high-frequency electrical stimulation, lower being overexcited of diseased nerve unit, suppress the abnormal brain nerve signal causing Parkinsonian symptoms, thus alleviate Parkinsonian cardinal symptom: to tremble, stiff and bradykinesia, especially center line symptom has good improvement result, as started to walk and standing up difficulty etc.Larynx pacemaker, its main part is a pulse generator, and this implantable pulse generator can make the patient of laryngeal muscles bilateral paralysis speak normally and breathe.No matter which kind of pacemaker, all needs to carry out electricity irritation at power drives pulse generator to pacemaker therapentic part, in existing pacemaker, adopts lithium ion battery as power supply, with in pulse generator, control device and pacemaker electrode together implantable bioartificial body.Because the electricity of lithium ion battery is limited, when battery electric quantity is not enough to drive pacemaker electrode, pacemaker cisco unity malfunction, to the health of patient even life cause great threat, need again to perform the operation and carry out battery altering, not only cause financial burden to patient, and the physical and mental health of patient can be affected.
Adopt the pacemaker of combination drive of the present invention, mainly make use of nano generator and collect the contraction of patient organ's such as heart etc. and the energy of diastole, changed into electric energy to drive pacemaker electrode.This pacemaker also comprises battery module simultaneously, and as stand-by power supply, when the electricity stored in super capacitor is not enough to drive pacemaker electrode, battery module will as power drives pacemaker electrode.The use of the pacemaker of combination drive of the present invention solves the problem that existing pacemaker needs to change battery, can the work of long-time stable.
Below for cardiac pacemaker, composition graphs 1, specifically introduces the work process of the pacemaker of combination drive of the present invention, when nano generator 1 is subject to generation current after as mechanical energy when heart beating or contraction of diaphragm and diastole.Because the electric current produced like this is alternating current, the alternating current therefore by rectification circuit 2, nano generator 1 being produced becomes unidirectional current.By the electric current after rectification, super capacitor 3 is charged.When delaying or overrunning appearred in the heart beating of patient, pacemaker was started working, and now super capacitor 3 inputs electric energy to pacemaker electrode 6, drove its work; When the heart beating of patient is normal, the sensor feedback signal in pacemaker electrode 6, to control module 4, controls super capacitor 3 and makes super capacitor 3 not provide electric energy to pacemaker electrode 6, but charge to battery module 5 by control module 4.When the work of pacemaker long period, stored by super capacitor 3, energy temporarily cannot meet pacemaker, control module 4 directing battery module 5 is started working and is provided electric energy to pacemaker electrode 6, thus has ensured that heart device of fighting can work long hours.
No matter nano generator 1 adopts piezoelectric type nano generator or franklinic electricity nano generator, and preferably, nano generator is flexible device.Particularly franklinic electricity nano generator can adopt high molecular polymer to make, and makes nano generator entirety be flexible structure.The nano generator 1 of flexibility is attached to heart or diaphram surface, the heart surface Curvature varying utilizing the diastole of heart or diaphram and contraction to produce makes nano generator, along with the change of heart, corresponding bending change occur, thus drive free electron to flow in peripheral circuit in two electrodes generation electric potential differences of electromotor, then change into the applicable electric current of energy-storage travelling wave tube charging, or cardiac pacemaker electrodes work can be driven through rectification circuit.Brain pacemaker is identical with the operation principle of cardiac pacemaker with the operation principle of larynx pacemaker.
Accordingly, the present invention also provides a kind of method of combination drive pacemaker electrode, and flow chart shown in Figure 9, comprises step:
Nano generator is provided;
Described nano generator is subject to the effect generation deformation of power, produces ac signal AC; The effect of described power is from the motion of the attached organ of described nano generator note;
Described ac signal AC is be stored in super capacitor after DC signal DC through rectifier circuit rectifies;
The electrical potential information EF of pacemaker electrode perception pacemaker therapentic part, and described electrical potential information EF is fed back to control module;
Described control module judges that whether described electrical potential information EF is normal, if normally, pacemaker electrode does not discharge; If abnormal, whether the electricity of control module test super capacitor can drive pacemaker electrode to discharge, and if so, the electric energy Q (providing electric current I) in control module instruction super capacitor drives pacemaker electrode to discharge; If not, the electric energy Q-out (providing electric current I) in control module directing battery module drives pacemaker electrode to discharge.
The method of combination drive pacemaker electrode provided by the invention, the energy of main dependence nano generator catcher official career movable property life is changed into electrical power storage in ultracapacitor, for pacemaker electrode provides power supply, when the electricity in super capacitor is not enough to drive pacemaker electrode, battery module provides power supply for pacemaker electrode, realizes combination drive pacemaker electrode.Method advantage of the present invention is, the main electrical power storage relying on nano generator generation is powered in super capacitor, and battery module supplementing just when the electricity of super capacitor is not enough, therefore, battery module can use for a long time.
Preferably, also comprise step: when the electric energy in battery module is lower than setting limit value, the electric energy Q stored in super capacitor described in control module instruction is transferred to battery module.This step enables battery module obtain electric energy from super capacitor, extends the life-span of battery module further.The span of described setting limit value can be the 50%-95% of battery module 5 Full Charge Capacity.
Preferably, control module comprises the first decision circuitry, filter circuit and mu balanced circuit, and described control module judges that whether described electrical potential information is normal, and be specially, described first decision circuitry judges that whether described electrical potential information is normal.Whether the electricity of control module test super capacitor can drive pacemaker electrode to discharge, and is specially, and whether the electricity of the first decision circuitry test super capacitor can drive pacemaker electrode to discharge.Control module instruction super capacitor or battery module drive pacemaker electrode electric discharge, are specially, and the electric energy in the first decision circuitry instruction super capacitor or battery module is supplied to pacemaker electrode electric discharge after circuit and mu balanced circuit after filtering.Control module directing battery module drive pacemaker electrode discharges, and is specially, described first decision circuitry directing battery module drive pacemaker electrode electric discharge.
Preferably, described battery module comprises the second decision circuitry and rechargeable battery.Wherein, under the instruction of described first decision circuitry, the second decision circuitry controls described rechargeable battery and discharges to pacemaker electrode.
Preferably, under the instruction of described first decision circuitry, the second decision circuitry tests the whether satisfied setting limit value of electricity of described rechargeable battery, when not meeting setting limit value, second decision circuitry returns the request needing charging to the first decision circuitry, the electric energy transmitting stored in super capacitor described in described first decision circuitry instruction gives described rechargeable battery.
Above-described specific embodiment; object of the present invention, technical scheme and beneficial effect are further described; be understood that; the foregoing is only specific embodiments of the invention; be not limited to the present invention; within the spirit and principles in the present invention all, any amendment made, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (18)
1. a pacemaker for combination drive, is characterized in that, comprising: nano generator, rectification circuit, super capacitor, control module, battery module and pacemaker electrode, wherein,
The mechanical force that described nano generator produces for collecting organ, and produce the alternating-current pulse signal of telecommunication;
Described rectification circuit is used for changing the signal of telecommunication that described nano generator produces into DC signal, the DC pulse signal of telecommunication that super capacitor produces for storing described rectification circuit;
Described control module is used for when the electrical potential information of pacemaker therapentic part occurs abnormal, and super capacitor described in instruction drives described pacemaker electrode to discharge to pacemaker therapentic part; When the electricity in super capacitor is not enough to drive pacemaker electrode electric discharge, described control module is used for instruction battery module and drives pacemaker electrode electric discharge, and described control module comprises the first decision circuitry, filter circuit and mu balanced circuit, wherein,
Described first decision circuitry, for accepting the pacemaker therapentic part electrical potential information of pacemaker electrode feedback and judging whether exception, when electrical potential information occurs abnormal, instruction super capacitor exports electric energy to described filter circuit; Described first decision circuitry is also for judging whether the electricity in described super capacitor can drive pacemaker electrode to discharge, when the electricity in super capacitor is not enough to drive pacemaker electrode electric discharge, described first decision circuitry is used for battery module described in instruction and drives pacemaker electrode; Described first decision circuitry is also for receiving the electric quantity signal that battery module sends, and when the electricity in battery module is lower than setting limit value, described first decision circuitry is used for instruction super capacitor to described charging battery module;
The Rectified alternating current that described filter circuit is used for described super capacitor to export carries out filtering;
Described mu balanced circuit is supplied to pacemaker electrode after being used for the further voltage stabilizing of unidirectional current exported by described filter circuit and discharges to pacemaker therapentic part.
2. pacemaker according to claim 1, is characterized in that, when described pacemaker electrode does not discharge, described control module is used for instruction super capacitor to described charging battery module.
3. pacemaker according to claim 1, is characterized in that, described first decision circuitry comprises: central processor CPU, memory RAM and A/D converter, wherein,
Be transferred to after central processor CPU and memory RAM carry out storing and judge after the signal input port of described first decision circuitry receives signal after A/D converter process, according to judged result, instruction exported by signal outlet.
4. pacemaker according to claim 1 and 2, is characterized in that, described battery module comprises the second decision circuitry and rechargeable battery, and wherein, the effect of the second decision circuitry is to judge that whether electricity in rechargeable battery is lower than described setting limit value; The effect of the second decision circuitry is also the instruction that reception first decision circuitry provides, and discharges or charge to rechargeable battery.
5. pacemaker according to claim 4, is characterized in that, described second decision circuitry comprises: central processor CPU, memory RAM and A/D converter, wherein,
Be transferred to after central processor CPU and memory RAM carry out storing and judge after the signal input port of described second decision circuitry receives signal after A/D converter process, according to judged result, instruction exported by signal outlet.
6. the pacemaker according to any one of claim 1-3 and claim 5, is characterized in that, described nano generator is franklinic electricity nano generator.
7. pacemaker according to claim 6, it is characterized in that, described franklinic electricity nano generator comprises: the first electrode, polymeric dielectric layer, metal nanoparticle and the second electrode, wherein, first electrode contact is arranged at the upper surface of polymeric dielectric layer, metal nanoparticle is attached to the upper surface of the second electrode, and the lower surface of polymeric dielectric layer and the second electrodes have the surface of metal nanoparticle to be oppositely arranged; When the generation deformation of franklinic electricity nano generator, described polymeric dielectric layer lower surface and described metal nanoparticle rub.
8. pacemaker according to claim 7, is characterized in that, described polymeric dielectric layer is selected from one or more the mixture in llowing group of materials: politef, polydimethylsiloxane, Kapton, aniline-formaldehyde resin thin film, ethyl cellulose film, polyamide film, melamino-formaldehyde thin film, Polyethylene Glycol succinate thin film, cellulose acetate film, 10PE27 thin film, polydiallyl phthalate thin film, regenerated fiber sponge films, elastic polyurethane body thin film, styrene-acrylonitrile copolymer copolymer film, styrene-butadiene-copolymer thin film, poly-methyl thin film, methacrylic acid ester film, polyvinyl alcohol film, mylar, polyisobutylene thin film, polyurethane flexible sponge films, pet film, polyvinyl butyral film, phenolic resins thin film, neoprene thin film, butadiene-propylene copolymer thin film, natural rubber films, polyacrylonitrile thin film, poly-(vinylidene chloride-co-acrylonitrile) thin film or polyethylene third diphenol carbonate thin film, polystyrene, polymethyl methacrylate, Merlon or polymeric liquid crystal copolymer, polychlorobutadiene, polyacrylonitrile, poly-biphenol carbonic ester, CPPG, polyvinylidene chloride, polyethylene, polypropylene and polrvinyl chloride.
9. the pacemaker according to claim 7 or 8, is characterized in that, described first electrode and/or the second electrode are metallic film.
10. pacemaker according to claim 7, is characterized in that, described metal nanoparticle is gold nano grain.
11. pacemakers according to any one of claim 1-3 and claim 5, it is characterized in that, described nano generator is piezoelectric type nano generator, and described piezoelectric type nano generator comprises the top electrode of stacked close contact from top to bottom, dielectric layer, piezoelectric layer and hearth electrode.
12. pacemakers according to claim 11, is characterized in that, described piezoelectric type nano generator is flexible structure.
13. pacemakers according to claim 11, is characterized in that, described piezoelectric layer is piezoelectric membrane or piezoelectric nano structural material.
14. according to claim 1-3,5,7-8,10 and 12-13 according to any one of pacemaker, it is characterized in that, described super capacitor is carbon nano-tube super electric capacity.
The method of 15. 1 kinds of combination drive pacemaker electrodes, is characterized in that, comprises step:
Nano generator is provided;
Described nano generator is subject to the effect generation deformation of power, produces ac signal; The effect of described power is from the motion of the attached organ of described nano generator note;
Described ac signal is be stored in super capacitor after DC signal through rectifier circuit rectifies;
The electrical potential information of pacemaker electrode perception pacemaker therapentic part, and described electrical potential information is fed back to control module;
Described control module judges that whether described electrical potential information is normal, if normally, pacemaker electrode does not discharge; If abnormal, whether the electricity of control module test super capacitor can drive pacemaker electrode to discharge, if so, and the electrical energy drive pacemaker electrode electric discharge in control module instruction super capacitor; If not, the electrical energy drive pacemaker electrode electric discharge in control module directing battery module, wherein, described control module comprises the first decision circuitry, filter circuit and mu balanced circuit,
Described control module judges that whether described electrical potential information is normal, and be specially, described first decision circuitry judges that whether described electrical potential information is normal;
Whether the electricity of control module test super capacitor can drive pacemaker electrode to discharge, and is specially, and whether the electricity of the first decision circuitry test super capacitor can drive pacemaker electrode to discharge;
Control module instruction super capacitor or battery module drive pacemaker electrode electric discharge, are specially, and the electric energy in the first decision circuitry instruction super capacitor or battery module is supplied to pacemaker electrode electric discharge after circuit and mu balanced circuit after filtering.
16. methods according to claim 15, is characterized in that, also comprise step: when the electric energy in battery module is lower than setting limit value, the electric energy transmitting stored in super capacitor described in control module instruction is to battery module.
17. methods according to claim 16, is characterized in that, described battery module comprises the second decision circuitry and rechargeable battery, and wherein, under the instruction of described first decision circuitry, the second decision circuitry controls described rechargeable battery and discharges to pacemaker electrode.
18. methods according to claim 16 or 17, it is characterized in that, the span of described setting limit value is the 50%-95% of described battery module Full Charge Capacity.
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