WO2021106504A1

WO2021106504A1 - Transfer film, transfer layered body, and transfer method for transfer layered body

Info

Publication number: WO2021106504A1
Application number: PCT/JP2020/041066
Authority: WO
Inventors: 勇輝室井
Original assignee: 凸版印刷株式会社
Priority date: 2019-11-27
Filing date: 2020-11-02
Publication date: 2021-06-03
Also published as: JP2021083683A

Abstract

In the present invention, a transfer layer (11) is configured so that the thickness thereof is 50-3000nm, the pressing amount at the time of rupture in a piercing test is at least 0.6mm, and the load when pressed 0.4mm in the piercing test is 20-250mN.

Description

Transfer film, transfer laminate, and transfer method of transfer laminate

The present invention relates to a transfer film, a transfer laminate, and a transfer method for the transfer laminate.

In recent years, a method of transferring a transfer laminate to the surface of skin or an organ has attracted attention for medical and cosmetic purposes. Such a transfer laminate has a structure in which a transfer film layer (transfer layer) is laminated on, for example, a base material layer, and the transfer laminate is provided so that the transfer layer and the transfer target come into contact with each other. After the arrangement, the transfer layer is transferred to the transferee by peeling off the base material layer for use. The transferability of the transfer layer to the skin and organ surfaces is obtained by the thin transfer layer. In Patent Document 1, a transfer film having a film thickness of several tens of nm to several μm is used as the transfer layer. Patent Document 2 proposes a laminate in which a transfer film is formed on a supporting base material.

International Publication No. 2014/058066 JP-A-2017-19116

The thinner the transfer layer, the easier it is to tear, and wrinkles and twists are more likely to occur during transfer, which reduces operability. Transfer defects such as tears, wrinkles, and twists cause discomfort in appearance and fit.

An object of the present invention is to provide a transfer film, a transfer laminate, and a transfer method thereof, which can improve adhesion without deteriorating operability during transfer.

The transfer film according to one aspect of the present invention is a transfer film having a thickness of 50 nm or more and 3000 nm or less, and has an indentation amount at break of 0.6 mm or more in the puncture test, and 0. The load when pushing 4 mm is 20 mN or more and 250 mN or less.

The transfer laminate according to another aspect of the present invention includes a transfer film and a base material layer laminated on at least one surface of the transfer film, and the base material layer includes a part or all of the base material layer. It is composed of any of liquid-absorbent films, woven fabrics, knitted fabrics, non-woven fabrics, and paper.

The transfer method of the transfer laminate according to another aspect of the present invention includes an arrangement step of arranging the transfer laminate on the transfer target so that the transfer film side faces the transfer target, and a liquid in the base material layer. It includes a liquid absorbing step of absorbing the body and a transfer step of pressing the base material layer side of the transfer laminate to transfer the transfer film to the transfer target.

According to the present invention, the adhesion can be improved without lowering the operability at the time of transfer.

It is sectional drawing which shows the laminated body for transfer. It is the schematic of the piercing test. It is sectional drawing which shows the laminated body for transfer which provided the protective layer.

Next, an embodiment of the present invention will be described with reference to the drawings.
Here, the drawings are schematic, and the relationship between the thickness and the plane dimensions, the ratio of the thickness of each layer, and the like are different from the actual ones. Further, the embodiments shown below exemplify a configuration for embodying the technical idea of the present invention, and the technical idea of the present invention describes the materials, shapes, structures, etc. of the constituent parts as follows. It is not something that is specific to something. The technical idea of the present invention may be modified in various ways within the technical scope specified by the claims stated in the claims.

(Laminate for transfer)
The transfer laminate 1 of the present embodiment shown in FIG. 1 has a structure in which a transfer layer 11 and a base material layer 12 are laminated. Hereinafter, each layer constituting the transfer laminate 1 will be described in detail.

(Transfer layer)
The transfer layer 11 (transfer film) is formed on one surface of the base material layer 12. The transfer layer 11 is arranged on the transfer material (arrangement step), the liquid material is absorbed by the base material layer 12 (liquid absorption step), and the base material layer 12 side of the transfer laminate 1 is pressed. It is transferred to the transfer target (transfer step).
The thickness of the transfer layer 11 is 50 nm or more and 3000 nm (3 μm) or less from the viewpoint of followability, permeability during liquid absorption, and the like. If it is less than 50 nm, it is easily torn and difficult to manufacture and handle, and if it is 3000 nm or more, the followability to the transferred body may be lowered. The thickness of the transfer layer 11 is more preferably 100 nm or more and 500 nm or less, and further preferably 120 nm or more and 200 nm or less.

The thickness of the transfer layer 11 may be directly measured with a film thickness meter or the like, or the average thickness may be converted from the weight per unit area. If there is unevenness or a gradient in thickness, the average thickness converted from the weight per unit area and the density is adopted. The weight of the transfer layer 11 can be measured from a sample cut into an area shape of ^{, for example, about 100 cm 2.} Weight of the transfer layer 11 is, for example, the density of the material constituting the transfer layer 11 is equal to 1 g / cm ³ or more 1.5 g / cm ³ or less, is 0.05 g / ^{m 2} or more 4.5 g / ^{m 2} or less Is preferable.

The amount of pushing of the transfer layer 11 at break in the piercing test is 0.6 mm or more. When the amount of pressing of the transfer layer 11 at break is less than 0.6 mm, the transfer layer 11 is not easily deformed, the followability to the transferred body is lowered, and the adhesion is difficult to be obtained. In addition, it is easily torn during use and operability is reduced. The amount of the transfer layer 11 pushed in at break is more preferably 0.8 mm or more. The upper limit of the pressing amount of the transfer layer 11 is not particularly set, but if it is excessively high, the film strength of the transfer layer 11 becomes low, so that it is preferably about 2 mm or less.

The load when the transfer layer 11 is pushed in by 0.4 mm in the piercing test is 20 mN or more and 250 mN or less. If the load of the transfer layer 11 when pressed by 0.4 mm is less than 20 mN, the transfer layer 11 is easily torn and the operability is deteriorated. When the load of the transfer layer 11 when pressed by 0.4 mm exceeds 250 mN, the transfer layer 11 is less likely to be deformed, the followability to the transferred object is lowered, and the adhesion is difficult to obtain. The load of the transfer layer 11 when pressed by 0.4 mm is more preferably 40 mN or more and 120 mN or less.

The load at break of the transfer layer 11 in the puncture test is 25 mN or more and 800 mN or less. When the load at break of the transfer layer 11 is less than 25 mN, the transfer layer 11 is easily torn when a force is applied from the outside, and the operability is deteriorated. When the load at break of the transfer layer 11 exceeds 800 mN, the transfer layer 11 is less likely to be deformed, the followability to the transferred body is lowered, and the adhesion is difficult to be obtained. The load at break of the transfer layer 11 is more preferably 40 mN or more and 400 mN or less.

The piercing test in the present invention is carried out by the following method, and the indentation amount at break, the load at 0.4 mm indentation, and the indentation amount at break are measured. As shown in FIG. 2, a test piece of the transfer layer 11 having a predetermined shape (for example, 2 cm × 2 cm) is provided by using a jig so that the test portion 102 of the transfer layer 11 exists independently in a circular shape having a diameter of 6 mm. It is fixed by the fixing portion 101. The jig can be held so that the transfer layer 11 does not slip during the test, and the jig itself is not deformed during the test. The fixed test piece is adjusted in the standard temperature / humidity state 2 (temperature 23 ± 2 ° C., relative humidity (50 ± 10)%) specified in JIS K7100 after adjusting the state of the test piece for 16 hours or more. Test in the same environment as.

In the test, an indenter on a cylinder with a diameter of 3 mm was placed at a test speed of 10 ± 1 mm / min so that the central piercing portion 103 of the circular test portion 102 in which the transfer layer 11 was present alone was concentric with the test portion 102. Measure the load until the indenter penetrates after piercing. As the compression tester used for the test, a tester conforming to JIS B 7721 class 0.5 (for example, EZTest series manufactured by Shimadzu Corporation) is used. The number of test pieces is 5 or more, and the average value is calculated.

The indentation amount of the puncture test in the present invention refers to the amount of movement of the indenter from the position where the indenter touches the transfer layer 11. The breaking load of the transfer layer 11 refers to the maximum value of the load when the indenter penetrates or breaks through the transfer layer 11 in the puncture test. The pushing amount of the transfer layer 11 at the time of breaking refers to the pushing amount when the load is maximized at the time of breaking.
The breaking load, breaking pushing amount, and 0.4 mm pushing load of the transfer layer 11 can be adjusted by the type and molecular weight of the material forming the transfer layer 11, the thickness of the transfer layer 11, and the like.

The material constituting the transfer layer 11 is not particularly limited. Examples of the material of the transfer layer 11 include polyesters such as polylactic acid, polyglycolic acid, polycaprolactone and polydioxanone, polyolefins such as polyethylene and polypropylene, polyvinyl alcohol, polyamide, polyimide, polytetrafluoroethylene, polystyrene and poly (meth) acrylic. Acids, polyurethanes, polyvinyl acetates, polyvinyl chlorides, polyvinylidene chlorides, polysiloxanes, modified products and copolymers thereof, polysaccharides such as cellulose, hyaluronic acid, chitosan, proteins such as casein and fibroin, and these. Modified products and copolymers of the above can be used. These materials may be used alone or in combination of two or more.

The molecular structure of the material forming the transfer layer 11 makes it possible to adjust the load at break, the push-in amount at break, and the push-in load of 0.4 mm.
When a material containing a single bond, an ether bond, an ester bond, etc. is used in the main chain, the flexibility is increased, so that the molecule is easily stretched, the transfer layer 11 is also easily stretched, and the amount of indentation at break can be increased. Become. Examples of the material containing a single bond, an ether bond, an ester bond, etc. in the main chain include chain polyolefin, polyester, and polysaccharide.

Further, if a material containing a ring structure, an unsaturated bond or the like in the main chain is used, the transfer layer 11 becomes rigid and the load at break can be increased. Examples of materials containing a ring structure, an unsaturated bond, etc. in the main chain include polyester, polyimide, polyamide, polyurethane, polycycloolefin, and polysaccharides.
In addition, if a material containing a functional group that easily interacts with each other such as a hydrogen bond between molecules such as a hydroxy group, a carboxy group, an amide bond, and a urethane bond is used, the strength becomes high and the load at break and the amount of indentation at break are increased. growing. Examples of materials containing functional groups that easily interact with each other include polyvinyl alcohol, polyamide, polyurethane, and polysaccharides.

Furthermore, as the molecular weight increases, the transfer layer 11 becomes more resistant to stretching, and the amount of indentation at break and the load at break increase. Although it depends on the type of material, it is preferable that the weight average molecular weight is 80,000 or more and 500,000 or less. As described above, the thinner the transfer layer 11, the easier it is to follow the transferred body and the better the adhesion, but the easier it is to tear and the lower the operability. On the other hand, when the thickness of the transfer layer 11 becomes high, the film strength is easily obtained and it is difficult to tear, but there is a possibility that the adhesion that reduces the followability to the transferred body cannot be obtained. These adjustments can be appropriately selected depending on the adhesion of the transfer layer 11, the operability at the time of use, the preparation conditions, and the like.

The transfer layer 11 may contain a functional substance that exerts a predetermined function on the transferred body, such as skin and organs. Functional substances include, for example, pigments and high refractive index materials for adjusting optical properties, low refractive index materials, light absorbers and modifiers and conductive materials for adjusting wettability, moisturizing creams, and beauty essences. Examples thereof include cosmetics or cosmetic ingredients, pigments, drugs, enzymes and the like used for skin care such as. The functional substance may be used alone or in combination of two or more.
The transfer layer 11 may have a single-layer structure composed of a single layer, or may have a multi-layer structure composed of two or more layers.

(Base layer)
The base material layer 12 is formed so as to be in contact with the transfer layer 11 on one surface, and is scratched or torn due to contact with a transfer layer 11 other than the transferred body during production, distribution, and use of the transfer laminate 1. Plays a role in preventing. Further, when the transfer layer 11 is transferred, it has a role as a handle of the transfer laminate 1. Further, when the transfer layer 11 is transferred to the transfer target, the base material layer 12 is peeled off from the transfer layer 11.

The base material layer 12 has a liquid absorbing property. The liquid material to be absorbed is supplied to the transfer laminate 1 when the transfer layer 11 is transferred to the transfer target. The liquid material is not particularly limited as long as it is a fluid that permeates the base material layer 12. The liquid contains, for example, at least one of water, alcohol, and oil. When the transferred body is the skin of a living body, the liquid body is derived from, for example, water, alcohols, lotions, emulsions, cosmetic creams, ointments, oils, lotions, and mixtures thereof, and the use of the transfer layer 11 and the like. It is appropriately selected according to.

The material of the base material layer 12 is not particularly limited, and a material that can form the base material layer 12 having liquid absorption property may be appropriately selected and used. In order to accurately develop the liquid absorbency in the base material layer 12, at least a part thereof is composed of any of a liquid absorbable film, a woven fabric, a knitted fabric, a non-woven fabric, and paper. Is preferable.
Materials for the above-mentioned liquid-absorbent film include polyester, polyolefin, polyamide, polyimide, polyvinyl alcohol, polyurethane, polyvinylidene chloride, polyvinyl chloride, polyvinylidene chloride, polycarbonate, acrylic resin, polysiloxanes, cellulose, casein and the like. Examples include various proteins, rubbers, modified products of these high molecular compounds, copolymers and mixtures. The liquid-absorbent film may be a film that has been subjected to processing such as embossing, drilling, and porosity by foaming or the like.

The fibers constituting the woven fabric, knitted fabric, and non-woven fabric include, for example, natural fibers such as cotton, linen, silk, and wool, recycled fibers such as rayon and cupra, semi-synthetic fibers such as acetate, polyamide, polyester, polyethylene, and polypropylene. Examples thereof include synthetic fibers such as polyurethane and polyacrylic acid. The base material layer 12 may be composed of one type of fiber or may be composed of two or more types of fibers.
The basis weight of the base material layer 12 is 3 g / m ² or more and 200 g / m ² or less. Within this range, it absorbs moisture appropriately and easily peels off from the transfer layer 11. If the basis weight of ^{the base material layer 12 is less than 3 g / m 2} , the base material layer 12 is easily broken and difficult to handle, and ^{if it exceeds 200 g / m 2} , excessive liquid absorption is required. The basis weight of the base material layer 12 is more preferably ^{10 g / m 2} or more and 100 g / m ^{2 or less.}

(Protective layer)
Further, as in the transfer laminate 2 shown in FIG. 3, the protective layer 13 may be provided on the surface of the transfer layer 11 opposite to the base material layer 12.
By configuring the protective layer 13 like the transfer laminate 2, it is possible to prevent the surface of the transfer layer 11 on the protective layer 13 side from being scratched or torn due to contact with other than the transferred body. As the protective layer 13, a porous base material, a resin sheet having no gap inside, a metal foil, or the like can be used. As the porous base material, the material exemplified in the base material layer 12 can be used. Examples of the resin sheet include polyester resin, polyamide resin, polyimide resin, polyolefin resin, polystyrene resin, poly (meth) acrylic acid resin, polyurethane resin, polyvinyl alcohol, and a stretched or unstretched film of a copolymer thereof. Can be used. As the material of the metal foil, aluminum, aluminum alloy, stainless steel, oxygen-free copper, tough pitch copper, phosphor deoxidized copper, brass, phosphor bronze, electrolytic copper, nickel, iron-nickel alloy, titanium and the like can be used. The protective layer 13 may be composed of a single layer, or may be composed of a plurality of layers of two or more layers.
When transferring to the transfer target, the transfer laminate 2 is used by peeling the protective layer 13 from the transfer layer 11 before arranging it on the transfer target.

(Manufacturing method of laminate for transfer)
Hereinafter, the method for producing the above-mentioned transfer laminate 1 will be described.
Examples of the method for producing the transfer laminate 1 include the following steps (1-1) to (1-2).
(1-1) A step of forming the transfer layer 11 on the surface of the film-forming substrate.
(1-2) A step of transferring the transfer layer 11 formed on the film-forming substrate to the substrate layer 12.

Process (1-1)
As a method for forming a thin film, a melt extrusion method and a solution casting method are generally known. In the melt extrusion method, the melted material is extruded by an inflation method, a T-die extrusion method, or the like to form a thin film. In the solution casting method, the coating liquid in which the material is dissolved is formed into a thin film, and then the solution is evaporated.

In the present invention, the transfer layer 11 is formed by applying a solution in which the material of the transfer layer 11 is dissolved on the film-forming base material and drying the solvent. As the film-forming base material, a resin sheet composed of a thermoplastic resin, a thermosetting resin, or the like is used. A resin sheet made of a material that can be released and dissolved by water or a solvent may be used. The coating method of the transfer layer 11 is not particularly limited, and examples thereof include a gravure coat, a reverse gravure coat, a roll coat, a reverse roll coat, a die coat, a bar coat, a kiss coat, a comma coat, a curtain coat, a spin coat, and a spray coat. ..

Process (1-2)
The base material layer 12 is arranged on the surface of the transfer layer 11 on the film-forming base material opposite to the film-forming base material, and the transfer layer 11 is transferred from the film-forming base material to the base material layer 12. As the transfer method, a known transfer method such as a method using peeling by suction or a method using a sacrificial film is used.
By the above steps (1-1) to (1-2), the transfer laminate 1 is obtained. The method for producing the transfer laminate 1 is not limited to the method in which steps (1-1) to (1-2) are sequentially performed. For example, if necessary, the outer shape of the transfer laminate 1 may be adjusted to a desired shape by a method such as die cutting. After the step (1-2), the protective layer 13 may be laminated on the surface of the transfer layer 11 opposite to the base material layer 12.

(Method of transferring the transfer layer to the transfer target)
Hereinafter, the method of transferring the transfer layer 11 to the transfer target will be described.
Examples of the transfer method of the transfer layer 11 include the methods of the following steps (2-1) to (2-3).
(2-1) A step of supplying a liquid material to a transfer portion of the transfer layer 11 in the transfer body.
(2-2) A step of arranging the transfer laminate 1 on the transfer target so that the transfer layer 11 side faces the transfer target.
(2-3) A step of peeling the base material layer 12 from the transfer layer 11.

Process (2-1)
The liquid material is supplied to the transfer portion of the transfer layer 11 in the transfer body. The liquid material to be supplied may be absorbed by the base material layer 12, and water, lotion, massage oil, cream or the like may be used according to the intended use.
Process (2-2)
The transfer laminate 1 is arranged on the transfer target so that the transfer layer 11 side faces the transfer target. By pressing the transfer laminate 1 from the base material layer 12 side, the transfer layer 11 can be transferred to the transfer target.

Process (2-3)
The base material layer 12 is peeled from the transfer layer 11. With the transfer laminate of the present invention, the base material layer 12 can be easily peeled off from the transfer layer 11. The peeling may be performed from the outer peripheral portion of the base material layer 12 or from the notch 121.
By the above steps (2-1) to (2-3), the transfer layer 11 can be transferred to the transfer target. The method of transferring the transfer layer 11 to the transfer target is not limited to the method of sequentially performing steps (2-1) to (2-3). For example, instead of the step (2-1), the liquid material may be supplied from the base material layer 12 side of the transfer laminate 1 before the pressing in the step (2-2).

Hereinafter, the details of the present invention will be described with reference to Examples, but the present invention is not limited to the following description.
(Material used)
The materials used in Examples and Comparative Examples are shown.
(Transfer layer 11)
Transfer Material A-1: Poly-DL-Lactic Acid (manufactured by Musashino Chemical Laboratory, weight average molecular weight 100,000)
Transfer material A-2: Poly-DL-lactic acid (manufactured by Musashino Chemical Laboratory, weight average molecular weight 350,000)
Transfer Material A-3: Cellulose Acetate Propionate (manufactured by Eastman Chemical, number average molecular weight 75,000)
Transfer material A-4: Polyvinyl alcohol (manufactured by Mitsubishi Chemical, weight average molecular weight 100,000)

(Base material layer 12)
Base material B-1: Pulp-based non-woven fabric (preparation of laminate 1 for transfer)
A solution prepared by selecting a solvent so that each resin dissolves the transfer materials A-1 to A-4 on the polypropylene film as the base material for film formation is coated with a gravure coat, and the transfer layer 11 is predetermined. The transfer layer 11 was formed so as to have a thickness. Next, the base material B-1 was laminated on the transfer layer 11 as a base material layer, and the film-forming base material was peeled off to prepare a transfer laminate 1.

(Evaluation method)
Evaluation was performed by the following method. The evaluation results are shown in Table 2.
(Evaluation of operability)
In Examples 1 to 11 and Comparative Examples 1 to 4, 250 μL of water equivalent to the amount of water absorbed was supplied as a supply liquid to human skin as a transfer substance, and the water was lightly stretched with a finger. Then, the transfer laminate was placed on the skin so that the transfer layer and the skin faced each other (placement step). At this time, water is absorbed into the base material layer via the transfer layer (liquid absorption step). Next, for each of the Examples and Comparative Examples, the transfer laminate was pressed from the substrate layer side with a load of 3N for 3 seconds, and then the substrate layer was peeled off from the transfer layer while being supported by the fingers from the corners on the skin. The transfer layer was transferred to (transfer step). After the base material layer was peeled off, the transfer layer on the skin was visually observed. The evaluation was performed according to the following criteria, and evaluation C was regarded as unsuitable.

"A": Of the 5 samples, 0 samples had tears, wrinkles, or twists in the transfer layer during the transfer process.
"B": Of the five samples, one or two samples have tears, wrinkles, or twists in the transfer layer during the transfer process.
"C": Of the five samples, three or more samples had tears, wrinkles, or twists in the transfer layer during the transfer process, or one or more samples were not transferred to the skin.

(Evaluation of adhesion)
For Examples 1 to 11 and Comparative Examples 1 to 4, the transfer layer was transferred to the skin in the same manner as in the evaluation of operability. Five minutes after the transfer, the transfer layer was touched with a finger to evaluate the adhesion state. The evaluation was performed according to the following criteria, and evaluation C was regarded as unsuitable.
"A": Of the 5 samples, 0 were touched with a finger and peeled off from the skin or moved on the skin.
"B": Of the five specimens, one or two specimens were touched with a finger and peeled off from the skin or moved on the skin.
"C": Of the 5 samples, 3 or more samples were peeled off from the skin or moved on the skin by touching with a finger.

As shown in Table 2, in Examples 1 to 11, the adhesion could be improved without tearing during use or deteriorating operability during transfer. On the other hand, in Comparative Examples 1 and 3, tears and wrinkles occurred during transfer. Adhesion was insufficient in Comparative Examples 2 and 4.

Although the embodiment of the present invention has been described in detail with reference to the drawings, the specific configuration is not limited to this embodiment and includes design changes and the like within a range that does not deviate from the gist of the present invention.

1 ... Transfer laminate, 2 ... Transfer laminate, 11 ... Transfer layer, 12 ... Base layer, 13 ... Protective layer, 101 ... Fixed part, 102 ... Test part, 103 ... Puncture part

Claims

A transfer film having a thickness of 50 nm or more and 3000 nm or less.
A transfer film characterized in that the amount of indentation at break in the puncture test is 0.6 mm or more, and the load at the time of indentation of 0.4 mm in the puncture test is 20 mN or more and 250 mN or less.
The transfer film according to claim 1, wherein the load at break in the puncture test is 25 mN or more and 800 mN or less.
The transfer film according to claim 1 or 2, wherein a material having an ether bond or an ester bond in the main chain is used.
The transfer film according to any one of claims 1 to 3, wherein a material having a ring structure as a main chain is used.
The transfer film according to any one of claims 1 to 4, wherein a material having at least one of a hydroxy group, a carboxy group, an amide bond, and a urethane bond is used.
The transfer film according to any one of claims 1 to 5,
A base material layer laminated on at least one surface of the transfer film is provided.
The base material layer is a transfer laminate characterized in that a part or the whole is composed of any one of a liquid-absorbent film, a woven fabric, a knitted fabric, a non-woven fabric, and paper.
An arrangement step of arranging the transfer laminate according to claim 6 on the transfer target so that the transfer film side faces the transfer target.
A liquid absorbing step of causing the base material layer to absorb a liquid material, and
A method for transferring a transfer laminate, which comprises a transfer step of pressing the base material layer side of the transfer laminate to transfer the transfer film to the transfer subject.