CN209437726U - A kind of quaternized chitin lamination antiseptic dressing - Google Patents
A kind of quaternized chitin lamination antiseptic dressing Download PDFInfo
- Publication number
- CN209437726U CN209437726U CN201821663831.7U CN201821663831U CN209437726U CN 209437726 U CN209437726 U CN 209437726U CN 201821663831 U CN201821663831 U CN 201821663831U CN 209437726 U CN209437726 U CN 209437726U
- Authority
- CN
- China
- Prior art keywords
- lamination
- dressing
- layer
- sponge
- quaternized
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Abstract
The utility model relates to medical treatment and nursing instrument fields, and in particular to a kind of quaternized chitin lamination antiseptic dressing.The lamination antiseptic dressing is from top to bottom successively made of layers of nanofibers, sponge dressing layer and basal layer.The layers of nanofibers is made of electrospinning polycaprolactone fiber；The sponge dressing layer is made of quaternized chitin freeze-drying sponge；The basal layer is made of non-woven fabrics.Quaternized chitin lamination antiseptic dressing structure provided by the utility model is simple, and with excellent anti-microbial property and water suction performance of keeping humidity, has biggish application value in skin regeneration field.
Description
Technical field
The utility model relates to medical treatment and nursing instrument fields, and in particular to a kind of quaternized chitin lamination antiseptic dressing.
Background technique
Skin is the maximum histoorgan of human body, and how to improve post-traumatic remediation efficiency is always the hot spot being concerned
Problem.During clinical diagnosis and treatment, the use of wound dressing is very extensive, as hospital gauze can effective flap coverage, prevent
The generation of secondary injury and wound contamination.Bacterium infection is the most common complication of skin wound, frequently results in wound delay
It is not cured, or even endangers the life security of patient.To solve the above problems, research staff has developed miscellaneous antiseptic dressing
To prevent and treat bacterium infection.
Skin histology can generated a large amount of wound fluid by thermal damage such as burnt degree, easily the induction of the pollution surface of a wound
Bacteria breed.Clinician generallys use the modes such as gauze covering or negative pressure drainage and shifts wound fluid and then keep the surface of a wound
Relatively dry.With constantly bringing forth new ideas for life science in recent years, molecular mechanism and regulation of the research staff to regeneration
Strategy has further cognition.With traditional concept on the contrary, the local wound microenvironment that current research discovery moistens can promote epithelium
The proliferation and migration of cell, and then accelerate the agglutination of the surface of a wound.Therefore, traditional wound dressing including antiseptic dressing
Through the demand that cannot fully meet clinical application.Exploitation novel absorbent moisture retention wound dressing has become skin tissue engineering field
One of main flow direction.
In this context, it for the physics and chemistry and biology demand of wound reparation, provides and a kind of has both excellent anti-microbial property
There is biggish application value with the wound dressing of water suction performance of keeping humidity.
Summary of the invention
The purpose of the utility model is to overcome deficiencies in the prior art, provide a kind of quaternized chitin lamination antibacterial
Dressing, structure is simple, and with excellent anti-microbial property and water suction performance of keeping humidity, has biggish push away in skin regeneration field
Wide application value.
To achieve the above object, the utility model uses following technical scheme:
A kind of quaternized chitin lamination antiseptic dressing, which is characterized in that the lamination antiseptic dressing is from top to bottom successively
It is made of layers of nanofibers (1), sponge dressing layer (2) and basal layer (3)；The layers of nanofibers (1) is by electrospinning polycaprolactone
Fiber composition；The sponge dressing layer (2) is made of quaternized chitin freeze-drying sponge；The basal layer (3) is by non-woven fabrics group
At.
Preferably, the diameter of the electrospinning polycaprolactone fiber be 100-300 nm, the fibrous layer with a thickness of 0.1-
0.15 mm。
Preferably, the quaternized chitin freeze-drying sponge with a thickness of 1-3 mm, porosity 95-99%.
Preferably, the layers of nanofibers, sponge dressing layer are identical with basal layer shape, equal in magnitude, pass through sewer
Skill is combined with each other.
Preferably, the water absorption and swelling rate of the lamination antiseptic dressing is 760-1450%, moisture-vapor transmission 2200-
3000 g/m2·24h。
Preferably, the lamination antiseptic dressing is not less than 97% to the bacteriostasis rate of staphylococcus aureus and Escherichia coli.
Compared to the prior art, quaternized chitin compound antiseptic dressing described in the utility model uses above-mentioned technology
Method has reached following technical effect: electrospinning polycaprolactone fiber has good biocompatibility in layers of nanofibers (1),
And tissue is not glued, it can reduce pain of patient during dressing.Sponge is lyophilized in quaternized chitin in sponge dressing layer (2)
With excellent water imbibition, a large amount of wound fluid can be absorbed, maintains surface of a wound relative clean.Freeze-drying sponge sucks in water swelling after
Hydrogel can be formed and slowly evaporate moisture, the moist environment of the surface of a wound is maintained to promote histocyte regeneration.In addition, quaternized first
Shell element is a kind of biomaterial with broad spectrum antibacterial, can effectively inhibit bacteria breed, prevents and treats bacterial wound
Infection.The application of non-woven fabrics can further increase the mechanical property of lamination antiseptic dressing in basal layer (3).
Detailed description of the invention
Fig. 1 is the utility model overall structure diagram.
In attached drawing: 1- layers of nanofibers, 2- sponge dressing layer, 3- basal layer.
Specific embodiment
The utility model is understood and implemented for the ease of those of ordinary skill in the art, it is right with reference to the accompanying drawings and embodiments
The utility model is described in further detail, it should be appreciated that embodiment described herein is only used for describing and explaining this
Utility model is not used to limit the utility model.
As shown in Figure 1, Fig. 1 is the overall structure diagram of the quaternized chitin lamination antiseptic dressing of the utility model.Institute
Lamination antiseptic dressing is stated from top to bottom successively to be made of layers of nanofibers (1), sponge dressing layer (2) and basal layer (3)；It is described to receive
Rice fibrous layer (1) is made of electrospinning polycaprolactone fiber；Sponge group is lyophilized by quaternized chitin in the sponge dressing layer (2)
At；The basal layer (3) is made of non-woven fabrics.The diameter of the electrospinning polycaprolactone fiber is 100-300 nm；The fiber
Layer with a thickness of 0.1-0.15 mm；The quaternized chitin freeze-drying sponge with a thickness of 1-3 mm, porosity 95-99%；
The layers of nanofibers, sponge dressing layer are identical with basal layer shape, equal in magnitude, are combined with each other by sewing technology；Institute
The water absorption and swelling rate for stating lamination antiseptic dressing is 760-1450%, and moisture-vapor transmission is 2200-3000 g/m2·24h；It is described
Lamination antiseptic dressing is not less than 97% to the bacteriostasis rate of staphylococcus aureus and Escherichia coli.The main effect of the utility model
With antibacterial and maintenance surface of a wound moist environment is, to promote wound reparation.
As it will be easily appreciated by one skilled in the art that the above is only the preferred embodiment of the utility model only, not
To limit the utility model, any modification made within the spirit and principle of the present invention, equivalent replacement and change
Into etc., it should be included within the scope of protection of this utility model.
Claims (6)
1. a kind of quaternized chitin lamination antiseptic dressing, which is characterized in that the lamination antiseptic dressing from top to bottom successively by
Layers of nanofibers (1), sponge dressing layer (2) and basal layer (3) composition；The layers of nanofibers (1) is fine by electrospinning polycaprolactone
Dimension composition；The sponge dressing layer (2) is made of quaternized chitin freeze-drying sponge；The basal layer (3) is made of non-woven fabrics.
2. a kind of quaternized chitin lamination antiseptic dressing as described in claim 1, which is characterized in that the electrospinning is gathered in oneself
The diameter of ester fiber be 100-300 nm, the fibrous layer with a thickness of 0.1-0.15 mm.
3. a kind of quaternized chitin lamination antiseptic dressing as described in claim 1, which is characterized in that the quaternized crust
Element freeze-drying sponge with a thickness of 1-3 mm, porosity 95-99%.
4. a kind of quaternized chitin lamination antiseptic dressing as described in claim 1, which is characterized in that the nanofiber
Layer, sponge dressing layer are identical with basal layer shape, equal in magnitude, are combined with each other by sewing technology.
5. a kind of quaternized chitin lamination antiseptic dressing as described in claim 1, which is characterized in that the lamination antibacterial is applied
The water absorption and swelling rate of material is 760-1450%, and moisture-vapor transmission is 2200-3000 g/m2·24h。
6. a kind of quaternized chitin lamination antiseptic dressing as described in claim 1, which is characterized in that the lamination antibacterial is applied
Material is not less than 97% to the bacteriostasis rate of staphylococcus aureus and Escherichia coli.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821663831.7U CN209437726U (en) | 2018-10-15 | 2018-10-15 | A kind of quaternized chitin lamination antiseptic dressing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821663831.7U CN209437726U (en) | 2018-10-15 | 2018-10-15 | A kind of quaternized chitin lamination antiseptic dressing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209437726U true CN209437726U (en) | 2019-09-27 |
Family
ID=68009991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821663831.7U Expired - Fee Related CN209437726U (en) | 2018-10-15 | 2018-10-15 | A kind of quaternized chitin lamination antiseptic dressing |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209437726U (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111513395A (en) * | 2020-05-18 | 2020-08-11 | 武汉大学 | Novel antimicrobial environment-friendly mask and manufacturing method thereof |
| CN111529748A (en) * | 2020-04-16 | 2020-08-14 | 东华大学 | Medical composite dressing for wound repair and preparation method thereof |
| CN114618006A (en) * | 2022-04-11 | 2022-06-14 | 北京服装学院 | Intelligent wound dressing, preparation method and application thereof, and flexible sensor |
| CN114681663A (en) * | 2020-12-31 | 2022-07-01 | 广州迈普再生医学科技股份有限公司 | Multifunctional composite wound dressing and preparation method thereof |
| CN115634305A (en) * | 2022-12-16 | 2023-01-24 | 郑州大学第一附属医院 | Multifunctional electrostatic spinning composite nanofiber material and preparation method and application thereof |
-
2018
- 2018-10-15 CN CN201821663831.7U patent/CN209437726U/en not_active Expired - Fee Related
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111529748A (en) * | 2020-04-16 | 2020-08-14 | 东华大学 | Medical composite dressing for wound repair and preparation method thereof |
| CN111529748B (en) * | 2020-04-16 | 2021-06-04 | 东华大学 | Medical composite dressing for wound repair and preparation method thereof |
| CN111513395A (en) * | 2020-05-18 | 2020-08-11 | 武汉大学 | Novel antimicrobial environment-friendly mask and manufacturing method thereof |
| CN114681663A (en) * | 2020-12-31 | 2022-07-01 | 广州迈普再生医学科技股份有限公司 | Multifunctional composite wound dressing and preparation method thereof |
| CN114681663B (en) * | 2020-12-31 | 2023-05-05 | 广州迈普再生医学科技股份有限公司 | Multifunctional composite wound dressing and preparation method thereof |
| CN114618006A (en) * | 2022-04-11 | 2022-06-14 | 北京服装学院 | Intelligent wound dressing, preparation method and application thereof, and flexible sensor |
| CN114618006B (en) * | 2022-04-11 | 2022-11-25 | 北京服装学院 | Intelligent wound dressing, preparation method and application thereof, and flexible sensor |
| CN115634305A (en) * | 2022-12-16 | 2023-01-24 | 郑州大学第一附属医院 | Multifunctional electrostatic spinning composite nanofiber material and preparation method and application thereof |
| CN115634305B (en) * | 2022-12-16 | 2023-11-17 | 郑州大学第一附属医院 | Multifunctional electrostatic spinning composite nanofiber material and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN209437726U (en) | A kind of quaternized chitin lamination antiseptic dressing | |
| Xue et al. | Bioinspired multifunctional biomaterials with hierarchical microstructure for wound dressing | |
| Lin et al. | Evaluation of silver‐containing activated carbon fiber for wound healing study: in vitro and in vivo | |
| CN1833732A (en) | Making method of and use of antibiotic surgical dressing | |
| DE102007054127A1 (en) | A hygiene or personal care article comprising a proportion of hydroactive polymers and a preparation comprising bacteriophages or at least one component thereof | |
| CN102258801A (en) | Sponge calcium alginate medical dressing, and preparation method | |
| Ahmad et al. | Preparation and characterization of wool fiber reinforced nonwoven alginate hydrogel for wound dressing | |
| CN204655268U (en) | A kind of alginate medical dressing | |
| Liu et al. | Research progress on the use of micro/nano carbon materials for antibacterial dressings | |
| CN105597136A (en) | Moisture-transfer and fast drying wound dressing | |
| RU2578458C2 (en) | Multilayer wound dressing with multiple function nanomembranes and related products | |
| CN204655582U (en) | The dressing of a kind of hydrogel antibacterial gauze | |
| CN207575472U (en) | A kind of antibacterial anti hemorrhagic combine dressing | |
| WO2016029602A1 (en) | Total absorption dressing for viscous exudate and blood | |
| JP2007503275A (en) | New hygiene products | |
| WO2007134516A1 (en) | Medical dressing made from a silver-coated fabric | |
| CN207837915U (en) | A kind of low immune prototype wound dressing | |
| CN204158771U (en) | A kind of Bacterial cellulose/chitosan composite sponge dressing | |
| CN206508296U (en) | A kind of super water-absorbent foam dressing | |
| JP6059264B2 (en) | Biological fiber composite dressing material | |
| CN207605166U (en) | A kind of novel functional foam combine dressing | |
| WO2019056819A1 (en) | Collagen-loaded alginate medical dressing and preparation method therefor | |
| CN211095311U (en) | Traditional Chinese medicine bacteriostatic sanitary towel | |
| Sopata et al. | Modern methods of conservative treatment of pressure ulcers | |
| CN109498271B (en) | Directional liquid-absorbing anti-adhesion gauze and manufacturing method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20190927 Termination date: 20201015 |