CN112932750A - Magnetoelectric interbody fusion cage, interbody fusion cage post-operation position monitoring method and application - Google Patents
Magnetoelectric interbody fusion cage, interbody fusion cage post-operation position monitoring method and application Download PDFInfo
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- CN112932750A CN112932750A CN202110269208.3A CN202110269208A CN112932750A CN 112932750 A CN112932750 A CN 112932750A CN 202110269208 A CN202110269208 A CN 202110269208A CN 112932750 A CN112932750 A CN 112932750A
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Abstract
The invention relates to the technical field of medical treatment, and particularly discloses a magnetoelectric interbody fusion cage, a method for monitoring the position of an interbody fusion cage after operation and application, wherein the magnetoelectric interbody fusion cage is used for connecting two adjacent vertebrae, the magnetoelectric interbody fusion cage comprises an interbody fusion cage body and a signal receiver, and a magnetic object is arranged in the interbody fusion cage body; the signal receiver is arranged on the skin outside the vertebra; the signal receiver detects the induced current change generated when the interbody fusion cage body deforms and/or moves, so that the relative displacement of the magnetic object relative to the signal receiver can be monitored, the spine bending degree of a patient can be early warned by an electric signal, and the intervertebral disc can be prevented from shifting and falling off.
Description
Technical Field
The invention relates to the technical field of medical treatment, in particular to a magnetoelectric interbody fusion cage, a method for monitoring the position of an interbody fusion cage after operation and application.
Background
With the continuous development of medical technology, the fusion of lumbar interbody fusion cage is widely applied to medical operation as an orthopedic spinal fusion surgical operation. The interbody fusion cage can be implanted between two vertebral bodies, and can be fused with the upper vertebral body and the lower vertebral body simultaneously after nerve decompression, so that the compressed vertebral bodies and intervertebral discs can be fused into a whole without stimulating nerve tissues, and the treatment effect can be achieved.
At present, after a patient with various lumbar vertebra problems is subjected to an interbody fusion surgery, the interbody fusion cage (interbody fusion cage) may shift or even fall off due to postoperative movement of the patient, so that the patient suffers from clinical lumbocrural pain again, and in order to observe the state of the interbody fusion cage in the patient body and prevent intervertebral disc shifting and the falling off of the interbody fusion cage, a Computed Tomography (CT) technology is generally used for shooting and observation. However, the current CT technology used in clinic is expensive in use cost, complex in operation, long in detection time and waiting time, and cannot observe the position of the interbody fusion cage when the spine of a patient is bent in real time.
Therefore, the above technical solutions have the following disadvantages in practical use: CT examination is mostly adopted in methods for observing the postoperative position of the intervertebral fusion cage in the prior art, the problems of complex operation and high cost exist, and a novel non-CT technology needs to be developed to monitor the postoperative position of the intervertebral fusion cage and the bending degree of the spine of a patient in real time, so that the intervertebral disc displacement and the falling-off of the intervertebral fusion cage are prevented.
Disclosure of Invention
An object of an embodiment of the present invention is to provide a magnetoelectric intervertebral fusion device, so as to solve the problems that the existing methods for observing the postoperative position of the intervertebral fusion device proposed in the above background art mostly adopt CT examination, and have complex operation and high cost.
In order to achieve the above purpose, the embodiments of the present invention provide the following technical solutions:
a magnetoelectric intersomatic cage for connecting two adjacent vertebrae, comprising:
the interbody fusion cage comprises an interbody fusion cage body and a magnetic body, wherein the interbody fusion cage body is arranged between two adjacent vertebras;
the signal receiver is arranged on the skin (particularly back skin) outside the vertebra and used for monitoring the induced current change generated when the magnetic object is relatively displaced relative to the signal receiver when the interbody fusion cage body is deformed and/or moved, so that the bending degree of the vertebra of a patient can be early warned through an electric signal, and the intervertebral disc displacement and the dropping can be prevented.
As a further scheme of the invention: the magnetic object is a magnetic block, a nano magnetic fluid or a mixed block of magnetic powder and a polymer, wherein the polymer can be one or more of polydimethylsiloxane, polyurethane and rubber.
As a still further scheme of the invention: the magnetic object is made of materials including but not limited to one or more of neodymium iron boron magnet blocks and/or neodymium iron boron magnetic powder, neodymium nickel cobalt magnet blocks and/or neodymium nickel cobalt magnetic powder, iron oxide magnet blocks and/or iron oxide magnetic powder, chromium dioxide magnet blocks and/or chromium dioxide magnetic powder, cobalt-iron oxide magnet blocks and/or cobalt-iron oxide magnetic powder, metal magnet blocks and/or metal magnetic powder.
Another objective of an embodiment of the present invention is to provide a method for producing a magnetoelectric intervertebral cage, including the following steps: the magnetic object is fixed in the interbody fusion cage body (particularly the current commercial interbody fusion cage) to form the magnetoelectric interbody fusion cage, and the fixing method can be welding, additive manufacturing, glue bonding or connection of a physical mortise and tenon structure, and also can be one or a plurality of methods which are mixed for use.
Another object of the embodiments of the present invention is to provide a method for monitoring a post-operative position of an intervertebral fusion cage, wherein the method for monitoring the post-operative position of the intervertebral fusion cage adopts the above-mentioned magnetoelectric intervertebral fusion cage, specifically, two adjacent vertebrae are connected by the magnetoelectric intervertebral fusion cage, and the magnetoelectric intervertebral fusion cage includes an intervertebral fusion cage body and a magnetic object; meanwhile, a signal receiver is arranged on the skin outside the vertebra (particularly the back skin), and the change of induced current generated between the magnetic object and the signal receiver is monitored through the signal receiver so as to monitor the relative displacement and/or deformation of the magnetic object relative to the signal receiver in real time.
Another object of an embodiment of the present invention is to provide an application of the method for monitoring the post-operative position of the intervertebral fusion cage in real time determination of the position of the intervertebral fusion cage and the degree of curvature of the spine.
Compared with the prior art, the invention has the beneficial effects that:
1. the magnetoelectric interbody fusion cage provided by the invention can be used for connecting two adjacent vertebrae, and comprises an interbody fusion cage main body and a signal receiver, wherein a magnetic object is arranged in the interbody fusion cage main body, the signal receiver is arranged on the skin at the outer side of the vertebrae, and the signal receiver detects the induced current change generated when the interbody fusion cage main body deforms and/or moves, so that the relative displacement of the interbody fusion cage is monitored in real time by the non-CT technology for the first time. The method is light, simple and low in cost, facilitates the monitoring of the postoperative spinal curvature degree of a patient by a doctor after operation and the judgment of whether the intervertebral fusion cage implanted into the patient falls off, and is a method for early warning the spinal curvature degree of the patient through electric signals so as to prevent the intervertebral disc from shifting and falling off.
2. The invention realizes the aim of monitoring the position of the interbody fusion cage in real time by utilizing an electromagnetic induction mechanism, and is beneficial to further development towards the directions of convenience, intellectualization and the like.
3. The production method of the magnetoelectric interbody fusion cage provided by the invention has the advantages of simple equipment, easiness in operation, low energy consumption in the production process and low cost, and is suitable for industrial large-scale production; the anti-drop interbody fusion cage manufactured by the method is easy to install by doctors in operation, meets the requirement of practical use, and has great application value.
Drawings
Fig. 1 is a schematic view illustrating an installation position of a magnetoelectric intervertebral cage and a signal receiver according to an embodiment of the present invention.
Fig. 2 is a schematic structural diagram of a magnetoelectric intervertebral cage according to an embodiment of the present invention.
Fig. 3 is a schematic structural diagram of a magnetoelectric intervertebral cage according to an embodiment of the present invention in a normal state.
Fig. 4 is a schematic structural diagram of a magnetoelectric intervertebral cage according to an embodiment of the present invention in a disengaged state.
Fig. 5 is a schematic structural diagram of a magnetoelectric intervertebral cage according to an embodiment of the present invention in different states when monitoring the degree of curvature of the spine.
In the figure: 1-the vertebra; 2-magnetoelectric interbody fusion cage; 3-skin; 4-a signal receiver; 5-interbody cage body; 6-magnetic object.
Detailed Description
In order to make the technical problems, technical solutions and advantages of the present invention more apparent, the present invention will be further described in detail with reference to the accompanying drawings and specific embodiments. The following examples will assist those skilled in the art in further understanding the invention, but are not intended to limit the invention in any way. It should be noted that variations and modifications can be made by persons skilled in the art without departing from the spirit of the invention. All falling within the scope of the present invention. In order to make the technical solution of the present invention clearer, process steps and device structures well known in the art are omitted here.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
In order to achieve the above purpose, the embodiments of the present invention provide the following technical solutions:
as shown in fig. 1-2, a magnetoelectric intersomatic cage 2, the magnetoelectric intersomatic cage 2 for connecting two adjacent vertebrae 1, the magnetoelectric intersomatic cage 2 includes:
an interbody cage body 5 disposed between two adjacent vertebrae 1, the interbody cage body 5 having a magnetic body 6 disposed therein;
the signal receiver 4 is arranged on the skin 3 (particularly back skin) outside the vertebra 1 and used for monitoring the induced current change generated when the magnetic object 6 is relatively displaced relative to the signal receiver 4 when the interbody fusion cage body 5 is deformed and/or moved, so that the spine bending degree of a patient can be early warned through an electric signal, and the intervertebral disc displacement and the intervertebral disc falling can be prevented.
In the embodiment of the invention, as the magnetic object 6 is arranged in the interbody fusion cage body 5 (specifically, a commercial interbody fusion cage at present), and the signal receiver 4 is arranged (specifically, a coil receiver is arranged on the posterior skin of the vertebra), the signal receiver 4 monitors the induced current change generated when the magnetic object 6 is relatively displaced relative to the signal receiver 4 in real time, so as to monitor the postoperative position of the interbody fusion cage and the degree of curvature of the vertebra after the operation of a patient in real time, thereby preventing the displacement of the intervertebral disc and the falling-off of the interbody fusion cage. When the intervertebral fusion cage slides relatively to the upper and lower vertebral bodies and even falls off, the relative displacement of the magnetic object 6 inside the intervertebral fusion cage relative to the coil receiver outside the skin changes, so that the magnetic flux passing through the coil receiver changes, and the induced current is monitored. Meanwhile, the magnetoelectric interbody fusion cage can also monitor the state of the spine in the movement process of the postoperative patient. When the human spine of the interbody fusion cage is bent, the relative displacement of the magnetic object 6 (permanent magnetic substance) inside the interbody fusion cage relative to the coil receiver outside the skin is changed, so that the magnetic flux passing through the coil receiver is changed, and the induced current is monitored.
As another preferred embodiment of the present invention, the magnetic object 6 is a magnetic block, a nano-magnetic fluid, or a mixed block of magnetic powder and polymer, wherein the polymer may be one or more of polydimethylsiloxane, polyurethane, and rubber.
As another preferred embodiment of the present invention, the material of the magnetic block and the material of the magnetic powder are each independently one or more selected from the group consisting of a neodymium-iron-boron magnetic material, a neodymium-nickel-cobalt magnetic material, a ferromagnetic oxide material, a chromium dioxide magnetic material, a cobalt-ferromagnetic oxide material, and the like. The magnetic material 6 includes, but is not limited to, one or more of neodymium iron boron magnet and/or neodymium iron boron magnetic powder, neodymium nickel cobalt magnet and/or neodymium nickel cobalt magnetic powder, iron oxide magnet and/or iron oxide powder, chromium dioxide magnet and/or chromium dioxide magnetic powder, cobalt-iron oxide magnet and/or cobalt-iron oxide powder, metal magnet and/or metal magnetic powder.
As another preferred embodiment of the present invention, the magnetic substance 6 is disposed in the intervertebral cage body 5 at a mass percentage of 10% to 70%.
In another preferred embodiment of the present invention, when the magnetic body 6 is a mixed bulk of a magnetic powder and a polymer, the particle size of the magnetic powder is 0.01 to 500 μm.
As another preferred embodiment of the present invention, further, the magnetic body 6 is fixed inside the main body 5 of the intervertebral fusion device by welding, additive manufacturing, glue bonding or physical mortise and tenon structure connection, or by using one or more of these methods in combination, as long as the fixed connection can be achieved, which is not limited herein.
As another preferred embodiment of the present invention, a polymer protective paint is disposed on the exterior of the interbody fusion cage body 5, and the material of the polymer protective paint includes, but is not limited to, one or more of polyester, polyolefin, polyamide, and graft copolymer.
As another preferred embodiment of the invention, the polymer protective paint is arranged outside the interbody fusion cage body 5 by electroplating, physical deposition or painting, and the reaction between biological tissues and the interbody fusion cage is blocked by introducing the outer polymer protective paint as a protective layer.
As another preferred embodiment of the present invention, the signal receiver 4 (coil receiver) is a conductive coil, which may be one or more of a copper coil, a silver coil, a gold coil, a liquid metal coil, or a coil made by printing conductive polymer and/or metal nanoparticles on a fabric.
As another preferred embodiment of the invention, the diameter of the conductive coil is between 1 cm and 10 cm, and the number of coil turns is 1 to 500 turns.
Another objective of an embodiment of the present invention is to provide a method for producing a magnetoelectric intervertebral cage, including the following steps:
a1, fixing the magnetic object 6 in the interbody fusion cage body 5 (particularly the current commercial interbody fusion cage) to form the magnetoelectric interbody fusion cage 2, wherein the fixing method can be welding, additive manufacturing, glue bonding or physical mortise and tenon structure connection, or can be one or a mixture of the methods.
A2, introducing an outer protective layer on the outer part of the interbody fusion cage body 5 by electroplating, physical deposition or painting a polymer protective paint, and blocking the reaction between biological tissues and the interbody fusion cage.
A3, the magnetic object 6 can be a magnetic block, a nano magnetic fluid or a mixed block of magnetic powder/polymer, wherein the polymer can be one or more of polydimethylsiloxane, polyurethane and rubber.
As another preferred embodiment of the present invention, the fixing method for fixing the magnetic object 6 in the main body 5 of the interbody fusion cage and the method for protecting the magnetic object by electroplating, physical deposition or painting a polymer protective paint can be implemented by the prior art, and the specific process conditions can be selected according to the needs, which are not described herein again.
The embodiment of the invention also provides the magnetoelectric interbody fusion cage prepared by the production method of the magnetoelectric interbody fusion cage.
The embodiment of the invention also provides a method for monitoring the post-operation position of the interbody fusion cage, which adopts the magnetoelectric interbody fusion cage, and particularly connects two adjacent vertebra 1 through the magnetoelectric interbody fusion cage 2, wherein the magnetoelectric interbody fusion cage 2 comprises an interbody fusion cage main body 5 and a magnetic object 6; meanwhile, a signal receiver 4 is arranged on the skin 3 (particularly back skin) outside the vertebra 1, and the induced current change generated between the magnetic object 6 and the signal receiver 4 is monitored through the signal receiver 4 so as to monitor the relative displacement and/or deformation of the magnetic object 6 relative to the signal receiver 4 in real time.
The embodiment of the invention also provides application of the method for monitoring the postoperative position of the interbody fusion cage in real-time judgment of the position of the interbody fusion cage and the degree of curvature of the spine.
The technical effects of the magnetoelectric intervertebral cage of the present invention will be further described below by referring to specific embodiments.
Example 1
A method for monitoring the postoperative position of an intervertebral fusion cage specifically comprises the following steps:
the magnetic neodymium iron boron block is fixed in the current commercial interbody fusion cage by an additive manufacturing technology, the exterior of the magnetic neodymium iron boron block is wrapped by medical polyether ether ketone (PEEK) polymer, and the reaction between biological tissues and the interbody fusion cage is blocked, so that the magnetoelectric interbody fusion cage 2 is formed.
A1 cm diameter, 20 turn copper coil receiver was placed on the skin opposite the vertebrae.
After the fusion of the lumbar interbody fusion cage, the patient leans forward, the relative displacement of the inner permanent magnetic substance (magnetic neodymium iron boron block) relative to the coil outside the skin changes, so that the magnetic flux of the coil changes, and the induced voltage of 25 microvolts is monitored by the copper coil receiver. The patient leans back and an induced voltage of 76 microvolts is generated which is monitored by a copper coil receiver. If the magnetoelectric intervertebral fusion device 2 falls off, the induced voltage of 1200-1500 microvolts is monitored by the copper coil receiver.
Example 2
A method for monitoring the postoperative position of an intervertebral fusion cage specifically comprises the following steps:
the magnetic neodymium-nickel-cobalt powder with the mass percentage of 42 percent and the particle size of 120 mu m is fixed in the current commercial interbody fusion cage by the glue bonding technology, the outside of the magnetic neodymium-nickel-cobalt powder is wrapped by medical polyimide polymer, and the reaction between biological tissues and the interbody fusion cage is blocked, so that the magnetoelectric interbody fusion cage 2 is formed.
A conductive silver coil receiver of 200 turns, 1 cm in diameter, was placed on the skin opposite the vertebrae.
After the fusion of the lumbar interbody fusion cage, the patient leans forwards, the relative displacement of the inner permanent magnetic substance (magnetic neodymium iron boron block) relative to the coil outside the skin is changed, and thus, the magnetic flux of the coil is changed, and the induction voltage of 21 microvolts is monitored by the conductive silver coil receiver. The patient leans back and an induced voltage of 88 microvolts is monitored by a conductive silver coil receiver. If the magnetoelectric intervertebral fusion device 2 falls off, the induced voltage of 700-900 microvolts is monitored by the conductive silver coil receiver.
Example 3
A method for monitoring the postoperative position of an intervertebral fusion cage specifically comprises the following steps:
the magnetic fluid of the nano magnetic ferrite with the mass percent of 72 percent is fixed in the current commercial interbody fusion cage by a physical wrapping technology, the outside of the magnetic fluid is wrapped by medical polyurethane polymer, and the reaction between biological tissues and the interbody fusion cage is blocked to form the magnetoelectric interbody fusion cage 2.
A 300-turn coil receiver of conductive polyaniline having a diameter of 5 cm was placed on the skin opposite the vertebrae.
After the fusion of the lumbar interbody fusion cage, the patient leans forward, the relative displacement of the inner permanent magnetic substance (magnetic neodymium iron boron block) relative to the coil outside the skin changes, so that the magnetic flux of the coil changes, and the induced voltage of 50 microvolts is monitored by the conductive polyaniline coil receiver. The patient leans back and an induced voltage of 123 microvolts is generated which is monitored by a conductive polyaniline coil receiver. If the magnetoelectric intervertebral fusion cage 2 falls off, the induced voltage of 1700-2000 microvolts is monitored by the conductive polyaniline coil receiver.
Example 4
As shown in fig. 1-2, a magnetoelectric intersomatic cage 2 includes an intersomatic cage body 5, the intersomatic cage body 5 being disposed between two adjacent vertebrae 1, a magnetic body 6 being disposed within the intersomatic cage body 5;
the magnetoelectric interbody fusion cage 2 is used for connecting two adjacent vertebra 1, and the magnetoelectric interbody fusion cage 2;
the signal receiver 4 is arranged on the outer side of the skin 3 (particularly back skin) on the outer side of the vertebra 1 and is used for being matched with the magnetic object 6 to generate induced current, when the interbody fusion cage body 5 deforms and/or moves, the induced current change generated when the magnetic object 6 relatively displaces relative to the signal receiver 4 is monitored, and therefore the spine bending degree of a patient can be early warned through electric signals, and the intervertebral disc displacement and the intervertebral disc falling can be prevented.
Example 5
The magnetoelectric interbody fusion cage 2 of embodiment 4 is used in the lumbar interbody fusion, specifically referring to fig. 1, which is a schematic diagram of the installation positions of the magnetoelectric interbody fusion cage 2 and the signal receiver 4, and after the operation, the magnetoelectric interbody fusion cage 2 is used to monitor whether the intervertebral disc is dislocated, and it should be noted that, in order to observe the state of the interbody fusion cage after the operation of the lumbar interbody fusion cage in the body of the patient, the current prior art generally uses the CT technology to shoot and observe. However, CT techniques are expensive, time consuming and require long waiting times. Therefore, there is a need to develop new non-CT techniques for real-time monitoring of the position of the interbody cage. At present, the method of installing the sensor in vitro (for example, the technical schemes disclosed in chinese patent nos. 2018218375284, 2012204108882, and 2017105307925) is adopted to monitor the physical form of the vertebra, but because the sensor is attached to the external skin by such a method, the situation that the intervertebral disc in the body bends along with the spine of the human body cannot be accurately reflected, and the falling situation of the intervertebral disc in the body cannot be accurately monitored. Currently, there is no report of monitoring the position of an interbody cage using electromagnetic induction effect.
After the magnetoelectric interbody fusion cage 2 is used in the lumbar interbody fusion surgery, the schematic diagram of the magnetoelectric interbody fusion cage 2 in the normal state is shown in fig. 3, and the schematic diagram of the magnetoelectric interbody fusion cage 2 in the falling state is shown in fig. 4. When the intervertebral fusion cage relatively slides or even falls off relative to the upper and lower vertebral bodies, the relative displacement of the permanent magnetic substance inside the intervertebral fusion cage relative to the coil outside the skin changes, and further when the intervertebral fusion cage relatively slides or even falls off, the magnetic flux of the coil changes, and the generated induced current is monitored.
Example 6
The magnetoelectric intersomatic cage 2 of example 4 was used in the lumbar interbody cage fusion, and after the operation, the degree of curvature of the spine was monitored by the magnetoelectric intersomatic cage 2, as shown in fig. 5, the magnetic intersomatic cage in the human vertebral body supine state (a view), normal state (b view) and anteverted state (c view) was changed. When the intervertebral fusion cage deforms along with the bending of the human vertebra, the relative displacement of the permanent magnetic substance inside the intervertebral fusion cage relative to the coil outside the skin changes, so that the magnetic flux of the coil changes, induced current is generated and monitored, and the state of the vertebra of a postoperative patient in the movement process is monitored.
Example 7
The same as example 1 except that the magnetic ndfeb block was replaced with a neodymium nickel cobalt magnetic block, compared to example 1.
Example 8
The same as example 1 except that the magnetic neodymium iron boron block is replaced by the iron oxide magnetic block as compared with example 1.
Example 9
Compared with the embodiment 1, the method is the same as the embodiment 1 except that the magnetic neodymium iron boron block body is replaced by the chromium dioxide magnetic block.
Example 10
The same as example 1 except that the magnetic ndfeb blocks were replaced with cobalt-iron oxide magnetic blocks, compared to example 1.
Example 11
Compared with the embodiment 2, the method is the same as the embodiment 2 except that the NdFeB magnetic powder with the mass percentage of 10% and the grain diameter of 0.01 mu m is fixed inside and outside the current commercial intervertebral fusion device by the glue bonding technology.
Example 12
Compared with the embodiment 2, the method is the same as the embodiment 2 except that 70 mass percent of neodymium iron boron magnetic powder with the particle size of 500 mu m is fixed inside and outside the current commercial intervertebral fusion device by the glue bonding technology.
Example 13
Compared with the embodiment 2, the method is the same as the embodiment 2 except that the cobalt-iron oxide magnetic powder with the mass percentage of 20 percent and the grain diameter of 1 mu m is fixed inside and outside the current commercial intervertebral fusion device by the glue bonding technology.
Example 14
Compared with the embodiment 2, the method is the same as the embodiment 2 except that the chromium dioxide magnetic powder with the mass percentage of 50 percent and the grain diameter of 10 mu m is fixed inside and outside the current commercial intervertebral fusion device by the glue bonding technology.
Example 15
Compared with the embodiment 2, the method is the same as the embodiment 2 except that the metal magnetic powder with the mass percentage of 60 percent and the grain diameter of 100 mu m is fixed inside and outside the current commercial intervertebral fusion device by the glue bonding technology.
Example 16
The same as example 1, except that a2 cm diameter, 1 turn copper coil receptor was placed on the skin opposite the vertebrae as compared to example 1.
Example 17
The same as example 1, except that a 7 cm diameter, 10 turn copper coil receptor was placed on the skin opposite the vertebrae as compared to example 1.
Example 18
The same as example 1, except that a 500-turn copper coil receptor of 10 cm diameter was placed on the skin opposite the vertebrae, as compared to example 1.
The magnetoelectric interbody fusion cage provided by the invention is used for connecting two adjacent vertebra 1, and the magnetoelectric interbody fusion cage 2 comprises: an interbody fusion cage body 5 and a signal receiver 4, wherein a magnetic object 6 is arranged in the interbody fusion cage body 5; signal receiver 4 sets up on the skin 3 (specifically back skin) in vertebra 1 outside, detects through signal receiver 4 the induced-current that produces when deformation and/or removal takes place for interbody fusion cage main part 5 changes, and then can realize the control magnetic object 6 for the relative displacement that signal receiver 4 took place to can realize passing through the signal of telecommunication to its vertebra bending degree of patient's early warning, and prevent that the intervertebral disc shifts and drops, light, simple, the expense is lower, has solved current method that is used for observing interbody fusion cage postoperative position and has adopted CT inspection mostly, has the operation complicacy, the expensive problem of expense, has wide market prospect. The invention provides a method for monitoring the position of an intervertebral fusion cage after operation, in particular to a method for monitoring and preventing the intervertebral fusion cage from falling off after operation by using a magnetic intervertebral fusion cage/a coil receiver placed on the skin. When the intervertebral fusion cage bends along with the human vertebra, the relative displacement of the magnetic substance inside the intervertebral fusion cage relative to the coil outside the skin changes, so that the magnetic flux passing through the coil changes, and the induced current is monitored. Its advantages are as follows: the relative displacement of the interbody fusion cage is monitored in real time by the non-CT technology for the first time. The method is light, simple and low in cost, is convenient for doctors to monitor the bending degree of the spine of a patient after operation and monitor whether the intervertebral fusion cage implanted into the body of the patient falls off, and is a method for preventing the intervertebral disc from shifting and falling off by early warning the bending degree of the spine of the patient through electric signals.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art through specific situations.
The standard parts used by the invention can be purchased from the market, the special-shaped parts can be customized according to the description and the description of the attached drawings, and the specific connection mode of each part can adopt the conventional means of mature bolts, rivets, welding and the like in the prior art, and the detailed description is not repeated.
The above detailed description of the preferred embodiments of the present invention, but the above embodiments are only used to illustrate the technical solutions of the present invention, and not to limit the same; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions deviate from the technical solutions of the embodiments of the present invention. And obvious variations or modifications of the invention may be made without departing from the scope of the invention.
Claims (10)
1. A magnetoelectric intersomatic cage for connecting two adjacent vertebrae, comprising:
the interbody fusion cage comprises an interbody fusion cage body and a magnetic body, wherein the interbody fusion cage body is arranged between two adjacent vertebras; and
and the signal receiver is arranged on the skin outside the vertebra and used for monitoring the variation of induced current generated when the magnetic object is relatively displaced relative to the signal receiver when the interbody fusion cage body is deformed and/or moved.
2. The magnetoelectric intersomatic cage according to claim 1, wherein the magnetic object is a magnetic block, a nano magnetic fluid or a mixed block of magnetic powder and a polymer, wherein the polymer is one or more of polydimethylsiloxane, polyurethane and rubber.
3. The magnetoelectric intersomatic cage of claim 2, wherein the magnetic block and the magnetic powder are each independently selected from one or more of neodymium iron boron magnetic material, neodymium nickel cobalt magnetic material, iron oxide magnetic material, chromium dioxide magnetic material, and cobalt-iron oxide magnetic material.
4. The magnetoelectric intersomatic cage according to claim 2, wherein the magnetic powder has a particle size of 0.01 to 500 μm when the magnetic substance is a mixed bulk of magnetic powder and polymer.
5. The magnetoelectric intersomatic cage according to claim 1, wherein the magnetic object is provided in the intersomatic cage body in an amount of 10 to 70% by mass.
6. The magnetoelectric intersomatic cage according to claim 1, wherein a polymer protective paint is provided on the exterior of the intersomatic cage body, and the polymer protective paint is one or more of polyester, polyolefin, polyamide and graft copolymer.
7. The magnetoelectric intersomatic cage according to claim 1, wherein the signal receiver is an electrically conductive coil, in particular one or more of a copper coil, a silver coil, a gold coil, a liquid metal coil.
8. The magnetoelectric intersomatic cage of claim 7, wherein the electrically conductive coil has a diameter of between 1 cm and 10 cm and a number of coil turns of between 1 and 500 turns.
9. A method of monitoring a post-operative position of an intersomatic cage using a magnetoelectric intersomatic cage according to any one of claims 1 to 8, wherein the method of monitoring a post-operative position of an intersomatic cage comprises the steps of:
connecting two adjacent vertebrae through a magnetoelectric interbody fusion cage, wherein the magnetoelectric interbody fusion cage comprises an interbody fusion cage body and a magnetic object; meanwhile, a signal receiver is arranged on the skin outside the vertebra, and the signal receiver is used for monitoring the variation of induced current generated between the magnetic object and the signal receiver so as to monitor the relative displacement and/or deformation of the magnetic object relative to the signal receiver in real time.
10. Use of a method of monitoring the post-operative position of an intersomatic cage according to claim 9 for determining the position of the intersomatic cage and/or the degree of curvature of the spine in real time.
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