CN111035793B - Developing suture capable of monitoring displacement and preparation method thereof - Google Patents
Developing suture capable of monitoring displacement and preparation method thereof Download PDFInfo
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- CN111035793B CN111035793B CN201911249422.1A CN201911249422A CN111035793B CN 111035793 B CN111035793 B CN 111035793B CN 201911249422 A CN201911249422 A CN 201911249422A CN 111035793 B CN111035793 B CN 111035793B
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- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
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Abstract
The invention relates to a developing suture capable of monitoring displacement and a preparation method thereof, wherein the preparation method comprises the following steps: carrying out partial development treatment on the core wire to obtain a development suture line capable of monitoring displacement, wherein the partial development treatment is to divide a linear region on the surface of the core wire into a plurality of sub-regions along the length direction, and control one of every two adjacent sub-regions to be developable under X-rays and the other to be undevelopable under the X-rays; the obtained development suture capable of monitoring displacement comprises a core wire, wherein a linear region on the surface of the core wire is divided into a plurality of sub-regions along the length direction, and one of the adjacent two sub-regions can be developed under X-rays, and the other one can not be developed under the X-rays. The preparation method of the developing suture capable of monitoring displacement is simple, convenient and strong in operability; the developing suture capable of monitoring displacement, which is prepared by the method, skillfully realizes the monitoring of whether the suture slips or the trend of slippage, and has practical significance and popularization value.
Description
Technical Field
The invention belongs to the technical field of medical materials, and relates to a developing suture capable of monitoring displacement and a preparation method thereof.
Background
In order to prevent the used gauze from remaining in the body of a patient during the operation, the used operation gauze is provided with a developing line which is not penetrated by X-rays and can be clearly displayed on an X-ray machine display screen or a photograph.
The existing developing technology mainly comprises the steps of mixing a developer and yarn raw materials to prepare developed yarns or directly coating the developer on the surface of a developing line to enable the yarns to have the developing function. Patent CN 1776034A discloses a medical X-ray developing fiber and a manufacturing method thereof, wherein a developing agent and a fiber raw material are mixed and stirred, and are extruded and spun by a screw extruder to prepare the developing fiber; the patent CN 105903061A discloses a production process of a self-adhesive X-ray medical developing line and medical gauze, wherein the X-ray medical developing line is formed by mixing and spinning developing raw materials to prepare X-ray developing fibers, and then self-adhering the fibers on the medical gauze in an ironing mode; patent CN 106827379a discloses a production process of a sandwich development line, wherein the sandwich development line comprises a core wire and an outer layer material, the core wire is put in after the outer layer material is melted, the core wire is coated by the outer layer material to form the sandwich development line; patent CN 106725677a discloses a long-time-placed absorbable suture line for X-ray development, wherein the long-time-placed absorbable suture line for X-ray development is prepared by coating a core wire with a developer and then weaving an outer sleeve to make the suture line.
The use scene of the developing suture requires regular observation of whether the suture has the possibility of slipping, however, the developing suture in the prior art does not have the capability of displaying displacement and cannot intuitively indicate whether the yarn has slipping.
Therefore, the research on the developing suture line with the displacement display function and the preparation method thereof have very important significance.
Disclosure of Invention
The invention aims to solve the problem that the developing suture line does not have the displacement display function in the prior art, and aims to solve the problem that the developing suture line in the prior art is poor in mechanical property or not durable in developing effect, and provides the developing suture line capable of monitoring the displacement and the preparation method thereof.
In order to achieve the purpose, the invention adopts the following scheme:
a method for preparing developing suture capable of monitoring displacement comprises the steps of carrying out partial developing treatment on a core wire to obtain the developing suture capable of monitoring displacement, wherein the partial developing treatment is to divide a linear region on the surface of the core wire into a plurality of sub-regions along the length direction (namely the sub-regions are sequentially arranged along the length direction of the core wire, the linear region on the surface of the core wire can be an integral region on the surface of the core wire or a partial region on the surface of the core wire), and controlling one of two adjacent sub-regions to be developable under X-rays and the other to be undevelopable under the X-rays;
according to the invention, the linear area on the surface of the core wire is divided into a plurality of subareas which are alternately arranged under the X-ray development and the X-ray undevelopable, and under the X-ray, whether the suture line slips or the trend of slippage occurs can be judged according to the number of the developable subareas and the undevelopable subareas, so that doctors and patients can be helped to find the displacement condition of the suture line in advance through the development when no sign occurs, and a corresponding treatment scheme can be made in advance.
As a preferred technical scheme:
according to the preparation method of the developing suture capable of monitoring displacement, after partial developing treatment, the sleeve is also woven on the surface of the core wire, the sleeve can increase the stability of the diameter of the suture wire, the surface performance and the holding performance of the suture wire are improved, the core wire developer can be protected in a certain sense, the developer loss and deformation caused by friction are reduced, the material of the sleeve is the same as that of the core wire, and theoretically, the material of the sleeve and the material of the core wire do not have specific requirements.
In the above method for preparing the developing suture line capable of monitoring displacement, the core wire is made of ultra-high molecular weight polyethylene, nylon, polyester or polypropylene.
The method for preparing the developing suture line capable of monitoring displacement comprises the following specific processes of: after the surface of the core wire is sprayed with the developer or the mixture of the developer and the medical glue at certain intervals (preferably, the developer and the medical glue are sprayed at equal intervals), the developer or the mixture of the developer and the medical glue is dried and hardened, the general developer such as barium sulfate and the like has no adhesiveness, the developer is simply coated on the surface of the suture line during implantation and is repeatedly washed by tissue fluid and the like to cause the rapid loss and the failure of the developer, and the medical glue can increase the fixing performance of the developer and still maintain the specific development characteristic in long-term implantation.
In the above method for preparing a development suture capable of monitoring displacement, the specific process of the partial development treatment may also be: the single-strand wrapping wire which can be developed under X-ray is spirally wound and fixed on the core wire, and the displacement condition of the suture can be judged according to the number of turns of spiral winding.
In the above method for preparing a development suture capable of monitoring displacement, the specific process of the partial development treatment may be as follows: fix the two-strand fasciated line spiral winding that can develop under X-ray on the core line, the winding starting point of two-strand fasciated line is the same, and the winding direction is clockwise and anticlockwise respectively, and winding pitch is the same, wholly is the scissor-fork structure, and perhaps the winding starting point of two-strand fasciated line is different, and the winding direction is the same, and winding pitch is the same, and two strands of fasciated line crisscross winding, similar two interval 180 sinusoidal curve main part are axisymmetric along the core line.
According to the preparation method of the developing suture capable of monitoring the displacement, the medical adhesive is adopted for fixation, and the fixation mode can ensure that the developer can be firmly attached to the surface of the suture without changing the original mechanical property of the suture.
The preparation method of the developing suture capable of monitoring the displacement comprises the steps that the wrapping wire consists of a wrapping wire body and a developer or a mixture of the developer and medical glue coated on the wrapping wire body; or, the wrapped wire is composed of a wrapped wire body and a developer dispersed in the wrapped wire body; or the wrapping wire is a metal nickel titanium wire without memory characteristics.
According to the preparation method of the developing suture capable of monitoring the displacement, the material of the wrapping wire is the same as that of the core wire.
The invention also provides a displacement-monitorable development suture prepared by the displacement-monitorable development suture preparation method, which comprises a core wire, wherein a linear region on the surface of the core wire is divided into a plurality of subareas along the length direction, one of every two adjacent subareas can be developed under X-rays, and the other subarea can not be developed under the X-rays.
Has the advantages that:
(1) the preparation method of the developing suture capable of monitoring displacement is simple, convenient and strong in operability;
(2) the displacement-monitorable development suture prepared by the preparation method of the displacement-monitorable development suture skillfully realizes the monitoring of whether the suture slips or the trend of slippage occurs, and has practical significance and popularization value.
Drawings
FIG. 1 is a schematic view of a core wire subjected to a partial development treatment in embodiment 1 of the present invention;
FIG. 2 is a schematic view of a core wire subjected to a partial development treatment in embodiment 6 of the present invention;
FIG. 3 is a schematic view of a core wire subjected to a partial development treatment in embodiment 10 of the present invention;
FIG. 4 is a schematic view showing a core wire subjected to a partial development treatment in example 14 of the present invention;
1-undevelopable sub-region, 2-developable sub-region, 3-linear region.
Detailed Description
The invention will be further illustrated with reference to specific embodiments. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention. Further, it should be understood that various changes or modifications of the present invention may be made by those skilled in the art after reading the teaching of the present invention, and such equivalents may fall within the scope of the present invention as defined in the appended claims.
Example 1
A method for preparing a developing suture capable of monitoring displacement comprises the following steps of carrying out partial developing treatment on an ultrahigh molecular weight polyethylene core wire to obtain the developing suture capable of monitoring displacement, wherein as shown in figure 1, the partial developing treatment divides a linear region 3 on the surface of the ultrahigh molecular weight polyethylene core wire into 9 sub-regions along the length direction, one of two adjacent sub-regions is controlled to be developable under X-rays, namely a sub-region 2 which can be developed, and the other is controlled to be undevelopable under the X-rays, namely a sub-region 1 which cannot be developed, and the specific process of the partial developing treatment is as follows: and spraying a developer on the surface of the ultrahigh molecular weight polyethylene core wire at a certain interval, and drying and hardening.
Example 2
A method for preparing a developing suture capable of monitoring displacement, which is basically the same as that in the embodiment 1, and is characterized in that the material of a core wire, namely ultrahigh molecular weight polyethylene, is replaced by nylon, and a developer is replaced by a mixture of the developer and medical adhesive; the displacement-monitorable development stitch structure obtained by this method is the same as in example 1.
Example 3
A method for preparing a displacement-monitorable development suture, which is substantially the same as that in example 1, except that the material of the core wire, namely the ultra-high molecular weight polyethylene, is replaced by polyester; the displacement-monitorable development stitch structure obtained by this method is the same as in example 1.
Example 4
A method for preparing a developing suture capable of monitoring displacement, which is basically the same as that in the embodiment 1, and is characterized in that the material of a core wire, namely ultrahigh molecular weight polyethylene, is replaced by polypropylene, and a developer is replaced by a mixture of the developer and medical adhesive; the displacement-monitorable development stitch structure obtained by this method is the same as in example 1.
Example 5
A method for preparing a developing suture capable of monitoring displacement is basically the same as that in the embodiment 1, except that after partial developing treatment, a sleeve with the same material as that of an ultrahigh molecular weight polyethylene core wire is woven on the surface of the ultrahigh molecular weight polyethylene core wire; the displacement-monitorable development stitch structure obtained by this method is the same as in example 1.
Example 6
A method for preparing a developing suture capable of monitoring displacement comprises the following steps of carrying out partial developing treatment on an ultrahigh molecular weight polyethylene core wire to obtain the developing suture capable of monitoring displacement, wherein as shown in figure 2, the partial developing treatment divides a linear region 3 on the surface of the ultrahigh molecular weight polyethylene core wire into 7 sub-regions along the length direction, one of two adjacent sub-regions is controlled to be developable under X-rays, namely, a sub-region 2 which can be developed, and the other is controlled to be undevelopable under the X-rays, namely, a sub-region 1 which cannot be developed, and the specific process of the partial developing treatment is as follows: the single-stranded ultrahigh molecular weight polyethylene wrapping wire which can be developed under X-ray is spirally wound and fixed on an ultrahigh molecular weight polyethylene core wire in a medical adhesive bonding mode, and the ultrahigh molecular weight polyethylene wrapping wire consists of a wrapping wire body and a developer coated on the wrapping wire body.
Example 7
A method for preparing a developing suture capable of monitoring displacement, which is basically the same as that in embodiment 6, except that the material of the core wire, namely the ultra-high molecular weight polyethylene, is replaced by nylon, and the developer is replaced by a mixture of the developer and medical adhesive; the displacement-monitorable development stitch structure obtained by this method is the same as in example 6.
Example 8
A method for producing a displacement-monitorable development suture, substantially as in example 6, except that the ultra-high molecular weight polyethylene-covered wire is replaced with an ultra-high molecular weight polyethylene-covered wire consisting of a covered wire body and a developer dispersed in the covered wire body, the developer being coated on the covered wire body; the displacement-monitorable development stitch structure obtained by this method is the same as in example 6.
Example 9
A method for preparing a displacement-monitorable development suture, which is basically the same as that in the embodiment 6, and is characterized in that an ultrahigh molecular weight polyethylene wrapping wire is replaced by a metal nickel titanium wire with no memory characteristic, wherein the ultrahigh molecular weight polyethylene wrapping wire consists of a wrapping wire body and a developer coated on the wrapping wire body; the displacement-monitorable development stitch structure obtained by this method is the same as in example 6.
Example 10
A method for preparing a developing suture capable of monitoring displacement comprises the following steps of carrying out partial developing treatment on an ultrahigh molecular weight polyethylene core wire to obtain the developing suture capable of monitoring displacement, wherein as shown in figure 3, the partial developing treatment divides a linear region 3 on the surface of the ultrahigh molecular weight polyethylene core wire into 13 sub-regions along the length direction, one of two adjacent sub-regions is controlled to be developable under X-rays, namely a sub-region 2 which can be developed, and the other is controlled to be undevelopable under the X-rays, namely a sub-region 1 which can not be developed, and the specific process of the partial developing treatment is as follows: the developing method comprises the following steps of spirally winding double-strand ultrahigh molecular weight polyethylene wrapping wires which can be developed under X-rays and fixing the double-strand ultrahigh molecular weight polyethylene wrapping wires on ultrahigh molecular weight polyethylene core wires in a medical adhesive bonding mode, wherein the winding starting points of the double-strand ultrahigh molecular weight polyethylene wrapping wires are the same, the winding directions are clockwise and anticlockwise respectively, the winding screw pitches are the same, and the ultrahigh molecular weight polyethylene wrapping wires consist of wrapping wire bodies and developers coated on the wrapping wire bodies.
Example 11
A method for preparing a displacement-monitorable development suture, which is substantially the same as that in example 10, except that the material of the core wire, namely the ultra-high molecular weight polyethylene, is replaced by nylon, and the developer is replaced by a mixture of the developer and medical adhesive; the displacement-monitorable development stitch structure obtained by this method is the same as in example 10.
Example 12
A method for producing a displacement-monitorable development suture, substantially as in example 10, except that the ultra-high molecular weight polyethylene-covered wire is replaced with an ultra-high molecular weight polyethylene-covered wire consisting of a covered wire body and a developer dispersed in the covered wire body, the developer being coated on the covered wire body; the displacement-monitorable development stitch structure obtained by this method is the same as in example 10.
Example 13
A method for producing a displacement-monitorable development suture, which is substantially the same as in example 10, except that the ultra-high molecular weight polyethylene-covered wire is replaced by a metal nickel titanium wire having no memory characteristic, the ultra-high molecular weight polyethylene-covered wire being composed of a covered wire body and a developer coated on the covered wire body; the displacement-monitorable development stitch structure obtained by this method is the same as in example 10.
Example 14
A method for preparing a developing suture capable of monitoring displacement comprises the following steps of carrying out partial developing treatment on an ultrahigh molecular weight polyethylene core wire to obtain the developing suture capable of monitoring displacement, wherein as shown in figure 4, the partial developing treatment divides a linear region 3 on the surface of the ultrahigh molecular weight polyethylene core wire into 11 sub-regions along the length direction, one of two adjacent sub-regions is controlled to be developable under X-rays, namely a sub-region 2 which can be developed, and the other is controlled to be undevelopable under the X-rays, namely a sub-region 1 which can not be developed, and the specific process of the partial developing treatment is as follows: the double-strand wrapping wire which can be developed under X-ray is spirally wound and fixed on the core wire, the winding starting points of the double-strand wrapping wire are different, the winding directions are the same, the winding screw pitches are the same, and the ultrahigh molecular weight polyethylene wrapping wire consists of a wrapping wire body and a developer coated on the wrapping wire body.
Claims (10)
1. A preparation method of a developing suture capable of monitoring displacement is characterized by comprising the following steps: and carrying out partial development treatment on the core wire to obtain a development suture line capable of monitoring displacement, wherein the partial development treatment divides a linear region on the surface of the core wire into a plurality of sub-regions along the length direction, and one of every two adjacent sub-regions is controlled to be developable under X-rays, and the other is controlled to be undevelopable under the X-rays.
2. The method of claim 1, wherein after the partial development process, a sleeve is further woven on the surface of the core wire, the sleeve being made of the same material as the core wire.
3. The method of claim 1, wherein the core is made of ultra-high molecular weight polyethylene, nylon, polyester, or polypropylene.
4. The method for preparing a displacement-monitorable development suture according to claim 1 and wherein the specific process of the partial development treatment is as follows: and spraying a mixture of a developer and medical glue on the surface of the core wire at a certain interval, and drying and hardening.
5. The method for preparing a displacement-monitorable development suture according to claim 1 and wherein the specific process of the partial development treatment is as follows: a single strand of a wrap wire developable under X-rays is spirally wound and fixed on a core wire.
6. The method for preparing a displacement-monitorable development suture according to claim 1 and wherein the specific process of the partial development treatment is as follows: the double-strand wrapping wire which can be developed under X-ray is spirally wound and fixed on the core wire, the winding starting points of the double-strand wrapping wire are the same, the winding directions are clockwise and anticlockwise respectively, the winding screw pitches are the same, or the winding starting points of the double-strand wrapping wire are different, the winding directions are the same, and the winding screw pitches are the same.
7. The method for preparing a displacement-monitorable developing suture according to claim 5 or 6 and wherein the fixing is by means of medical adhesive.
8. The method for preparing a displacement-monitorable developing suture according to claim 5 or 6 and wherein the covered wire is composed of a covered wire body and a developer or a mixture of the developer and a medical glue coated on the covered wire body; alternatively, the first and second electrodes may be,
the wrapping wire consists of a wrapping wire body and a developer dispersed in the wrapping wire body; or the wrapping wire is a metal nickel titanium wire without memory characteristics.
9. A method of producing a displacement monitorable development suture according to claim 5 or claim 6 and wherein the material of the wrapping thread is the same as that of the core thread.
10. The displacement-monitorable development suture produced by the displacement-monitorable development suture producing method according to any one of claims 1 to 9, characterized in that: the linear region of the surface of the core wire is divided into a plurality of sub-regions along the length direction, one of every two adjacent sub-regions can be developed under X-rays, and the other one can not be developed under the X-rays.
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