CN109481727A - A kind of photocatalysis antibacterial aerogel dressing and preparation method thereof - Google Patents
A kind of photocatalysis antibacterial aerogel dressing and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/008—Hydrogels or hydrocolloids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0004—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing inorganic materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0014—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2/00—Processes of polymerisation
- C08F2/44—Polymerisation in the presence of compounding ingredients, e.g. plasticisers, dyestuffs, fillers
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- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F251/00—Macromolecular compounds obtained by polymerising monomers on to polysaccharides or derivatives thereof
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- C—CHEMISTRY; METALLURGY
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- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
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- C08J3/075—Macromolecular gels
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- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2351/00—Characterised by the use of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives of such polymers
- C08J2351/02—Characterised by the use of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives of such polymers grafted on to polysaccharides
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Abstract
The invention belongs to the technical field of medical material, a kind of photocatalysis antibacterial aerogel dressing and preparation method thereof is disclosed.Method: (1) by bismuth oxychloride ultrasonic disperse in sodium alginate soln in, mixed solution is obtained；(2) mixed solution is mixed with acrylamide, crosslinking agent, initiator, obtains pre-polymerization liquid；(3) pre-polymerization liquid is subjected to plastic, obtains photocatalysis antibacterial aerogel dressing.Present invention ultrasound removing bismuth oxychloride, effect for removing dispersion in sodium alginate soln is good；By being used in combination bismuth oxychloride and sodium alginate and acrylamide, obtained aerogel dressing not only has excellent mechanical property, while having excellent photocatalysis antibacterial effect.Method of the invention is simple, and aerogel dressing yield is big and stablizes.
Description
Technical field
The invention belongs to the technical fields of biomaterial for medical purpose, and in particular to a kind of photocatalysis antibacterial dressing and its preparation side
Method.
Background technique
Skin is to protect internal organ from external environmental interference and the important natural barrier organ for preventing from being dehydrated in vivo, after damage
Its protection mechanism can be lost.The wound infection as caused by bacterium is one of postoperative most common complication.In case of this feelings
Condition, microorganism are easy to invade and initially form bacterium colony, so as to cause serious wound infection, hinder agglutination, or even cause
The complication of threat to life.In addition, serious wounds dehydration can interfere preferably wet healing environment and delay wound healing.Cause
This, is making great efforts to develop for protecting damaged skin from the new material that infects and be dehydrated.Traditional dry dressing such as cotton, day
So or bandage and gauze are synthesized for being initially important wound healing phase, but they are dry and cannot provide tide
Wet environment, and they are also often susceptible to adhere to dry wound surface and finally cause wound after its removal.In order to gram
These disadvantages are taken, have been grown up various wet dressings by the researcher that wet wound healing concept inspires.Wherein, it especially closes
Gel is filled the water, because they can keep moist environment in wound interface, allows gas exchanges, plays the barrier to microorganism
Effect, removes excessive exudate, has excellent biocompatibility, promotes the quick healing of wound, easily remove hurtless measure.
Conventional hydrogel is made of natural or synthetic polymer, usual not anti-microbial property and bad mechanical property,
Not the problem of not can solve bacterium infection during wound healing.And current some hydrogels with anti-microbial property
Dressing usually introduces antibacterial agent or antibacterial ion, such as antibiotic, silver ion etc., and inappropriate introducing can generate toxicity to human body,
It may cause the negative effects such as drug resistance using overlong time.
Aerogel dressing of the invention has photocatalytic effect, and good anti-bacterial effect is thin by generating a large amount of ROS destruction bacteriums
After birth quickly kills bacterium, prevents the bacterium infection of wound.In addition, aerogel dressing of the invention have well elasticity and
Tensile property can be bonded wound well.Method of the invention is simple, easy to operate, and hydrogel yield is big and stablizes, mechanical property
Can be excellent, photocatalysis antibacterial effect is obvious, solves defect and deficiency of the existing technology.
Summary of the invention
In order to overcome the shortcomings and deficiencies of the prior art, the purpose of the present invention is to provide a kind of water-settings of photocatalysis antibacterial
Glue dressing and preparation method thereof.It is equal to obtain two-dimensional material dispersion by the thinned bismuth oxychloride of ultrasound in sodium alginate by the present invention
Even sodium alginate soln, then caused by heat, sodium alginate-acrylamide water-setting of preparation doping bismuth oxychloride two-dimensional material
Glue dressing.Prepared aerogel dressing has good mechanical property and good photocatalysis antibacterial performance, can effectively prevent
The only infection of wound.
The purpose of the present invention is achieved through the following technical solutions:
A kind of preparation method of photocatalysis antibacterial aerogel dressing, includes the following steps:
(1) by bismuth oxychloride ultrasonic disperse in sodium alginate soln, mixed solution is obtained；
(2) mixed solution is mixed with acrylamide, crosslinking agent, initiator, obtains pre-polymerization liquid；
(3) pre-polymerization liquid is subjected to plastic, obtains photocatalysis antibacterial aerogel dressing.
Ultrasonic condition described in step (1) is 80~300W, and 20~100Hz, ultrasonic time is 1~48h.
The dosage of bismuth oxychloride described in step (1) meets the following conditions: bismuth oxychloride accounts for sodium alginate soln and chlorine oxygen
Change the 0.075%~1.5% of bismuth gross mass.
The concentration of sodium alginate is 0.02wt%~0.2wt% in sodium alginate soln described in step (1).
Mixed solution described in step (1) specifically refers to remove bismuth oxychloride ultrasound in sodium alginate soln (A), goes
Except unstripped material, disperses supernatant in sodium alginate soln (B), obtain mixed solution；Sea is dispersed by supernatant
The concentration of sodium alginate soln (B) in solution of sodium alginate is 1.5wt%~4.8wt%.
The mass ratio of the supernatant and sodium alginate soln (B) are 1:1.The concentration of sodium alginate soln (A) is
0.02wt%~0.2wt%.
The dosage of acrylamide described in step (2) is the 6%~18.7% of mixed solution and acrylamide gross mass.
Crosslinking agent described in step (2) is N, N- methylene-bisacrylamide, N hydroxymethyl acrylamide, the initiator
For ammonium persulfate or potassium peroxydisulfate.
The dosage of crosslinking agent described in step (2) is the 0.04%~1.2% of acrylamide quality；The dosage of initiator is
The 0.05%~0.2% of acrylamide quality.
The temperature of plastic described in step (3) is 40~70 DEG C, and gelation time is 1~5h.
Hydrogel after plastic described in step (3) with a thickness of 1~3 millimeter.
The photocatalysis antibacterial aerogel dressing is prepared by above-mentioned method.
Photocatalysis antibacterial effect may be implemented in the photocatalysis antibacterial aerogel dressing under visible light conditions, is used for wound
Dressing.
Present invention ultrasound removing bismuth oxychloride, effect for removing dispersion in sodium alginate soln is good；By by oxychloride
Bismuth and sodium alginate and acrylamide are used in combination, and obtained aerogel dressing not only has excellent mechanical property, simultaneously
With excellent photocatalysis antibacterial effect.Hydrogel of the invention has elasticity and tensile property well, can be bonded well
Wound, and synchronous body movement, under the irradiation of visible light (xenon lamp 80W), by generate a large amount of ROS destroy bacterial cell membranes come
Bacterium is quickly killed, the bacterium infection of wound is prevented.Method of the invention is simple, and aerogel dressing yield is big and stablizes, mechanics
It has excellent performance, photocatalysis antibacterial effect is obvious.
The invention has the following advantages that
(1) aerogel dressing of the invention has excellent photocatalysis antibacterial effect, realizes the quick antibacterial of wound surface；
(2) method of the invention is simple, and cost is relatively low, can be with large scale preparation and production；
(3) aerogel dressing stable components prepared by, sterilization is quick, method safety, durable antibacterial effect.
Detailed description of the invention
Fig. 1 is the low power scanning electron microscope (SEM) photograph of photocatalysis antibacterial aerogel dressing in embodiment 1；
Fig. 2 is the circulation compression figure of photocatalysis antibacterial aerogel dressing in embodiment 1；
Fig. 3 is that sodium alginate-acrylamide gel (left side) is added and urges with light in embodiment 1 under illumination condition
Change the optical photograph of the plate coating of the bacterium solution after anti-bacterial hydrogel dressing (right side) is co-cultured with bacterium afterwards；
Fig. 4 is that sodium alginate-acrylamide gel (left side) is added and urges with light in embodiment 2 under illumination condition
Change the optical photograph of the plate coating of the bacterium solution after anti-bacterial hydrogel dressing (right side) is co-cultured with bacterium afterwards；
Fig. 5 is that sodium alginate-acrylamide gel (left side) is added and urges with light in embodiment 3 under illumination condition
Change the optical photograph of the plate coating of the bacterium solution after anti-bacterial hydrogel dressing (right side) is co-cultured with bacterium afterwards；
Fig. 6 is that sodium alginate-acrylamide gel (left side) is added and urges with light in embodiment 4 under illumination condition
Change the optical photograph of the plate coating of the bacterium solution after anti-bacterial hydrogel dressing (right side) is co-cultured with bacterium afterwards.
Specific embodiment
Below with reference to embodiment and attached drawing, the present invention is described in further detail, but embodiments of the present invention are unlimited
In this.
Embodiment 1
(1) bismuth oxychloride be thinned: by bismuth oxychloride (bismuth oxychloride account for (concentration be 0.025wt% sodium alginate soln+chlorine
Bismuth oxide) total dosage 0.075wt%), be added in the sodium alginate soln that concentration is 0.025wt% and mixed, will be mixed
Solution ultrasound (power 80W, the frequency 45Hz) 12h got togather, takes supernatant liquor stand-by；
It (2) with supernatant liquor is that 1:1 is mixed according to mass ratio by the sodium alginate soln that concentration is 1.5wt%, stirring is equal
After even, addition acrylamide (dosage of acrylamide is mixed liquor and the 12.5% of acrylamide gross mass) is uniformly mixed, adds
Enter the thermal initiator over cure of 0.06% crosslinking agent N,N methylene bis acrylamide relative to acrylamide quality and 0.09%
Sour ammonium is uniformly mixed, obtains pre-polymerization liquid；
(3) pre-polymerization liquid is poured into 5 centimetres of length, it is 5 centimetres wide, with a thickness of in 2 millimeters of molds, the mold of pre-polymerization liquid will be poured into
It is put into baking oven, at 50 DEG C, reacts 2.5 hours plastics, what demoulding obtained good mechanical properties has photocatalysis antibacterial performance
Aerogel dressing.
Fig. 1 is the low power scanning electron microscope (SEM) photograph in embodiment 1 with photocatalysis antibacterial aerogel dressing；Fig. 2 is in embodiment 1
The mechanical property of photocatalysis antibacterial aerogel dressing is assessed, and the circulation of aerogel dressing compresses figure.Fig. 3 is in embodiment 1 in light
According under the conditions of, be added sodium alginate-acrylamide gel (left side) and with photocatalysis antibacterial aerogel dressing (right side) afterwards and carefully
The optical photograph of the plate coating of bacterium solution after bacterium co-cultivation.
Photocatalysis antibacterial aerogel dressing manufactured in the present embodiment is under conditions of illumination, antibiotic rate 92.7%；And it is extra large
Antibiotic rate is 0% to mosanom-acrylamide gel (no bismuth oxychloride) under light illumination.Aerogel dressing manufactured in the present embodiment
Middle bismuth oxychloride extent of exfoliation is high, evenly dispersed in aerogel dressing matrix, and performance, which is stablized, has long acting antibiotic effect.
The mechanical experimental results of aerogel dressing manufactured in the present embodiment are as shown in table 1.
The mechanical property parameters of the aerogel dressing of 1 embodiment 1 of table preparation
Embodiment 2
(1) bismuth oxychloride is thinned: by bismuth oxychloride (bismuth oxychloride account for (concentration be 0.05wt% sodium alginate soln+chlorine
Bismuth oxide) total dosage 0.1wt%), be added in the sodium alginate soln that concentration is 0.05wt% and mixed, will be mixed
Solution ultrasound (power 100W, frequency 45Hz) 10h, take supernatant liquor stand-by；
It (2) with supernatant liquor is that 1:1 is mixed according to mass ratio by the sodium alginate soln that concentration is 1.75wt%, stirring is equal
After even, addition acrylamide (dosage of acrylamide is mixed liquor and the 15% of acrylamide gross mass) is uniformly mixed, is added
Relative to acrylamide quality 0.06% crosslinking agent N,N methylene bis acrylamide and 0.09% thermal initiator persulfuric acid
Ammonium is uniformly mixed, obtains pre-polymerization liquid；
(3) pre-polymerization liquid is poured into 5 centimetres of length, it is 5 centimetres wide, with a thickness of in 2 millimeters of molds, the mold of pre-polymerization liquid will be poured into
It is put into baking oven, at 50 DEG C, reacts 2.5 hours plastics, what demoulding obtained good mechanical properties has photocatalysis antibacterial performance
Aerogel dressing.Photocatalysis antibacterial aerogel dressing manufactured in the present embodiment is under conditions of illumination, antibiotic rate 100%.
Fig. 4 is that sodium alginate-acrylamide gel (left side) is added and has photocatalysis antibacterial water in embodiment 2 under illumination condition
The optical photograph that gel dressing (right side) is coated with the plate of the bacterium solution after bacterium (Escherichia coli) co-cultivation afterwards.
Bismuth oxychloride extent of exfoliation is high in aerogel dressing manufactured in the present embodiment, uniformly divides in aerogel dressing matrix
It dissipates, performance, which is stablized, has long acting antibiotic effect.
The mechanical experimental results of aerogel dressing manufactured in the present embodiment are as shown in table 2.
The mechanical property parameters of the aerogel dressing of 2 embodiment 2 of table preparation
Embodiment 3
(1) bismuth oxychloride is thinned: by bismuth oxychloride (bismuth oxychloride account for (concentration be 0.1wt% sodium alginate soln+chlorine
Bismuth oxide) total dosage 0.125wt%), be added in the sodium alginate soln that concentration is 0.1wt% and mixed, will be mixed
Good solution ultrasound (power 150W, frequency 45Hz) 8h, takes supernatant stand-by；
(2) with supernatant liquor it is that 1:1 is mixed according to mass ratio by the sodium alginate soln that concentration is 2wt%, stirs evenly
Afterwards, addition acrylamide (dosage of acrylamide is mixed liquor and the 16% of acrylamide gross mass), is uniformly mixed, phase is added
0.08% crosslinking agent N, N- methylene-bisacrylamide for acrylamide quality and 0.1% thermal initiator ammonium persulfate,
It is uniformly mixed, obtains pre-polymerization liquid；
(3) pre-polymerization liquid is poured into 5 centimetres of length, it is 5 centimetres wide, with a thickness of in 2 millimeters of molds, the mold of pre-polymerization liquid will be poured into
It is put into baking oven, at 50 DEG C, reacts 2.5 hours plastics, what demoulding obtained good mechanical properties has photocatalysis antibacterial performance
Aerogel dressing.Photocatalysis antibacterial aerogel dressing manufactured in the present embodiment is under conditions of illumination, antibiotic rate 100%.
Fig. 5 is that sodium alginate-acrylamide gel (left side) is added and has photocatalysis antibacterial water in embodiment 3 under illumination condition
The optical photograph that gel dressing (right side) is coated with the plate of the bacterium solution after bacterium co-cultivation afterwards.Hydrogel manufactured in the present embodiment applies
Bismuth oxychloride extent of exfoliation is high in material, evenly dispersed in aerogel dressing matrix, and performance, which is stablized, has long acting antibiotic effect.
The mechanical experimental results of aerogel dressing manufactured in the present embodiment are as shown in table 3.
The mechanical property parameters of the aerogel dressing of 3 embodiment 3 of table preparation
Embodiment 4
(1) bismuth oxychloride is thinned: by bismuth oxychloride (bismuth oxychloride account for (concentration be 0.15wt% sodium alginate soln+chlorine
Bismuth oxide) total dosage 0.15wt%), be added in the sodium alginate soln that concentration is 0.15wt% and mixed, will be mixed
Good solution ultrasound (power 200W, frequency 45Hz) 5h, takes supernatant liquor；
It (2) with supernatant liquor is that 1:1 is mixed according to mass ratio by the sodium alginate soln that concentration is 2.25wt%, stirring is equal
After even, addition acrylamide (dosage of acrylamide is mixed liquor and the 18% of acrylamide gross mass) is uniformly mixed, is added
Relative to acrylamide quality 0.08% crosslinking agent N,N methylene bis acrylamide and 0.1% thermal initiator persulfuric acid
Ammonium is uniformly mixed, obtains pre-polymerization liquid；
(3) pre-polymerization liquid is poured into 5 centimetres of length, it is 5 centimetres wide, with a thickness of in 2 millimeters of molds, the mold of pre-polymerization liquid will be poured into
It is put into baking oven, at 50 DEG C, reacts 2.5 hours plastics, what demoulding obtained good mechanical properties has photocatalysis antibacterial performance
Aerogel dressing.Photocatalysis antibacterial aerogel dressing manufactured in the present embodiment is under conditions of illumination, antibiotic rate 100%.
Fig. 6 is that sodium alginate-acrylamide gel (left side) is added and has photocatalysis antibacterial water in embodiment 4 under illumination condition
The optical photograph that gel dressing (right side) is coated with the plate of the bacterium solution after bacterium (Escherichia coli) co-cultivation afterwards.
Bismuth oxychloride extent of exfoliation is high in aerogel dressing manufactured in the present embodiment, uniformly divides in aerogel dressing matrix
It dissipates, performance, which is stablized, has long acting antibiotic effect.
The mechanical experimental results of aerogel dressing manufactured in the present embodiment are as shown in table 4.
The mechanical property parameters of the aerogel dressing of 4 embodiment 4 of table preparation
The mechanical property provided from Examples 1 to 4 is it is found that bismuth oxychloride extent of exfoliation is high, in aerogel dressing matrix
It is evenly dispersed, and there is no the mechanical properties for reducing hydrogel.
Claims (9)
1. a kind of preparation method of photocatalysis antibacterial aerogel dressing, characterized by the following steps:
(1) by bismuth oxychloride ultrasonic disperse in sodium alginate soln, mixed solution is obtained；
(2) mixed solution is mixed with acrylamide, crosslinking agent, initiator, obtains pre-polymerization liquid；
(3) pre-polymerization liquid is subjected to plastic, obtains photocatalysis antibacterial aerogel dressing.
2. the preparation method of photocatalysis antibacterial aerogel dressing according to claim 1, it is characterised in that: institute in step (1)
The dosage for stating bismuth oxychloride meets the following conditions: bismuth oxychloride accounts for the 0.075% of sodium alginate soln and bismuth oxychloride gross mass
~1.5%；
The concentration of sodium alginate is 0.02wt%~0.2wt% in sodium alginate soln described in step (1).
3. the preparation method of photocatalysis antibacterial aerogel dressing according to claim 1, it is characterised in that: institute in step (2)
The dosage for stating acrylamide is the 6%~18.7% of mixed solution and acrylamide gross mass.
4. the preparation method of photocatalysis antibacterial aerogel dressing according to claim 1, it is characterised in that: institute in step (2)
Stating crosslinking agent is N, N- methylene-bisacrylamide or N hydroxymethyl acrylamide, and the initiator is ammonium persulfate or persulfuric acid
Potassium.
5. the preparation method of photocatalysis antibacterial aerogel dressing according to claim 1, it is characterised in that: institute in step (2)
The dosage for stating crosslinking agent is the 0.04%~1.2% of acrylamide quality；The dosage of initiator is acrylamide quality
0.05%~0.2%.
6. the preparation method of photocatalysis antibacterial aerogel dressing according to claim 1, it is characterised in that:
Ultrasonic condition described in step (1) is 80~300W, and 20~100Hz, ultrasonic time is 1~48h；
Mixed solution described in step (1) specifically refers to remove bismuth oxychloride ultrasound in sodium alginate soln, is centrifuged, removal
Unstripped material, disperses supernatant in sodium alginate soln, obtains mixed solution.
7. the preparation method of photocatalysis antibacterial aerogel dressing according to claim 6, it is characterised in that: disperse supernatant
The concentration of sodium alginate soln in sodium alginate soln is 1.5wt%~4.8wt%；The supernatant and sodium alginate are molten
The mass ratio of liquid is 1:1.
8. the preparation method of photocatalysis antibacterial aerogel dressing according to claim 1, it is characterised in that: institute in step (3)
The temperature for stating plastic is 40~70 DEG C, and gelation time is 1~5h.
9. a kind of photocatalysis antibacterial aerogel dressing that the preparation method as described in claim 1 obtains.
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Cited By (5)
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| CN109985668A (en) * | 2019-04-29 | 2019-07-09 | 西北师范大学 | A kind of micro-nano multi-layer material of chitosan hybrid bismuth oxybromide and its preparation and application |
| CN112993448A (en) * | 2021-02-22 | 2021-06-18 | 辽宁大学 | BiOCl gel electrode and application thereof in preparation of novel solar metal-air cell |
| CN113101973A (en) * | 2021-04-12 | 2021-07-13 | 天津城建大学 | High-activity photochromic bismuth oxychloride/calcium alginate photocatalytic hydrogel microsphere and preparation method thereof |
| CN115252777A (en) * | 2022-06-09 | 2022-11-01 | 南昌大学 | In-situ whitening and anti-caries gel and preparation method thereof |
| CN115317660A (en) * | 2022-07-29 | 2022-11-11 | 沈阳药科大学 | Near-infrared response antibacterial nano composite hydrogel dressing |
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