CN106860968A - Monitor the monitoring alarm of venous transfusion - Google Patents
Monitor the monitoring alarm of venous transfusion Download PDFInfo
- Publication number
- CN106860968A CN106860968A CN201710138144.7A CN201710138144A CN106860968A CN 106860968 A CN106860968 A CN 106860968A CN 201710138144 A CN201710138144 A CN 201710138144A CN 106860968 A CN106860968 A CN 106860968A
- Authority
- CN
- China
- Prior art keywords
- monitoring
- alarm
- venous transfusion
- film layer
- pcb board
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000012544 monitoring process Methods 0.000 title claims abstract description 50
- 230000005540 biological transmission Effects 0.000 claims abstract description 19
- 238000010253 intravenous injection Methods 0.000 claims abstract description 17
- 238000001514 detection method Methods 0.000 claims description 28
- 239000004020 conductor Substances 0.000 claims description 23
- 210000000707 wrist Anatomy 0.000 claims description 16
- 230000006698 induction Effects 0.000 claims description 5
- 238000004513 sizing Methods 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 4
- 239000010408 film Substances 0.000 claims 8
- 239000002305 electric material Substances 0.000 claims 1
- 239000010409 thin film Substances 0.000 claims 1
- 238000002347 injection Methods 0.000 abstract description 3
- 239000007924 injection Substances 0.000 abstract description 3
- 230000002159 abnormal effect Effects 0.000 description 9
- 239000007788 liquid Substances 0.000 description 4
- 239000003814 drug Substances 0.000 description 3
- 230000005611 electricity Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000002390 adhesive tape Substances 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 230000006641 stabilisation Effects 0.000 description 2
- 238000011105 stabilization Methods 0.000 description 2
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 229920002799 BoPET Polymers 0.000 description 1
- 206010028851 Necrosis Diseases 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 208000010513 Stupor Diseases 0.000 description 1
- 208000003443 Unconsciousness Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 231100000429 cutaneous necrosis Toxicity 0.000 description 1
- 229940127089 cytotoxic agent Drugs 0.000 description 1
- 239000002254 cytotoxic agent Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
- A61M5/16836—Monitoring, detecting, signalling or eliminating infusion flow anomalies by sensing tissue properties at the infusion site, e.g. for detecting infiltration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/18—General characteristics of the apparatus with alarm
Abstract
The present invention relates to a kind of monitoring alarm for monitoring venous transfusion, including mechanism for monitoring and alarm mechanism, mechanism for monitoring is attached at the intravenous injection of human body, and after the surface area change overrate of the skin at the intravenous injection of human body, transmission alarm signal sends sound, light or vibrating alert medical worker to alarm mechanism by alarm mechanism.Using such scheme, the present invention provides a kind of timely monitoring alarm for finding injection leakage and the monitoring venous transfusion of alarm being sent after leakage is injected, so as to avoid because leakage by transfusion person to being damaged.
Description
Technical field
The present invention relates to a kind of medical facilities, and in particular to a kind of monitoring alarm of monitoring venous transfusion.
Background technology
Venous transfusion is by quiet using atmospheric pressure, fluid pressure or mechanical pressure principle by sterile liquid, electrolyte, medicine
Arteries and veins is input into internal method.Because its treatment layer is wide, human body stimulates small, it is widely used.
And during venous transfusion, it is possible that phenomenon of the fluid seepage to extravascular tissue gap, if leakage
Continue and if not timely discovery, some specific drugs can bring localized injury to human body, such as cytotoxic drug, blood vessel are lived
Property medicine etc., in addition, after leaking liquid amount reaches to a certain degree, the blood vessel under skin can be oppressed by leakage, causes cutaneous necrosis, more
Limb necrosis can notably be caused.
Above-mentioned situation is concentrated in the case of coming across to the observation inconvenience of transfusion situation, such as defeated after patient's anesthesia in operating room
Liquid position is covered by aseptic drape, or because patient lacks independent behaviour ability, such as unconsciousness, the patient of stupor, therefore
The device for monitoring venous transfusion situation constantly is needed to avoid above-mentioned harsh conditions from occurring.
The content of the invention
In view of the shortcomings of the prior art, it is an object of the invention to provide it is a kind of find in time injection leakage and
The monitoring alarm of the monitoring venous transfusion of alarm is sent after injection leakage, so as to avoid hindering caused by leakage is to by transfusion person
Evil.
To achieve the above object, the invention provides following technical scheme:It is described including mechanism for monitoring and alarm mechanism
Mechanism for monitoring is attached at the intravenous injection of human body, and the surface area change of the skin at the intravenous injection of human body exceedes volume
After definite value, transmission alarm signal sends sound, light or vibrating alert medical worker to alarm mechanism by alarm mechanism.
By using above-mentioned technical proposal, mechanism for monitoring is detected to the surface area of the skin at intravenous injection, from
And venous transfusion is inferred with the presence or absence of leakage and leakage degree, after leakage reaches to a certain degree, alarm mechanism and alarm are carried
Wake up medical worker, and treatment transfusion in time is abnormal, so as to avoid because leakage by transfusion person to being damaged.
The present invention is further arranged to:Described mechanism for monitoring by fexible film, can deformation conductive material and resistance detection
Module is constituted, and described fexible film includes the upper thin flexible film layer and lower thin flexible film layer that are stacked, described upper flexibility
Constituted between film layer and lower thin flexible film layer fixation can deformation conductive material lock chamber, it is described can deformation conductive material point
It is not provided with and is connected in first connection end and the second connection end of resistance detection module.
By using above-mentioned technical proposal, fexible film can deformation conductive material be fixed and be attached to skin table
Layer, the skin expansion heaved when venous transfusion leakage causes conductive material deformation, according to can deformation conductive material electricity it is special
Property, can deformation conductive material be distorted rear resistance and can produce change, learn flexibility after being changed by resistance detection module detection resistance
Film produces change.
The present invention is further arranged to:Described upper thin flexible film layer or lower thin flexible film layer is provided with and is attached to skin
Sizing portion.
By using above-mentioned technical proposal, sizing portion is set up, fexible film is attached directly to skin, nothing when in use
Need adhesive tape to coordinate to be fixed.
The present invention is further arranged to:It is described can deformation conductive material be provided with it is corresponding at the intravenous injection with human body
And spiral induction part.
By using above-mentioned technical proposal, due to heaving at the intravenous injection of human body be centered on being injected intravenously place to
Surrounding diffusion, by can deformation conductive material induction part arrangement in the shape of a spiral, and when in use by helical sun and human body
Intravenous injection at it is relative, can fast and accurately by the change of the surface area of resistance variations senses skin, so as to improve
Sensitive monitoring, finds that transfusion is abnormal in time, can deformation conductive material can also other forms arrangement, such as parallel arrangement, U-shaped
Arrangement etc..
The present invention is further arranged to:Described mechanism for monitoring also includes pcb board, and described pcb board is provided with control electricity
Road, the detection data of described resistance detection module is transmitted to control circuit and comparison with wired or wireless transmission means,
Such as exceed rating number, alarm mechanism is started with wired or wireless transmission means.
By using above-mentioned technical proposal, control circuit is contrasted the detection data that resistance detection module draws,
Alarm mechanism alarm is controlled after overrate, makes the device more intelligent, no matter detection data transmission and control circuit
The transmission of control signal, can be adjusted according to actual conditions between wired or wireless transmission means.
The present invention is further arranged to, and described mechanism for monitoring also includes the box body equipped with the first wrist strap, described pcb board
And resistance detection module is installed in the box body.
By using above-mentioned technical proposal, for the pcb board and the box body of resistance detection module installed, worn by the first wrist strap
Wear at the wrist by transfusion person, moved with by the wrist of transfusion person, it is ensured that the stabilization installation of device, it is to avoid because of the dislocation of device
Influence accurate measurements.
The present invention is further arranged to, and described alarm mechanism is the buzzer for being installed on pcb board.
By using above-mentioned technical proposal, buzzer can send sharp sound prompting medical matters people when infusing abnormal
Member, it is also possible to which other sound generators replace.
The present invention is further arranged to, and described alarm mechanism is the vibrations motor equipped with the second wrist strap.
By using above-mentioned technical proposal, the second wrist strap is wearable in the wrist of medical worker, is shaken when infusing abnormal
Dynamic motor sends vibration reminding medical worker, it is also possible to which other vibrations generators replace.
The present invention is further arranged to, and described alarm mechanism is the LED for being installed on pcb board.
The light prompting medical worker of flicker is sent when infusing abnormal, also may be used by using above-mentioned technical proposal, LED
Replaced with other light beam generators.
The invention will be further described with specific implementation transmission means below in conjunction with the accompanying drawings.
Brief description of the drawings
Fig. 1 is the principle schematic of the specific embodiment of the invention;
Fig. 2 is the structural representation of the specific embodiment of the invention;
Fig. 3 be the specific embodiment of the invention in fexible film and can deformation conductive material exploded perspective view.
Specific implementation transmission means
As shown in Fig. 1-Fig. 3, the invention discloses it is a kind of monitor venous transfusion monitoring alarm, including mechanism for monitoring and
Alarm mechanism 1, mechanism for monitoring is attached at the intravenous injection of human body, and the skin at the intravenous injection of human body surface area
After change overrate, transmission alarm signal to alarm mechanism 1 sends sound, light or vibrating alert and cures by alarm mechanism 1
Business personnel, mechanism for monitoring is detected to the surface area of the skin at intravenous injection, so as to infer that venous transfusion whether there is
Leakage and leakage degree, after leakage reaches to a certain degree, alarm mechanism 1 and alarm remind medical worker, process in time defeated
Liquid exception, so as to avoid because leakage by transfusion person to being damaged.
Mechanism for monitoring by fexible film 2, can deformation conductive material 3 and resistance detection module 4 constitute, fexible film 2 includes
The upper thin flexible film layer 21 and lower thin flexible film layer 22 being stacked, structure between upper thin flexible film layer 21 and lower thin flexible film layer 22
Into fixation can deformation conductive material 3 lock chamber, can deformation conductive material 3 be respectively arranged with and be connected in resistance detection module 4
First connection end 31 and the second connection end 32, fexible film 2 can deformation conductive material 3 be fixed and be attached to skin table
Layer, the skin expansion heaved when venous transfusion leakage causes the deformation of conductive material 3, according to can deformation conductive material 3 electricity
Characteristic, can deformation conductive material 3 be distorted rear resistance and can produce change, learnt after being changed by the detection resistance of resistance detection module 4
Fexible film 2 produces change, and fexible film 2 can be using similar materials such as plastic sheeting, mylars, can deformation conductive material 3
Can be using the similar material such as electric silica gel, resistance detection module 4 can the existing module such as model AY-RM Module.
Upper thin flexible film layer 21 or lower thin flexible film layer 22 are provided with the sizing portion 23 for being attached to skin, set up sizing portion
23, fexible film 2 is attached directly to skin when in use, coordinate without adhesive tape and be fixed.
Can deformation conductive material 3 be provided with corresponding at the intravenous injection with human body and spiral induction part 33, by
Heaving at the intravenous injection of human body is spread to surrounding centered on being injected intravenously place, by can deformation conductive material 3
Induction part 33 is arranged in the shape of a spiral, and relative at the intravenous injection by helical sun with human body when in use, can quickly and
The change of the accurate surface area by resistance variations senses skin, so as to improve sensitive monitoring, finds that transfusion is abnormal in time.
Mechanism for monitoring also includes pcb board 5, and pcb board 5 is provided with control circuit, and the detection data of resistance detection module 4 is having
Line or wireless transmission means are transmitted to control circuit and comparison, such as exceed rating number, with wired or wireless transmission side
Formula starts alarm mechanism 1, and control circuit is contrasted the detection data that resistance detection module 4 draws, after overrate
Control alarm mechanism 1 alarm, make device more intelligent, no matter detection data transmission and control circuit control signal biography
It is defeated, can be adjusted between wired or wireless transmission means according to actual conditions, wired transmission means is by leading
Line is connected, and wireless transmission means can be wifi module, bluetooth module, infrared module etc., and the comparison process of control circuit can
Completed by existing microprocessor, model such as 14305R-2000 etc..
Mechanism for monitoring also includes the box body 6 equipped with the first wrist strap 61, and pcb board 5 and resistance detection module 4 are installed on the box body
In 6, for the pcb board 5 and the box body 6 of resistance detection module 4 installed, it is worn on by the wrist of transfusion person by the first wrist strap 61
Place, moves with by the wrist of transfusion person, it is ensured that the stabilization installation of device, it is to avoid because the dislocation of device influences accurate measurements.
Alarm mechanism 1 is the buzzer for being installed on pcb board 5, and buzzer can send sharp sound when infusing abnormal
Remind medical worker, it is also possible to which other sound generators replace.
Alarm mechanism 1 is the vibrations motor equipped with the second wrist strap, and the second wrist strap is wearable in the wrist of medical worker,
Vibrations motor sends vibration reminding medical worker when transfusion is abnormal, it is also possible to which other vibrations generators replace.
Alarm mechanism 1 is the LED for being installed on pcb board 5, and LED sends the light prompting doctor of flicker when infusing abnormal
Business personnel, it is also possible to which other light beam generators replace.
Power supply is additionally provided with pcb board 5 for each component is powered.
Claims (9)
1. it is a kind of monitor venous transfusion monitoring alarm, it is characterised in that:It is described including mechanism for monitoring and alarm mechanism
Mechanism for monitoring is attached at the intravenous injection of human body, and the surface area change of the skin at the intravenous injection of human body exceedes volume
After definite value, transmission alarm signal sends sound, light or vibrating alert medical worker to alarm mechanism by alarm mechanism.
2. it is according to claim 1 monitoring venous transfusion monitoring alarm, it is characterised in that:Described mechanism for monitoring
Including fexible film, can deformation conductive material and resistance detection module, described fexible film includes the upper flexibility being stacked
Film layer and lower thin flexible film layer, constituting fixation between described upper thin flexible film layer and lower thin flexible film layer can deformation conduction material
The lock chamber of material, it is described can deformation conductive material be respectively arranged with and be connected in resistance detection module and extend to outside fexible film
The first connection end and the second connection end.
3. it is according to claim 2 monitoring venous transfusion monitoring alarm, it is characterised in that:Described upper flexible thin
Film layer or lower thin flexible film layer are provided with the sizing portion for being attached to skin.
4. it is according to claim 2 monitoring venous transfusion monitoring alarm, it is characterised in that:It is described can deformation lead
Electric material is provided with corresponding at the intravenous injection with human body and spiral induction part.
5. it is according to claim 2 monitoring venous transfusion monitoring alarm, it is characterised in that:Described mechanism for monitoring
Also include pcb board, described pcb board is provided with control circuit, the detection data of described resistance detection module is with wired or nothing
The transmission means of line is transmitted to control circuit and comparison, such as exceedes rating number, is started with wired or wireless transmission means
Alarm mechanism.
6. it is according to claim 3 monitoring venous transfusion monitoring alarm, it is characterised in that:Described mechanism for monitoring
Also include the box body equipped with the first wrist strap, described pcb board and resistance detection module is installed in the box body.
7. according to claim 5 or 6 monitoring venous transfusion monitoring alarm, it is characterised in that:Described alarm
Mechanism is the buzzer for being installed on pcb board.
8. according to claim 5 or 6 monitoring venous transfusion monitoring alarm, it is characterised in that:Described alarm
Mechanism is the vibrations motor equipped with the second wrist strap.
9. according to claim 5 or 6 monitoring venous transfusion monitoring alarm, it is characterised in that:Described alarm
Mechanism is the LED for being installed on pcb board.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710138144.7A CN106860968A (en) | 2017-03-09 | 2017-03-09 | Monitor the monitoring alarm of venous transfusion |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710138144.7A CN106860968A (en) | 2017-03-09 | 2017-03-09 | Monitor the monitoring alarm of venous transfusion |
Publications (1)
Publication Number | Publication Date |
---|---|
CN106860968A true CN106860968A (en) | 2017-06-20 |
Family
ID=59170361
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710138144.7A Pending CN106860968A (en) | 2017-03-09 | 2017-03-09 | Monitor the monitoring alarm of venous transfusion |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106860968A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111329451A (en) * | 2020-03-19 | 2020-06-26 | 杭州市余杭区中医院 | Intravenous injection edema detection device |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN201058150Y (en) * | 2007-07-27 | 2008-05-14 | 天津医科大学总医院 | Alarm apparatus for venous transfusion |
WO2016041876A1 (en) * | 2014-09-15 | 2016-03-24 | Sanofi | Injection devices with tissue sewelling detection |
WO2016089307A1 (en) * | 2014-12-02 | 2016-06-09 | Agency for Science,Technology and Research | Sensor patch and sensing device having the same |
CN207640745U (en) * | 2017-03-09 | 2018-07-24 | 杨良慧 | Monitor the monitoring alarm of venous transfusion |
-
2017
- 2017-03-09 CN CN201710138144.7A patent/CN106860968A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN201058150Y (en) * | 2007-07-27 | 2008-05-14 | 天津医科大学总医院 | Alarm apparatus for venous transfusion |
WO2016041876A1 (en) * | 2014-09-15 | 2016-03-24 | Sanofi | Injection devices with tissue sewelling detection |
WO2016089307A1 (en) * | 2014-12-02 | 2016-06-09 | Agency for Science,Technology and Research | Sensor patch and sensing device having the same |
CN207640745U (en) * | 2017-03-09 | 2018-07-24 | 杨良慧 | Monitor the monitoring alarm of venous transfusion |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111329451A (en) * | 2020-03-19 | 2020-06-26 | 杭州市余杭区中医院 | Intravenous injection edema detection device |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US4711248A (en) | Physiological pressure monitor | |
WO2017088153A1 (en) | Leakage detection device for medical devices | |
AU2014317795B2 (en) | Wearable intravenous fluid delivery system | |
WO2016183981A1 (en) | Infusion system and method of controlling flow rate of liquid medicine of infusion system | |
KR20060058695A (en) | Device for monitoring the condition of a human being | |
DE60239104D1 (en) | DEVICE FOR PAIN RELIEF AND ANALYSIS IN CONNECTION WITH MEDICAL OR SURGICAL PROCEDURE | |
US10159779B2 (en) | Vital sleeve | |
CN107617135B (en) | A kind of safe infusion device | |
US20230033130A1 (en) | Closed-loop artificial pancreas controlled by body movements | |
CN207640745U (en) | Monitor the monitoring alarm of venous transfusion | |
CN111249572A (en) | Vital sign monitoring system | |
CN108937947A (en) | A kind of early warning type body posture apparatus for correcting and system | |
CN106860968A (en) | Monitor the monitoring alarm of venous transfusion | |
AU2018247480A1 (en) | Bandage for monitoring swelling at a selected site on the body of a patient and method of monitoring swelling at a selected site on the body of a patient | |
US20200054279A1 (en) | Bandage for monitoring swelling at a selected site on the body of a patient and method of monitoring swelling at a selected site on the body of a patient | |
CN209033376U (en) | A kind of transfusion nursing equipment | |
CN209153718U (en) | Limb muscle soft tissue pressure non-invasive monitoring device | |
CN209611894U (en) | A kind of device for Transfusion infiltration processing | |
CN203709997U (en) | Temperature stimulation based human body feeling detection device | |
CN208339927U (en) | A kind of anti-scald protection circuit of probe applied to ultrasonic conductivity gauge | |
KR20170013314A (en) | Device for the non-invasive measurement of blood flow | |
CN207168829U (en) | A kind of disposable physiotherapy electrode plate | |
CN108325022A (en) | A kind of monitoring infusion warning device | |
CN212575413U (en) | Infusion monitoring fixing device | |
CN215961556U (en) | Reminding device for medicine exudation in venous transfusion |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170620 |
|
RJ01 | Rejection of invention patent application after publication |